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The map label for this gene is pheS

Identifier: 68535914

GI number: 68535914

Start: 998607

End: 999662

Strand: Direct

Name: pheS

Synonym: jk0839

Alternate gene names: 68535914

Gene position: 998607-999662 (Clockwise)

Preceding gene: 68535913

Following gene: 68535915

Centisome position: 40.55

GC content: 66.86

Gene sequence:

>1056_bases
GTGACGGATTCCGCGGACACTCCCCAGGTAGAGCTTTCGGAGCAGGGGCTCAACGCCGCAGCAGACGCAGCCGAGAAGGC
CTTTGCCGAGGCTGCAAATCTGGAGGAACTGGCGGCCGCTCGCCGCGAGCACCTGGGCGACGATGCCCCCATTCCGGCCG
CCCGCCGTAGCCTGGGCAGCCTGCCGAAGGATCAGCGCAAGGACGCTGGTCGCCTGGTGAATATGGCGCGGGGCCGCGTC
GAAAAGCGCTTCGCCCAGGTTAAGGCCGAGCTCGAGCGTAAGCGCAACGAGGAAGTCCTGCGCGCCGAGCGCATCGACGT
CACCGAGCCGACCACCCGCGGCCAGCGCGGCGCCCAGCATCCGATCACCATCCTGTCCGAGCAGATCGCCGACATCTTCG
TCGGCATGGGCTGGGAGATCGCCGATGGTCCGGAGGTTGAGGCCGAGTACTTCAACTTCGACTCCCTGAATTTCATCCCA
GACCACCCCGCGCGCACGCTACAGGACACCTTCCACATCGCTCCGGAGGGTTCCGGCCAGGTGCTGCGCACCCACACTTC
TCCGGTGCAGATGCGCACGATGCTTTCCCGCGACCTGCCGATATACATCGCCTGCCCGGGTCGCGTGTTCCGCACCGATG
AGCTGGACGCCACCCACACCCCCGTGTTCCACCAGGTCGAAGGCCTGGCCGTGGATAAGGGGCTGACGATGGCGCACCTG
AAGGGAACGCTGGACCACCTGGCCAAGACGCTGTTCGGCGAGGAAGCCAAGACCCGCATCCGTCCGAACTACTTCCCGTT
CACCGAGCCCTCCGCAGAGGTGGATGTCTGGTTCGCCGACAAGAAGGGCGGCGCCGGCTGGATCGAGTGGGGCGGCTGCG
GCATGGTCAACCCGAACGTCCTGATCGCCGCGGGCGTGGATCCGGAGGAGTACTCCGGCTTCGCCTTCGGCATGGGCATC
GAGCGCACCCTGCAGTTCCGCAACGGCCTGCCCGACATGCGCGACATGGTGGAGGGCGATGTGCGCTTCACCCTGCCGTT
CGGCGTGCGCCGCTAG

Upstream 100 bases:

>100_bases
AGCAGTCGAAGACTGATAGCCCCAACTCGGTGCGGCAGTGGGCCAGCCGGGTATTATTAACGAGGTTAAGCCGTGCACGT
AGATAGAGGAGCGCACTGAA

Downstream 100 bases:

>100_bases
AGAAACTTCACCCCACCCCATCTAAAGCCCCAATCAAGGATCTTTCGAAAATCATGCTTATTTCCCAGTCGTGGCTGACC
CGAATCCTGCAGACCTCCAA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTDSADTPQVELSEQGLNAAADAAEKAFAEAANLEELAAARREHLGDDAPIPAARRSLGSLPKDQRKDAGRLVNMARGRV
EKRFAQVKAELERKRNEEVLRAERIDVTEPTTRGQRGAQHPITILSEQIADIFVGMGWEIADGPEVEAEYFNFDSLNFIP
DHPARTLQDTFHIAPEGSGQVLRTHTSPVQMRTMLSRDLPIYIACPGRVFRTDELDATHTPVFHQVEGLAVDKGLTMAHL
KGTLDHLAKTLFGEEAKTRIRPNYFPFTEPSAEVDVWFADKKGGAGWIEWGGCGMVNPNVLIAAGVDPEEYSGFAFGMGI
ERTLQFRNGLPDMRDMVEGDVRFTLPFGVRR

Sequences:

>Translated_351_residues
MTDSADTPQVELSEQGLNAAADAAEKAFAEAANLEELAAARREHLGDDAPIPAARRSLGSLPKDQRKDAGRLVNMARGRV
EKRFAQVKAELERKRNEEVLRAERIDVTEPTTRGQRGAQHPITILSEQIADIFVGMGWEIADGPEVEAEYFNFDSLNFIP
DHPARTLQDTFHIAPEGSGQVLRTHTSPVQMRTMLSRDLPIYIACPGRVFRTDELDATHTPVFHQVEGLAVDKGLTMAHL
KGTLDHLAKTLFGEEAKTRIRPNYFPFTEPSAEVDVWFADKKGGAGWIEWGGCGMVNPNVLIAAGVDPEEYSGFAFGMGI
ERTLQFRNGLPDMRDMVEGDVRFTLPFGVRR
>Mature_350_residues
TDSADTPQVELSEQGLNAAADAAEKAFAEAANLEELAAARREHLGDDAPIPAARRSLGSLPKDQRKDAGRLVNMARGRVE
KRFAQVKAELERKRNEEVLRAERIDVTEPTTRGQRGAQHPITILSEQIADIFVGMGWEIADGPEVEAEYFNFDSLNFIPD
HPARTLQDTFHIAPEGSGQVLRTHTSPVQMRTMLSRDLPIYIACPGRVFRTDELDATHTPVFHQVEGLAVDKGLTMAHLK
GTLDHLAKTLFGEEAKTRIRPNYFPFTEPSAEVDVWFADKKGGAGWIEWGGCGMVNPNVLIAAGVDPEEYSGFAFGMGIE
RTLQFRNGLPDMRDMVEGDVRFTLPFGVRR

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily

Homologues:

Organism=Homo sapiens, GI4758340, Length=273, Percent_Identity=30.4029304029304, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI5729820, Length=275, Percent_Identity=28.7272727272727, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788007, Length=325, Percent_Identity=44.9230769230769, Blast_Score=271, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI17508957, Length=273, Percent_Identity=30.4029304029304, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563657, Length=273, Percent_Identity=30.4029304029304, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32566635, Length=246, Percent_Identity=32.520325203252, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321087, Length=264, Percent_Identity=30.3030303030303, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325304, Length=276, Percent_Identity=27.536231884058, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18858079, Length=266, Percent_Identity=31.9548872180451, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17137424, Length=287, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFA_CORJK (Q4JW06)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250619.1
- ProteinModelPortal:   Q4JW06
- SMR:   Q4JW06
- STRING:   Q4JW06
- GeneID:   3432398
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0839
- NMPDR:   fig|306537.3.peg.2031
- eggNOG:   COG0016
- HOGENOM:   HBG284353
- OMA:   FRASYFP
- ProtClustDB:   PRK00488
- BioCyc:   CJEI306537:JK0839-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00281
- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978
- PANTHER:   PTHR11538
- TIGRFAMs:   TIGR00468

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d; SSF46589 tRNA_binding_arm

EC number: =6.1.1.20

Molecular weight: Translated: 38866; Mature: 38735

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSADTPQVELSEQGLNAAADAAEKAFAEAANLEELAAARREHLGDDAPIPAARRSLGS
CCCCCCCCCEEEHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHCC
LPKDQRKDAGRLVNMARGRVEKRFAQVKAELERKRNEEVLRAERIDVTEPTTRGQRGAQH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PITILSEQIADIFVGMGWEIADGPEVEAEYFNFDSLNFIPDHPARTLQDTFHIAPEGSGQ
CHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHEEECCCCCCC
VLRTHTSPVQMRTMLSRDLPIYIACPGRVFRTDELDATHTPVFHQVEGLAVDKGLTMAHL
EEEECCCHHHHHHHHHCCCCEEEECCCCEEECCCCCCCCCCHHHHHCCEEECCCCHHHHH
KGTLDHLAKTLFGEEAKTRIRPNYFPFTEPSAEVDVWFADKKGGAGWIEWGGCGMVNPNV
HHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCE
LIAAGVDPEEYSGFAFGMGIERTLQFRNGLPDMRDMVEGDVRFTLPFGVRR
EEEECCCHHHHCCEEECCCHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure 
TDSADTPQVELSEQGLNAAADAAEKAFAEAANLEELAAARREHLGDDAPIPAARRSLGS
CCCCCCCCEEEHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHCC
LPKDQRKDAGRLVNMARGRVEKRFAQVKAELERKRNEEVLRAERIDVTEPTTRGQRGAQH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PITILSEQIADIFVGMGWEIADGPEVEAEYFNFDSLNFIPDHPARTLQDTFHIAPEGSGQ
CHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHEEECCCCCCC
VLRTHTSPVQMRTMLSRDLPIYIACPGRVFRTDELDATHTPVFHQVEGLAVDKGLTMAHL
EEEECCCHHHHHHHHHCCCCEEEECCCCEEECCCCCCCCCCHHHHHCCEEECCCCHHHHH
KGTLDHLAKTLFGEEAKTRIRPNYFPFTEPSAEVDVWFADKKGGAGWIEWGGCGMVNPNV
HHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCE
LIAAGVDPEEYSGFAFGMGIERTLQFRNGLPDMRDMVEGDVRFTLPFGVRR
EEEECCCHHHHCCEEECCCHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA