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The map label for this gene is infC [H]

Identifier: 68535909

GI number: 68535909

Start: 995655

End: 995999

Strand: Direct

Name: infC [H]

Synonym: jk0834

Alternate gene names: 68535909

Gene position: 995655-995999 (Clockwise)

Preceding gene: 68535907

Following gene: 68535910

Centisome position: 40.43

GC content: 59.13

Gene sequence:

>345_bases
ATGGACTACGGCAAGTTCAAGTACGAGCAGGCCCAGAAGGCCCGCGAAGCTCGTAAGAACCAGCAGCAGACCGTGGTGAA
GGAACAGAAGTTCCGTCCGAAGATCGACGACCACGACTACGAGACCAAGAAGGGCAACGTCATTCGTTTCCTGGAGAAGG
GCTCCAAGGTCAAGGTCACGATCATGTTCCGCGGGCGTGAGCAGTCTCGCCCGGAGCTCGGGTTCCGGTTGCTTGAGCGA
CTGGCAAACGACGTCGAGGAATACGGCGTAGTTGAGACCCGCGCCAAGCAAGACGGTCGCAACATGACCATGGTGCTGGG
CCCGGTCCGCAAGGGCAAGAAGTAG

Upstream 100 bases:

>100_bases
CGGTATCGTCAAGACAGACGATGCGCGAAAGCTGGCCTATGAAGCTGACCTCGACCTTGTAGAGGTTGCACCGAACGCCA
AGCCGCCCGTGGCAAAGATC

Downstream 100 bases:

>100_bases
TAACAGAACTAGTTGTTAGAGGTTTTTCACCAATGAAGCAGAAGACTCACAAGGGTGCCGCAAAGCGCATCAAGATCTCC
GGTTCCGGCAAGCTGCGTCG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MDYGKFKYEQAQKAREARKNQQQTVVKEQKFRPKIDDHDYETKKGNVIRFLEKGSKVKVTIMFRGREQSRPELGFRLLER
LANDVEEYGVVETRAKQDGRNMTMVLGPVRKGKK

Sequences:

>Translated_114_residues
MDYGKFKYEQAQKAREARKNQQQTVVKEQKFRPKIDDHDYETKKGNVIRFLEKGSKVKVTIMFRGREQSRPELGFRLLER
LANDVEEYGVVETRAKQDGRNMTMVLGPVRKGKK
>Mature_114_residues
MDYGKFKYEQAQKAREARKNQQQTVVKEQKFRPKIDDHDYETKKGNVIRFLEKGSKVKVTIMFRGREQSRPELGFRLLER
LANDVEEYGVVETRAKQDGRNMTMVLGPVRKGKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=112, Percent_Identity=47.3214285714286, Blast_Score=93, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 13436; Mature: 13436

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYGKFKYEQAQKAREARKNQQQTVVKEQKFRPKIDDHDYETKKGNVIRFLEKGSKVKVT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEE
IMFRGREQSRPELGFRLLERLANDVEEYGVVETRAKQDGRNMTMVLGPVRKGKK
EEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MDYGKFKYEQAQKAREARKNQQQTVVKEQKFRPKIDDHDYETKKGNVIRFLEKGSKVKVT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEE
IMFRGREQSRPELGFRLLERLANDVEEYGVVETRAKQDGRNMTMVLGPVRKGKK
EEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]