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The map label for this gene is pheS

Identifier: 71892134

GI number: 71892134

Start: 431885

End: 432880

Strand: Direct

Name: pheS

Synonym: BPEN_366

Alternate gene names: 71892134

Gene position: 431885-432880 (Clockwise)

Preceding gene: 71892133

Following gene: 71892135

Centisome position: 54.55

GC content: 29.62

Gene sequence:

>996_bases
ATGTCATTAGATCCGGTAAAAAAATTAGTTATACTAGCAAAATCAAATATAATGCAATCTAATAATATGGATGCATTGGA
AGCAATACGTATTAAATTTTTAGGTAAAAAAGGATACCTAAACCAACATATTAAAAATCTTAATGATACCTCATTAGATA
TTAAACCTAAATTAGGAGCAGCTATTAATCAAGCTAAAGAAGACATATACACATTACTTATTGAACGAAAAAATATTTTA
CAATCAAAAAATATAAAAAATACCCTGATCACTGATACATTAGATGTTACTTTACCAGGACGGTTATCAGATATAGGGAC
ACATCATCCAATAACAAGCACTATAAAACGCATGAAGATTTTTTTTAACACTTTAGGTTTCTCCGTAATACATGGTCCAG
AAATTGAAGATGATTATTTTAATTTCGACGCCTTAAACATTCCCAAGTATCATCCTTCCAGAGATGAACATGATACCTTT
TGGTTTGACGAAAAACGCCTACTTCGTACGCACACTTCCGGCGTTCAAATACGTGCTATGATTAATAAAACTCCCCCAAT
TCGTATCATTTCTTTTGGACGAGTATATCGCAAAGATTACGATCAACATCATACACCTATGTTTCATCAAATGGAAGGAT
TAATAGTAGATTCTAATGTTAACTTCAGTTATCTAAAAAAAATATTATATGATTTTTTGTATAATTTTTTTGAAACAGAT
ATTATTTTGCGTTTTAGACCGTCTTATTTTCCATTTACAGAACCATCGGCAGAAATAGATGTAATGAAAAAACAAGAAAC
TGGAAATTGGTTAGAACTTTTAGGATGCGGTATGGTACATCCCAAAATATTACATCATGTTGATATTGATACAGAAAAAT
TTTCAGGATTTGCCTTTGGAATAGGAATAGAACGATTAACAATGCTACAATACAATATTGACGATATACGAGTTTTTTTC
AAAAATGATTTACAATTTCTTGATCAATTTAAATAA

Upstream 100 bases:

>100_bases
TTAACACAGTTAGTCAAATTGACATATCATACAATTATTAATTATATATATTAAATTAATCAAGACAGCACTATATGAAT
ATAGTGACACGAGGATATTT

Downstream 100 bases:

>100_bases
TATAAGGATTTAAATGAAATTTAGTGAAATGTGGATACGCGAATGGATAAATCCACCTATTAGTAGCATTGAATTAGCTG
ATCAATTAACCATGGCTGGA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSLDPVKKLVILAKSNIMQSNNMDALEAIRIKFLGKKGYLNQHIKNLNDTSLDIKPKLGAAINQAKEDIYTLLIERKNIL
QSKNIKNTLITDTLDVTLPGRLSDIGTHHPITSTIKRMKIFFNTLGFSVIHGPEIEDDYFNFDALNIPKYHPSRDEHDTF
WFDEKRLLRTHTSGVQIRAMINKTPPIRIISFGRVYRKDYDQHHTPMFHQMEGLIVDSNVNFSYLKKILYDFLYNFFETD
IILRFRPSYFPFTEPSAEIDVMKKQETGNWLELLGCGMVHPKILHHVDIDTEKFSGFAFGIGIERLTMLQYNIDDIRVFF
KNDLQFLDQFK

Sequences:

>Translated_331_residues
MSLDPVKKLVILAKSNIMQSNNMDALEAIRIKFLGKKGYLNQHIKNLNDTSLDIKPKLGAAINQAKEDIYTLLIERKNIL
QSKNIKNTLITDTLDVTLPGRLSDIGTHHPITSTIKRMKIFFNTLGFSVIHGPEIEDDYFNFDALNIPKYHPSRDEHDTF
WFDEKRLLRTHTSGVQIRAMINKTPPIRIISFGRVYRKDYDQHHTPMFHQMEGLIVDSNVNFSYLKKILYDFLYNFFETD
IILRFRPSYFPFTEPSAEIDVMKKQETGNWLELLGCGMVHPKILHHVDIDTEKFSGFAFGIGIERLTMLQYNIDDIRVFF
KNDLQFLDQFK
>Mature_330_residues
SLDPVKKLVILAKSNIMQSNNMDALEAIRIKFLGKKGYLNQHIKNLNDTSLDIKPKLGAAINQAKEDIYTLLIERKNILQ
SKNIKNTLITDTLDVTLPGRLSDIGTHHPITSTIKRMKIFFNTLGFSVIHGPEIEDDYFNFDALNIPKYHPSRDEHDTFW
FDEKRLLRTHTSGVQIRAMINKTPPIRIISFGRVYRKDYDQHHTPMFHQMEGLIVDSNVNFSYLKKILYDFLYNFFETDI
ILRFRPSYFPFTEPSAEIDVMKKQETGNWLELLGCGMVHPKILHHVDIDTEKFSGFAFGIGIERLTMLQYNIDDIRVFFK
NDLQFLDQFK

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily

Homologues:

Organism=Homo sapiens, GI4758340, Length=276, Percent_Identity=32.2463768115942, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI5729820, Length=281, Percent_Identity=30.6049822064057, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1788007, Length=326, Percent_Identity=59.2024539877301, Blast_Score=414, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI32566635, Length=240, Percent_Identity=35.4166666666667, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32563657, Length=270, Percent_Identity=28.8888888888889, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17508957, Length=270, Percent_Identity=28.8888888888889, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321087, Length=259, Percent_Identity=28.957528957529, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6325304, Length=91, Percent_Identity=38.4615384615385, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17137424, Length=310, Percent_Identity=29.3548387096774, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI18858079, Length=273, Percent_Identity=28.9377289377289, Blast_Score=104, Evalue=7e-23,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFA_BLOPB (Q492V1)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277866.1
- ProteinModelPortal:   Q492V1
- SMR:   Q492V1
- STRING:   Q492V1
- GeneID:   3563040
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_366
- eggNOG:   COG0016
- HOGENOM:   HBG284353
- OMA:   FRASYFP
- ProtClustDB:   PRK00488
- BioCyc:   CBLO291272:BPEN_366-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00281
- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978
- PANTHER:   PTHR11538
- TIGRFAMs:   TIGR00468

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d; SSF46589 tRNA_binding_arm

EC number: =6.1.1.20

Molecular weight: Translated: 38623; Mature: 38492

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDPVKKLVILAKSNIMQSNNMDALEAIRIKFLGKKGYLNQHIKNLNDTSLDIKPKLGA
CCCCHHHHHHHHHHHHHCCCCCCCHHHHEEHHEECCCCHHHHHHCCCCCCCEEECCCHHH
AINQAKEDIYTLLIERKNILQSKNIKNTLITDTLDVTLPGRLSDIGTHHPITSTIKRMKI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECEEEEEECCCHHHCCCCCCHHHHHHHHHH
FFNTLGFSVIHGPEIEDDYFNFDALNIPKYHPSRDEHDTFWFDEKRLLRTHTSGVQIRAM
HHHHHCCEEEECCCCCCCCCCCCEECCCCCCCCCCCCCCEEECCHHHHHHCCCCEEEEEE
INKTPPIRIISFGRVYRKDYDQHHTPMFHQMEGLIVDSNVNFSYLKKILYDFLYNFFETD
ECCCCCEEEEECHHHHHHHCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCC
IILRFRPSYFPFTEPSAEIDVMKKQETGNWLELLGCGMVHPKILHHVDIDTEKFSGFAFG
EEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCHHHHHEECCCCHHCCCEEEE
IGIERLTMLQYNIDDIRVFFKNDLQFLDQFK
ECHHHEEEEEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLDPVKKLVILAKSNIMQSNNMDALEAIRIKFLGKKGYLNQHIKNLNDTSLDIKPKLGA
CCCHHHHHHHHHHHHHCCCCCCCHHHHEEHHEECCCCHHHHHHCCCCCCCEEECCCHHH
AINQAKEDIYTLLIERKNILQSKNIKNTLITDTLDVTLPGRLSDIGTHHPITSTIKRMKI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECEEEEEECCCHHHCCCCCCHHHHHHHHHH
FFNTLGFSVIHGPEIEDDYFNFDALNIPKYHPSRDEHDTFWFDEKRLLRTHTSGVQIRAM
HHHHHCCEEEECCCCCCCCCCCCEECCCCCCCCCCCCCCEEECCHHHHHHCCCCEEEEEE
INKTPPIRIISFGRVYRKDYDQHHTPMFHQMEGLIVDSNVNFSYLKKILYDFLYNFFETD
ECCCCCEEEEECHHHHHHHCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCC
IILRFRPSYFPFTEPSAEIDVMKKQETGNWLELLGCGMVHPKILHHVDIDTEKFSGFAFG
EEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCHHHHHEECCCCHHCCCEEEE
IGIERLTMLQYNIDDIRVFFKNDLQFLDQFK
ECHHHEEEEEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA