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The map label for this gene is argC [H]

Identifier: 68535916

GI number: 68535916

Start: 1002338

End: 1003363

Strand: Direct

Name: argC [H]

Synonym: jk0841

Alternate gene names: 68535916

Gene position: 1002338-1003363 (Clockwise)

Preceding gene: 68535915

Following gene: 68535917

Centisome position: 40.7

GC content: 66.57

Gene sequence:

>1026_bases
ATGTTGAAAATTGCAGTAGCAGGCGCCAGTGGGTACGCGGGTGGTGAGGCTCTTCGCCTCCTATTGAATCACCCCGGCTA
CGGCGTGGACTTCGAAATCGGTTCGCTGACCGGCGGTTCCAACGCGGGCACGCGATTCGGCGAACTCAACCCCGGGCTGC
CCGCCCTGGCGGATCGCGTTCTCGAAGAGACGACGGAGGATGTTCTCCGCGGGCACGATGCTGCAATCCTGGCCCTCCCG
CACGGGGTGTCCGCCGCCCTGGATCTGCCGGAATCCATGAAGATCGTGGACTGTGGCGCGGACTACCGCCTGAAGAACGC
CAACCACTGGGCCCGCTTCTACGGCACCCCGCACGCCGGCACCCGCACCTACGGCATCCCGGAGATGCCGGGGCGCCGGG
AGGAGATCGCGGCCACCAACTACGTCGCCGCCCCCGGTTGCTTCCCGACCGGCGCCACGATGGCCCTCATGCCCGCTATC
GCCAGCGGCCTGATGGCCCCGCAGATCAGCGTGGTTTCCGTCACCGGCACCACCGGCGCTGGCAAGAAGGCCGCCGTGAA
CCTGCTGGGTTCGGAGACCATGGGGAACTTGCGCGCCTATGGCGTGGGCACCCACCGCCACGCGCCGGAGATCAAGCAGA
GTGTCGAGGAGCTGCTGGCTCCCGGCTACTCCTCGGACGACGTCCACGTGACCTTCACCCCGGTGCTGGCCCCGCTGACC
CGCGGCATCCTCACCACCGTCACCGCCCCCGCGCGTGGCCAGGCTCGCGATATCCGCCGTGCCTACGAGAAGTTCTGCGC
CAACGAGCCCTTCCTCCACCTGCTGCCGGAGGGCCAGCAGCCGGAGGTGAAGAGCGTCGTCGGCTCCAACATGGTGCACA
TCCAAGTAGAAGTCGCCGATGGCATGGTCATAGCTACCAGCGCCATCGATAACCTCACCAAAGGCACCGCAGGTGCCGCC
ATCCAATGCCTCAACCTGATGTTCGGTTGGGAAGAAAACGCGGGACTCCCGCAGACGGGGCTCTGA

Upstream 100 bases:

>100_bases
CGCCACCGAGAAGGTGGGTGCGCAGCTCCGCGCCTAACTGCATAATTCCCACAAATCTGAATAATTTGCAATTTTGGTAC
TAGTAGGGCAGAATCGTCCT

Downstream 100 bases:

>100_bases
TTCAAAACTATGACCAGCGCAGACAAGAACAATCCGGATACCAGCACTGCCCAGGGATCCTCTGCGGACCTCGGTGTGAC
CGTTCCCAAGGGCTTTAGCG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MLKIAVAGASGYAGGEALRLLLNHPGYGVDFEIGSLTGGSNAGTRFGELNPGLPALADRVLEETTEDVLRGHDAAILALP
HGVSAALDLPESMKIVDCGADYRLKNANHWARFYGTPHAGTRTYGIPEMPGRREEIAATNYVAAPGCFPTGATMALMPAI
ASGLMAPQISVVSVTGTTGAGKKAAVNLLGSETMGNLRAYGVGTHRHAPEIKQSVEELLAPGYSSDDVHVTFTPVLAPLT
RGILTTVTAPARGQARDIRRAYEKFCANEPFLHLLPEGQQPEVKSVVGSNMVHIQVEVADGMVIATSAIDNLTKGTAGAA
IQCLNLMFGWEENAGLPQTGL

Sequences:

>Translated_341_residues
MLKIAVAGASGYAGGEALRLLLNHPGYGVDFEIGSLTGGSNAGTRFGELNPGLPALADRVLEETTEDVLRGHDAAILALP
HGVSAALDLPESMKIVDCGADYRLKNANHWARFYGTPHAGTRTYGIPEMPGRREEIAATNYVAAPGCFPTGATMALMPAI
ASGLMAPQISVVSVTGTTGAGKKAAVNLLGSETMGNLRAYGVGTHRHAPEIKQSVEELLAPGYSSDDVHVTFTPVLAPLT
RGILTTVTAPARGQARDIRRAYEKFCANEPFLHLLPEGQQPEVKSVVGSNMVHIQVEVADGMVIATSAIDNLTKGTAGAA
IQCLNLMFGWEENAGLPQTGL
>Mature_341_residues
MLKIAVAGASGYAGGEALRLLLNHPGYGVDFEIGSLTGGSNAGTRFGELNPGLPALADRVLEETTEDVLRGHDAAILALP
HGVSAALDLPESMKIVDCGADYRLKNANHWARFYGTPHAGTRTYGIPEMPGRREEIAATNYVAAPGCFPTGATMALMPAI
ASGLMAPQISVVSVTGTTGAGKKAAVNLLGSETMGNLRAYGVGTHRHAPEIKQSVEELLAPGYSSDDVHVTFTPVLAPLT
RGILTTVTAPARGQARDIRRAYEKFCANEPFLHLLPEGQQPEVKSVVGSNMVHIQVEVADGMVIATSAIDNLTKGTAGAA
IQCLNLMFGWEENAGLPQTGL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=354, Percent_Identity=32.4858757062147, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320913, Length=356, Percent_Identity=26.9662921348315, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 35664; Mature: 35664

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIAVAGASGYAGGEALRLLLNHPGYGVDFEIGSLTGGSNAGTRFGELNPGLPALADRV
CEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
LEETTEDVLRGHDAAILALPHGVSAALDLPESMKIVDCGADYRLKNANHWARFYGTPHAG
HHHHHHHHHCCCCEEEEEECCCCHHHHCCCCCCEEEECCCCCEECCCCCEEEEECCCCCC
TRTYGIPEMPGRREEIAATNYVAAPGCFPTGATMALMPAIASGLMAPQISVVSVTGTTGA
CCCCCCCCCCCCHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCC
GKKAAVNLLGSETMGNLRAYGVGTHRHAPEIKQSVEELLAPGYSSDDVHVTFTPVLAPLT
CCHHEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHH
RGILTTVTAPARGQARDIRRAYEKFCANEPFLHLLPEGQQPEVKSVVGSNMVHIQVEVAD
HHHHHEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCEEEEEEEECC
GMVIATSAIDNLTKGTAGAAIQCLNLMFGWEENAGLPQTGL
CEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLKIAVAGASGYAGGEALRLLLNHPGYGVDFEIGSLTGGSNAGTRFGELNPGLPALADRV
CEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
LEETTEDVLRGHDAAILALPHGVSAALDLPESMKIVDCGADYRLKNANHWARFYGTPHAG
HHHHHHHHHCCCCEEEEEECCCCHHHHCCCCCCEEEECCCCCEECCCCCEEEEECCCCCC
TRTYGIPEMPGRREEIAATNYVAAPGCFPTGATMALMPAIASGLMAPQISVVSVTGTTGA
CCCCCCCCCCCCHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCC
GKKAAVNLLGSETMGNLRAYGVGTHRHAPEIKQSVEELLAPGYSSDDVHVTFTPVLAPLT
CCHHEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHH
RGILTTVTAPARGQARDIRRAYEKFCANEPFLHLLPEGQQPEVKSVVGSNMVHIQVEVAD
HHHHHEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCEEEEEEEECC
GMVIATSAIDNLTKGTAGAAIQCLNLMFGWEENAGLPQTGL
CEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA