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The map label for this gene is lolB [H]

Identifier: 71892126

GI number: 71892126

Start: 422670

End: 423287

Strand: Reverse

Name: lolB [H]

Synonym: BPEN_358

Alternate gene names: 71892126

Gene position: 423287-422670 (Counterclockwise)

Preceding gene: 71892143

Following gene: 71892125

Centisome position: 53.47

GC content: 25.73

Gene sequence:

>618_bases
ATGTGTCAACATAGGTGTTTTAGAGTGTTTGGTATAGTGATGTTGATCTGTGTTTCCTGCGTTTATCATCATAATTTTGG
TTTGTATGAAGATAAATTGGTATATATGTGGAATAATCATAAGAAATCAATATCCCGGATATTTTATTATCAAACACAAG
GTACTATTATTTATTCAGTTAATCACCAAAAGAAGATGCATTTTAGGTTTATTTGGATTCATAATAATGATAATAATTAT
TGCATGAAATTATTTAATATTTTAGGATTAACTATAATTTCTATATCTGTAGAAAATGGAGTTGTTTGTATTTTAAATGG
TATAATTTATCAAAATAATGATTTTAAAAATGAAATACAAAAATGGATTGTGGATTTCAACTATTTTTTAAAACAATTAC
AACAATGGATACTTGGATTACCTGGTAGTAATGCAGAATATAATCTGAATGCTATAGGCTGCTTATCTCATGTAAATTGT
TGCTATGGCAATAAAAATATATCTATATATTATCGTCATTACTATACTAATAGTATACCAATTTTGCCTAAAGTCTTGGA
TGCGCATTATGATCAACATCATATTAAGCTAATAATTAATAATTGGAATGTACGATGA

Upstream 100 bases:

>100_bases
TTAGCAGATAGATGATTACATTTAAGATGTGAATTTTAATATGAATAAAATAAATAAAATTTATTTTTTAGAAGATAGTT
TTTTAAATTTTAATATTTAA

Downstream 100 bases:

>100_bases
ATTATCAATGGCCCTCTCCAGGAAAACTTAATTTATTTTTATACGTAACTGGATGTCGTGCAGACGGTTACCATTACTTA
CAGACATTGTTTCAGTTGAT

Product: outer membrane lipoprotein precursor

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MCQHRCFRVFGIVMLICVSCVYHHNFGLYEDKLVYMWNNHKKSISRIFYYQTQGTIIYSVNHQKKMHFRFIWIHNNDNNY
CMKLFNILGLTIISISVENGVVCILNGIIYQNNDFKNEIQKWIVDFNYFLKQLQQWILGLPGSNAEYNLNAIGCLSHVNC
CYGNKNISIYYRHYYTNSIPILPKVLDAHYDQHHIKLIINNWNVR

Sequences:

>Translated_205_residues
MCQHRCFRVFGIVMLICVSCVYHHNFGLYEDKLVYMWNNHKKSISRIFYYQTQGTIIYSVNHQKKMHFRFIWIHNNDNNY
CMKLFNILGLTIISISVENGVVCILNGIIYQNNDFKNEIQKWIVDFNYFLKQLQQWILGLPGSNAEYNLNAIGCLSHVNC
CYGNKNISIYYRHYYTNSIPILPKVLDAHYDQHHIKLIINNWNVR
>Mature_205_residues
MCQHRCFRVFGIVMLICVSCVYHHNFGLYEDKLVYMWNNHKKSISRIFYYQTQGTIIYSVNHQKKMHFRFIWIHNNDNNY
CMKLFNILGLTIISISVENGVVCILNGIIYQNNDFKNEIQKWIVDFNYFLKQLQQWILGLPGSNAEYNLNAIGCLSHVNC
CYGNKNISIYYRHYYTNSIPILPKVLDAHYDQHHIKLIINNWNVR

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

Organism=Escherichia coli, GI1787460, Length=203, Percent_Identity=28.0788177339901, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 24470; Mature: 24470

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCQHRCFRVFGIVMLICVSCVYHHNFGLYEDKLVYMWNNHKKSISRIFYYQTQGTIIYSV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEEEECCEEEEEE
NHQKKMHFRFIWIHNNDNNYCMKLFNILGLTIISISVENGVVCILNGIIYQNNDFKNEIQ
CCCCEEEEEEEEEEECCCHHHHHHHHHHCEEEEEEEECCCEEEEEEEEEEECCCHHHHHH
KWIVDFNYFLKQLQQWILGLPGSNAEYNLNAIGCLSHVNCCYGNKNISIYYRHYYTNSIP
HHHHHHHHHHHHHHHHHHCCCCCCCEEECEEEEHHHHCEEEECCCCEEEEEEEEECCCCC
ILPKVLDAHYDQHHIKLIINNWNVR
CHHHHHHCCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MCQHRCFRVFGIVMLICVSCVYHHNFGLYEDKLVYMWNNHKKSISRIFYYQTQGTIIYSV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEEEECCEEEEEE
NHQKKMHFRFIWIHNNDNNYCMKLFNILGLTIISISVENGVVCILNGIIYQNNDFKNEIQ
CCCCEEEEEEEEEEECCCHHHHHHHHHHCEEEEEEEECCCEEEEEEEEEEECCCHHHHHH
KWIVDFNYFLKQLQQWILGLPGSNAEYNLNAIGCLSHVNCCYGNKNISIYYRHYYTNSIP
HHHHHHHHHHHHHHHHHHCCCCCCCEEECEEEEHHHHCEEEECCCCEEEEEEEEECCCCC
ILPKVLDAHYDQHHIKLIINNWNVR
CHHHHHHCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA