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The map label for this gene is ribE [H]

Identifier: 71892144

GI number: 71892144

Start: 444000

End: 444623

Strand: Direct

Name: ribE [H]

Synonym: BPEN_377

Alternate gene names: 71892144

Gene position: 444000-444623 (Clockwise)

Preceding gene: 71892142

Following gene: 71892145

Centisome position: 56.09

GC content: 26.6

Gene sequence:

>624_bases
ATGTTTTCAGGTATTATACAAGCTGTTGTTCCAATACATGCAATTTATGAAGTAACCAATTTTAAAACATATACAGTTAT
ATTACCCACATATCTACTCTCAAATTTAAAAATTGGTTGCTCTATATCAAATAATGGATGCTGTTTGACTGTTATTGCCA
TGAAATATAATTTGGTTAGTTTTAATGTAATACATGAAACACTAAAACTAACTAATATAGGTATGTTAAAATTAGGAGAT
TTAACCAATATAGAAAGATCGATCGGTTATCATTCTGAAATTGGTGGGCATTTAATGAGCGGACATATTGACTGCACTGG
AAAAATTATAAAAATAATTACTTCAAAAAACAACAAAATAATATGGTTTAGTATAAAAAAAAAATATCTTAAAAAATATA
TTTTACAGCAAGGATCAATTGGCGTAGATGGAGTAAGTCTTACAGTAAGTAAAATAGTCAATAATTACATACGTATTTGT
TTAACTCCATACACTGCAATACAAACAACGCTTGGTGGAAAAAAAATAGGCAATATAGTAAATATTGAAGTTGACATTAT
TATAAAATCTGCTATAAACAGCTTTGAAAGGACATGGTCTATTATTAATTTGCAAAAAAAATAA

Upstream 100 bases:

>100_bases
GATTTAAAATCATTTCAAAGTGATGTTTAACAAAAAAGAGATACATGCTATAATAGCATTATATATAATTTAAAATGATA
TTAAATAGTATTTGAAAAAT

Downstream 100 bases:

>100_bases
TTAATGTTTATCGACATACGGATTTTATAAACACAAAATAATTATGAGAAATTAAGAAGGATTTACGTTAAATCGTTAAA
TGCCCCATCTACATTAATAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFSGIIQAVVPIHAIYEVTNFKTYTVILPTYLLSNLKIGCSISNNGCCLTVIAMKYNLVSFNVIHETLKLTNIGMLKLGD
LTNIERSIGYHSEIGGHLMSGHIDCTGKIIKIITSKNNKIIWFSIKKKYLKKYILQQGSIGVDGVSLTVSKIVNNYIRIC
LTPYTAIQTTLGGKKIGNIVNIEVDIIIKSAINSFERTWSIINLQKK

Sequences:

>Translated_207_residues
MFSGIIQAVVPIHAIYEVTNFKTYTVILPTYLLSNLKIGCSISNNGCCLTVIAMKYNLVSFNVIHETLKLTNIGMLKLGD
LTNIERSIGYHSEIGGHLMSGHIDCTGKIIKIITSKNNKIIWFSIKKKYLKKYILQQGSIGVDGVSLTVSKIVNNYIRIC
LTPYTAIQTTLGGKKIGNIVNIEVDIIIKSAINSFERTWSIINLQKK
>Mature_207_residues
MFSGIIQAVVPIHAIYEVTNFKTYTVILPTYLLSNLKIGCSISNNGCCLTVIAMKYNLVSFNVIHETLKLTNIGMLKLGD
LTNIERSIGYHSEIGGHLMSGHIDCTGKIIKIITSKNNKIIWFSIKKKYLKKYILQQGSIGVDGVSLTVSKIVNNYIRIC
LTPYTAIQTTLGGKKIGNIVNIEVDIIIKSAINSFERTWSIINLQKK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=197, Percent_Identity=47.2081218274112, Blast_Score=199, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6319733, Length=159, Percent_Identity=32.0754716981132, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23025; Mature: 23025

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGIIQAVVPIHAIYEVTNFKTYTVILPTYLLSNLKIGCSISNNGCCLTVIAMKYNLVS
CCHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCEEEEEECCCCCEEEEEEEEEEEEE
FNVIHETLKLTNIGMLKLGDLTNIERSIGYHSEIGGHLMSGHIDCTGKIIKIITSKNNKI
HHHHHHHHHHHCCCEEEECCCCCHHHHCCCCHHCCCEEEECEEECCCEEEEEEECCCCEE
IWFSIKKKYLKKYILQQGSIGVDGVSLTVSKIVNNYIRICLTPYTAIQTTLGGKKIGNIV
EEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEECCHHHHHHHCCCHHCCCEE
NIEVDIIIKSAINSFERTWSIINLQKK
EEEEEEEEHHHHHHHHHHEEEEEEECC
>Mature Secondary Structure
MFSGIIQAVVPIHAIYEVTNFKTYTVILPTYLLSNLKIGCSISNNGCCLTVIAMKYNLVS
CCHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCEEEEEECCCCCEEEEEEEEEEEEE
FNVIHETLKLTNIGMLKLGDLTNIERSIGYHSEIGGHLMSGHIDCTGKIIKIITSKNNKI
HHHHHHHHHHHCCCEEEECCCCCHHHHCCCCHHCCCEEEECEEECCCEEEEEEECCCCEE
IWFSIKKKYLKKYILQQGSIGVDGVSLTVSKIVNNYIRICLTPYTAIQTTLGGKKIGNIV
EEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEECCHHHHHHHCCCHHCCCEE
NIEVDIIIKSAINSFERTWSIINLQKK
EEEEEEEEHHHHHHHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9022701; 9023191; 9097039; 9278503; 11377200 [H]