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The map label for this gene is guaA [C]

Identifier: 68536053

GI number: 68536053

Start: 1155025

End: 1155768

Strand: Direct

Name: guaA [C]

Synonym: jk0976

Alternate gene names: 68536053

Gene position: 1155025-1155768 (Clockwise)

Preceding gene: 68536052

Following gene: 68536055

Centisome position: 46.9

GC content: 64.78

Gene sequence:

>744_bases
GTGACTTTCGTACTGCTAAGCCCCCGCAGCGGCGCCGAGGTGCTCGCCGCGGAATACGCCGACTTCCTCAGCTACAGCGG
CCTCACCCCCGCCGAGCTCGAACAGCGACCGCTGGATAACCCCGGCGCCGACCTGGGAAGTTTCGACGGCGTGGAGGGCG
TGTTTATCGGCGGCTCGCCGTTTACGATCACCCGCCCGGTCGACGTGGAATGGCAAGAAGCGATCTCGCAGAAGCTGGTG
GATTTCATCCAGGTCGAATCGGAGCGGCAGCGCTTCGGCATCTTCTCCACCTGCTACGGCACCTCCATGCTGGCGCACTA
CCTAGACGGCGAGGTCAACAGTAAGTACTCGGAATCGGCGGGTACCAGCGAGGTTTCTCTTACTGACGCCGGGCGCGTCG
ACCCCATCACGGGTGCGCTCCCCGACCGCTTCACTGCGCTGACGGGCCACAAGGATTCCGTGGTGCGCGTGCCCGCGGAG
GCCACCCTGCTGGCCACCGGCGAAACTTGCCCGGTGCAGATCTACCGCTACCGCGAAAACGTCTGGACCAGCCAATTCCA
CCCGGAGATGGATGCTGCCGGTATCACCCGGCGCCTCAGCTTCTACGAGGACGAGGGTTACTGCGACCCCGCGGAGATCG
CGGAGACTTACGCACGCTTCGAGGGGCAGGATACGGCGGCGGCGAATTCGTTGCTGCGGTGCTTTGTGGAGCACTCCCGC
AGCTCGCTGGGGATGGTGAGCTAG

Upstream 100 bases:

>100_bases
GACAAGAAGATCGACAGTGCGCACGAGTTGCTGCAAAAGTTGGGGCGCGCGGGCGTCAAAAAATAGTAAATAGACCAAGC
GGTCTGTTACAGTAACGAAT

Downstream 100 bases:

>100_bases
CTGGCTGGGCTAGGCCAGCTCGACGATCTCCATGTACTCATCGCTCCACAGGTCTTCCACGCCGTCGGGGAGCACGATCA
CCCGCTCGGGCTCCAGGGCC

Product: glutamine amidotransferase

Products: AMP; diphosphate; GMP; L-glutamate

Alternate protein names: Glutamine Amidotransferase Class-I; Amino Transferase; Class I Glutamine Amidotransferase Family Protein; GMP Synthase; Glutamine Amidotransferase Class I; Class I Glutamine Amidotransferase; GMP Synthase Family Protein; Glutamine Amidotransferase Protein; Glutamine-Hydrolyzing GMP Synthase

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTFVLLSPRSGAEVLAAEYADFLSYSGLTPAELEQRPLDNPGADLGSFDGVEGVFIGGSPFTITRPVDVEWQEAISQKLV
DFIQVESERQRFGIFSTCYGTSMLAHYLDGEVNSKYSESAGTSEVSLTDAGRVDPITGALPDRFTALTGHKDSVVRVPAE
ATLLATGETCPVQIYRYRENVWTSQFHPEMDAAGITRRLSFYEDEGYCDPAEIAETYARFEGQDTAAANSLLRCFVEHSR
SSLGMVS

Sequences:

>Translated_247_residues
MTFVLLSPRSGAEVLAAEYADFLSYSGLTPAELEQRPLDNPGADLGSFDGVEGVFIGGSPFTITRPVDVEWQEAISQKLV
DFIQVESERQRFGIFSTCYGTSMLAHYLDGEVNSKYSESAGTSEVSLTDAGRVDPITGALPDRFTALTGHKDSVVRVPAE
ATLLATGETCPVQIYRYRENVWTSQFHPEMDAAGITRRLSFYEDEGYCDPAEIAETYARFEGQDTAAANSLLRCFVEHSR
SSLGMVS
>Mature_246_residues
TFVLLSPRSGAEVLAAEYADFLSYSGLTPAELEQRPLDNPGADLGSFDGVEGVFIGGSPFTITRPVDVEWQEAISQKLVD
FIQVESERQRFGIFSTCYGTSMLAHYLDGEVNSKYSESAGTSEVSLTDAGRVDPITGALPDRFTALTGHKDSVVRVPAEA
TLLATGETCPVQIYRYRENVWTSQFHPEMDAAGITRRLSFYEDEGYCDPAEIAETYARFEGQDTAAANSLLRCFVEHSRS
SLGMVS

Specific function: Catalyzes The Synthesis Of Gmp From Xmp. [C]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.3.5.2

Molecular weight: Translated: 27027; Mature: 26896

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFVLLSPRSGAEVLAAEYADFLSYSGLTPAELEQRPLDNPGADLGSFDGVEGVFIGGSP
CEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCC
FTITRPVDVEWQEAISQKLVDFIQVESERQRFGIFSTCYGTSMLAHYLDGEVNSKYSESA
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCC
GTSEVSLTDAGRVDPITGALPDRFTALTGHKDSVVRVPAEATLLATGETCPVQIYRYREN
CCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCEEECCCCEEEEECCCCCCEEEEEEHHH
VWTSQFHPEMDAAGITRRLSFYEDEGYCDPAEIAETYARFEGQDTAAANSLLRCFVEHSR
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SSLGMVS
CCCCCCC
>Mature Secondary Structure 
TFVLLSPRSGAEVLAAEYADFLSYSGLTPAELEQRPLDNPGADLGSFDGVEGVFIGGSP
EEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCC
FTITRPVDVEWQEAISQKLVDFIQVESERQRFGIFSTCYGTSMLAHYLDGEVNSKYSESA
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCC
GTSEVSLTDAGRVDPITGALPDRFTALTGHKDSVVRVPAEATLLATGETCPVQIYRYREN
CCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCEEECCCCEEEEECCCCCCEEEEEEHHH
VWTSQFHPEMDAAGITRRLSFYEDEGYCDPAEIAETYARFEGQDTAAANSLLRCFVEHSR
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SSLGMVS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.35 {8-azaXMP}} 1 {NH4+}} 0.42 {6-thioXMP}} 0.53 {ATP}} 2 {1-ribosyl-4,6-dihydroxypyrazolo[3,4-d]-pyrimidine} 0.058 {XMP}} 0.029 {XMP}} [C]

Substrates: ATP; xanthosine 5'-phosphate; L-glutamine; H2O

Specific reaction: ATP + xanthosine 5'-phosphate + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate

General reaction: Amination [C]

Inhibitor: 1, N6-Ethenoadenosine; 1-Methyl adenosine 5'-phosphate 5'-phosphate; 2', 3'-Dihydroadenosine; 2'-Deoxyadenosine; 2, 6-Diaminopurine ribonucleoside; 2-Amino-6-methyl thiopurine ribonucleoside; 2-Fluoroadenosine; 3'-Deoxyadenosine; 5'-Azido-5'-deoxyadenosin

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA