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The map label for this gene is kdsB

Identifier: 71892154

GI number: 71892154

Start: 455118

End: 455906

Strand: Reverse

Name: kdsB

Synonym: BPEN_387

Alternate gene names: 71892154

Gene position: 455906-455118 (Counterclockwise)

Preceding gene: 71892155

Following gene: 71892153

Centisome position: 57.59

GC content: 34.22

Gene sequence:

>789_bases
ATGAATTTTGTAGTAATTATACCTGTTCGATTTTTTTCGACGCGTTTTCCAGGGAAAGCTTTAGCAGATATTAATGGTAA
ACCTATGATTGTTCGTGTTATGGAAAATGCTTTAGATTCTGGAGCTAATAAAGTAATCATTGCTACAGATAGTTCTTGTA
TAGCGAGAGTCATTGAATCAGAGCAATCCGAAAGTGAGGTATGTTTAACACGATCTACTCATCAGTCAGGTACTGAACGT
CTTGCAGAAGTAGCTATCAATTATAAATTTTCAGATGATCAAATTATCGTACATCTGCAAGGCGATGAACCCTTGCTTTC
TTCTACTATGATTCGTCAAGTAGCAAGTATTTTGTGTTCAATGAGTAGTACTATTTCTATGGCTACGTTAGCAACACCAT
TGAGTTCTTTCAAAGAAGCACGCGATGATAATGTAGTCAAAGTTGTTATAAATATGAATAGCAATGCTCTTTATTTTTCT
CGTTCTATGATTCCATGGAATACAGGAGATTTTGTAAATCATCTAGATAGTAAATTCTCTAAGACATTATTACGTCATAT
TGGTATTTATGCATATCGAGTTAAGTTCTTGCGTCGTTATATTGCATGGACTAAAAGTCCACTGGAACAGATTGAACACC
TTGAACAGCTTCGAGTACTATGGCATGGAGAGGCAATACATGTTTCTGTAATTGATGATGTATTTAATATTAGTGTGGAT
ACTCCAGAGTCATTAAGCCGTGTTAATACTGTATTTAAAAAAAATAAATATGCTACTGTACATAACTGA

Upstream 100 bases:

>100_bases
TAATTTGTAATGTTGATAATTTGGCTTTCCCAATAAGAAAAGGAATCCCGGTTCTCTTAAAAAGAGACGCTCGTAATTTT
ATATTATAGTAGGTAAAAAT

Downstream 100 bases:

>100_bases
TTATGGCAATGTGGATAAACTTTCTTATTAATTACAATACGAATGAATTTAATTATCATTAAAAATAAATACATAGAAGA
ATTTTAAGCGATTTATATTA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNFVVIIPVRFFSTRFPGKALADINGKPMIVRVMENALDSGANKVIIATDSSCIARVIESEQSESEVCLTRSTHQSGTER
LAEVAINYKFSDDQIIVHLQGDEPLLSSTMIRQVASILCSMSSTISMATLATPLSSFKEARDDNVVKVVINMNSNALYFS
RSMIPWNTGDFVNHLDSKFSKTLLRHIGIYAYRVKFLRRYIAWTKSPLEQIEHLEQLRVLWHGEAIHVSVIDDVFNISVD
TPESLSRVNTVFKKNKYATVHN

Sequences:

>Translated_262_residues
MNFVVIIPVRFFSTRFPGKALADINGKPMIVRVMENALDSGANKVIIATDSSCIARVIESEQSESEVCLTRSTHQSGTER
LAEVAINYKFSDDQIIVHLQGDEPLLSSTMIRQVASILCSMSSTISMATLATPLSSFKEARDDNVVKVVINMNSNALYFS
RSMIPWNTGDFVNHLDSKFSKTLLRHIGIYAYRVKFLRRYIAWTKSPLEQIEHLEQLRVLWHGEAIHVSVIDDVFNISVD
TPESLSRVNTVFKKNKYATVHN
>Mature_262_residues
MNFVVIIPVRFFSTRFPGKALADINGKPMIVRVMENALDSGANKVIIATDSSCIARVIESEQSESEVCLTRSTHQSGTER
LAEVAINYKFSDDQIIVHLQGDEPLLSSTMIRQVASILCSMSSTISMATLATPLSSFKEARDDNVVKVVINMNSNALYFS
RSMIPWNTGDFVNHLDSKFSKTLLRHIGIYAYRVKFLRRYIAWTKSPLEQIEHLEQLRVLWHGEAIHVSVIDDVFNISVD
TPESLSRVNTVFKKNKYATVHN

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=253, Percent_Identity=54.1501976284585, Blast_Score=283, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_BLOPB (Q492T2)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277886.1
- ProteinModelPortal:   Q492T2
- SMR:   Q492T2
- STRING:   Q492T2
- GeneID:   3562652
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_387
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   FSRAPLP
- ProtClustDB:   PRK05450
- BioCyc:   CBLO291272:BPEN_387-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 29527; Mature: 29527

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFVVIIPVRFFSTRFPGKALADINGKPMIVRVMENALDSGANKVIIATDSSCIARVIES
CCEEEEEEEHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHC
EQSESEVCLTRSTHQSGTERLAEVAINYKFSDDQIIVHLQGDEPLLSSTMIRQVASILCS
CCCCCCEEEECCCCHHHHHHHHHHHEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHH
MSSTISMATLATPLSSFKEARDDNVVKVVINMNSNALYFSRSMIPWNTGDFVNHLDSKFS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHH
KTLLRHIGIYAYRVKFLRRYIAWTKSPLEQIEHLEQLRVLWHGEAIHVSVIDDVFNISVD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCC
TPESLSRVNTVFKKNKYATVHN
CHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MNFVVIIPVRFFSTRFPGKALADINGKPMIVRVMENALDSGANKVIIATDSSCIARVIES
CCEEEEEEEHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHC
EQSESEVCLTRSTHQSGTERLAEVAINYKFSDDQIIVHLQGDEPLLSSTMIRQVASILCS
CCCCCCEEEECCCCHHHHHHHHHHHEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHH
MSSTISMATLATPLSSFKEARDDNVVKVVINMNSNALYFSRSMIPWNTGDFVNHLDSKFS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHH
KTLLRHIGIYAYRVKFLRRYIAWTKSPLEQIEHLEQLRVLWHGEAIHVSVIDDVFNISVD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCC
TPESLSRVNTVFKKNKYATVHN
CHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA