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The map label for this gene is lpxK

Identifier: 71892156

GI number: 71892156

Start: 456296

End: 457309

Strand: Reverse

Name: lpxK

Synonym: BPEN_389

Alternate gene names: 71892156

Gene position: 457309-456296 (Counterclockwise)

Preceding gene: 71892157

Following gene: 71892155

Centisome position: 57.77

GC content: 33.83

Gene sequence:

>1014_bases
ATGTTTGATCGTATTTGGTTTAAATCATCGTTTTTTTATTTATTTTTATTGCCATTTTCTTGGTTATACGGTGTAATCAG
TACACTGAATCGTATTAGTTATCAGTATGGATGGCGAAAAGTATATCGATTTTCGGTACCAATAATAATTATTGGTAATT
TAACAATTGGAGGCAACGGGAAAACTCCGATGGTATTATGGTTAGTAGAGCACTTGAAACGTCGTGGTTGGAAGGTTGGG
GTAATTTCAAGAGGATATAAAGGTAAATCGAATAATTATCCAATAATTATTAATATGAATAGCCATAGTGAGGAATGTGG
TGATGAGCCTATGTTAATTTGGAAACGAACTGGAGTATCGGTCGCTGTTTCTCCAAAACGTGCTGATGCAGTTGCTGCAT
TATTGAGAAAACAAGAATTGGACATCATAATAAGTGATGATGGATTACAACATTATGCACTTTTTAGGGATATAGAATGG
GTAATAGTTAATAGTGTGCTTCGATTTGGAAATGGTTGTTGGTTACCAGCAGGTCCCATGCGCGAACGCATTAATAGACT
TCATACAGTACAAGCGATTATTGCAAATGGATCAGAAGTAGGAATACAATCTGGAGAAGTATTAATGCAGTTATTTCCTA
TCGCTGTAGTCAATATATTGACGGGAGAGCGTAAACCTCTTTATTTTTTAAATAATGTTGTAGCTATAGCAGGGATTGGG
TATCCTACACAATTTTTTGATACTTTACGAAGTTATGGGATCATTCCGATCAGATCAATTTCATTTTCTGATCATCACGT
GTATTCTGAAAAAATGTTAACATCTCTTACTAAAAAAGATGAGATATTACTAATGACCGAAAAAGATGCAGTTAAATGTA
TAGATTTTGCTCACGATAATTGGTGGTACGTGCATACAGAAGTAAAAATCAATAAGATAGATACGCATAATTTATTGAGC
ATGGTAGAAAATAAGATCAGATATTATAAGGGTTCAAGATACAATGTACAGTAA

Upstream 100 bases:

>100_bases
TAATTGAAAATGGTTATATTATGGAACGTGGTGTGCATAAGGTTTTGATACGTCGCCAAGGGATTTATGCTCAATTATAT
AAATTGCAATTTTCTTCTTA

Downstream 100 bases:

>100_bases
TTATATTTTCACAACAATATGATAACCATTTAGGAGAAAGATTAGAAAATAATATTTTAAGTGTGGTTTTTATATATGAC
ATTGTCATATATAAAAAAAA

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MFDRIWFKSSFFYLFLLPFSWLYGVISTLNRISYQYGWRKVYRFSVPIIIIGNLTIGGNGKTPMVLWLVEHLKRRGWKVG
VISRGYKGKSNNYPIIINMNSHSEECGDEPMLIWKRTGVSVAVSPKRADAVAALLRKQELDIIISDDGLQHYALFRDIEW
VIVNSVLRFGNGCWLPAGPMRERINRLHTVQAIIANGSEVGIQSGEVLMQLFPIAVVNILTGERKPLYFLNNVVAIAGIG
YPTQFFDTLRSYGIIPIRSISFSDHHVYSEKMLTSLTKKDEILLMTEKDAVKCIDFAHDNWWYVHTEVKINKIDTHNLLS
MVENKIRYYKGSRYNVQ

Sequences:

>Translated_337_residues
MFDRIWFKSSFFYLFLLPFSWLYGVISTLNRISYQYGWRKVYRFSVPIIIIGNLTIGGNGKTPMVLWLVEHLKRRGWKVG
VISRGYKGKSNNYPIIINMNSHSEECGDEPMLIWKRTGVSVAVSPKRADAVAALLRKQELDIIISDDGLQHYALFRDIEW
VIVNSVLRFGNGCWLPAGPMRERINRLHTVQAIIANGSEVGIQSGEVLMQLFPIAVVNILTGERKPLYFLNNVVAIAGIG
YPTQFFDTLRSYGIIPIRSISFSDHHVYSEKMLTSLTKKDEILLMTEKDAVKCIDFAHDNWWYVHTEVKINKIDTHNLLS
MVENKIRYYKGSRYNVQ
>Mature_337_residues
MFDRIWFKSSFFYLFLLPFSWLYGVISTLNRISYQYGWRKVYRFSVPIIIIGNLTIGGNGKTPMVLWLVEHLKRRGWKVG
VISRGYKGKSNNYPIIINMNSHSEECGDEPMLIWKRTGVSVAVSPKRADAVAALLRKQELDIIISDDGLQHYALFRDIEW
VIVNSVLRFGNGCWLPAGPMRERINRLHTVQAIIANGSEVGIQSGEVLMQLFPIAVVNILTGERKPLYFLNNVVAIAGIG
YPTQFFDTLRSYGIIPIRSISFSDHHVYSEKMLTSLTKKDEILLMTEKDAVKCIDFAHDNWWYVHTEVKINKIDTHNLLS
MVENKIRYYKGSRYNVQ

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family

Homologues:

Organism=Escherichia coli, GI1787144, Length=324, Percent_Identity=46.9135802469136, Blast_Score=328, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXK_BLOPB (Q492T0)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277888.1
- ProteinModelPortal:   Q492T0
- STRING:   Q492T0
- GeneID:   3562654
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_389
- eggNOG:   COG1663
- HOGENOM:   HBG663914
- OMA:   VILMDDG
- ProtClustDB:   PRK00652
- BioCyc:   CBLO291272:BPEN_389-MONOMER
- HAMAP:   MF_00409
- InterPro:   IPR003758
- TIGRFAMs:   TIGR00682

Pfam domain/function: PF02606 LpxK

EC number: =2.7.1.130

Molecular weight: Translated: 38818; Mature: 38818

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRIWFKSSFFYLFLLPFSWLYGVISTLNRISYQYGWRKVYRFSVPIIIIGNLTIGGNG
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEECCEEEEEEEEECCCC
KTPMVLWLVEHLKRRGWKVGVISRGYKGKSNNYPIIINMNSHSEECGDEPMLIWKRTGVS
CCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCCCHHHCCCCEEEEEECCCE
VAVSPKRADAVAALLRKQELDIIISDDGLQHYALFRDIEWVIVNSVLRFGNGCWLPAGPM
EEECCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RERINRLHTVQAIIANGSEVGIQSGEVLMQLFPIAVVNILTGERKPLYFLNNVVAIAGIG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHCCEEEEEECC
YPTQFFDTLRSYGIIPIRSISFSDHHVYSEKMLTSLTKKDEILLMTEKDAVKCIDFAHDN
CCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCC
WWYVHTEVKINKIDTHNLLSMVENKIRYYKGSRYNVQ
EEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFDRIWFKSSFFYLFLLPFSWLYGVISTLNRISYQYGWRKVYRFSVPIIIIGNLTIGGNG
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEECCEEEEEEEEECCCC
KTPMVLWLVEHLKRRGWKVGVISRGYKGKSNNYPIIINMNSHSEECGDEPMLIWKRTGVS
CCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCCCHHHCCCCEEEEEECCCE
VAVSPKRADAVAALLRKQELDIIISDDGLQHYALFRDIEWVIVNSVLRFGNGCWLPAGPM
EEECCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RERINRLHTVQAIIANGSEVGIQSGEVLMQLFPIAVVNILTGERKPLYFLNNVVAIAGIG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHCCEEEEEECC
YPTQFFDTLRSYGIIPIRSISFSDHHVYSEKMLTSLTKKDEILLMTEKDAVKCIDFAHDN
CCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCC
WWYVHTEVKINKIDTHNLLSMVENKIRYYKGSRYNVQ
EEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA