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The map label for this gene is ftsZ [H]

Identifier: 68535828

GI number: 68535828

Start: 900271

End: 901599

Strand: Direct

Name: ftsZ [H]

Synonym: jk0753

Alternate gene names: 68535828

Gene position: 900271-901599 (Clockwise)

Preceding gene: 68535827

Following gene: 68535829

Centisome position: 36.56

GC content: 64.26

Gene sequence:

>1329_bases
ATGACGAATCCTGGAAACCACCTCGCAGAGATCAAGGTGGTCGGTGTCGGCGGCGGCGGAGTAAACGCCGTCAATCGCAT
GATCGACGAGCAGCTGCAGGGTGTGGAGTTCATCGCCATTAACACCGATGCACAGGCTCTGATGCTGACCGATGCGGACA
TCAAGCTGGACATTGGCCGCGAGGAGACCCGCGGTCTGGGTGCTGGCGCTAACCCGGAGGTCGGGCGCAAGTCTGCCGAG
GATCACAAGGACCAGATTGAAGAGATCCTGGCCGGCGCCGACATGGTGTTCGTTACTGCAGGTGAGGGAGGCGGCACCGG
TACGGGTGCTGCCCCGGTCGTGGCAAACATCGCGAAGAAGCAGAATGCTCTGACCGTTGGTGTGGTTACCCGCCCCTTCG
GCTTCGAGGGCCGTCGCCGCAGCAAGCAGGCTATGGAGGGCATCGAAGCTCTGCGCGAGGTTTGCGACACGCTGATCGTT
ATCCCGAACGATTCGCTGCTGAAGATGTCCGAGGAGCAGCTGTCCATGATGGAGGCCTTCCGCAAGGCCGACGAGGTTCT
GCTCAGCGGTGTTGAGGGCATCACCAAGCTGATCACCACCCCGGGTGTGATCAACGTGGACTTCGCCGACGTGCGCTCTG
TTATGACCGACGCGGGCTCCGCCCTCATGGGTATCGGCACCGCCCGCGGCGACCAGCGCGCAATCAAGGCCACCCAAGCA
GCCATTAACTCTCCGCTGCTGGAGAGCACCATGGAAGGTGCCAAGGGCGTGCTGCTTTCCTTTGCCGGTGGCTCCGACCT
GGGCCTGTTGGAGGTTTCCCAGGCTGCCGACCTGGTGGAGGAGAAGGCCGACGAAGACGTCAACCTGATCTTCGGCACCA
TCATCGACGACCAGCTGGGCGACGAGGTCCGCGTGACCGTCATCGCCACTGGCTTCGACGACTCGCCATCCGCGCCGTCC
AACAACCAGCGTTCCGGCGCGCACCGTGCGCCGGAAGGTGCGGACGCAGGTGCTGCCCAGCCGACCAACCTGTTCGGTGG
CCAGGAAGCCCCGCAGGCTGGCCAGAGTTCTCAGTACGCAGTGCAGGGCCAGGAAGCCCCGCAGGTGGGCTCCGCGCAGG
CCAACCCGGCCGCACAGCAAGCCGGCACCCAGTCCAGCTTTGCGCAGCGCCGTGGAACCGTGCCGCAGCACGCACAGCAG
GAACAGCCGCAGGCTAACCAGGGCGGCGGCCTGTTTACCTCCGCTCCGCAGCAGCCGCAGAACCCCACCAACTCCGGTGT
GGATCTGACGGAGGAAGAAGACGATCTGGATCTGCCGGACTTCGACTAG

Upstream 100 bases:

>100_bases
ATGTGCATCGCTAAATGCTTGACGGCTAGGAAAATGGACGCAACAGCAAACCGGTAAACCGCAAAGCACGAAAATTCTTT
AGGAAGGCGGAAAGACGCAC

Downstream 100 bases:

>100_bases
TCGGTCGGGCACACAGCCCGCCCGCCACTAGCTTTCCAGTGACCAGCCTAAGGAGTTAGCTTTGAGCCAAGACCAGAGCC
CGAAGGTGCGAAAGGTCTTC

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTNPGNHLAEIKVVGVGGGGVNAVNRMIDEQLQGVEFIAINTDAQALMLTDADIKLDIGREETRGLGAGANPEVGRKSAE
DHKDQIEEILAGADMVFVTAGEGGGTGTGAAPVVANIAKKQNALTVGVVTRPFGFEGRRRSKQAMEGIEALREVCDTLIV
IPNDSLLKMSEEQLSMMEAFRKADEVLLSGVEGITKLITTPGVINVDFADVRSVMTDAGSALMGIGTARGDQRAIKATQA
AINSPLLESTMEGAKGVLLSFAGGSDLGLLEVSQAADLVEEKADEDVNLIFGTIIDDQLGDEVRVTVIATGFDDSPSAPS
NNQRSGAHRAPEGADAGAAQPTNLFGGQEAPQAGQSSQYAVQGQEAPQVGSAQANPAAQQAGTQSSFAQRRGTVPQHAQQ
EQPQANQGGGLFTSAPQQPQNPTNSGVDLTEEEDDLDLPDFD

Sequences:

>Translated_442_residues
MTNPGNHLAEIKVVGVGGGGVNAVNRMIDEQLQGVEFIAINTDAQALMLTDADIKLDIGREETRGLGAGANPEVGRKSAE
DHKDQIEEILAGADMVFVTAGEGGGTGTGAAPVVANIAKKQNALTVGVVTRPFGFEGRRRSKQAMEGIEALREVCDTLIV
IPNDSLLKMSEEQLSMMEAFRKADEVLLSGVEGITKLITTPGVINVDFADVRSVMTDAGSALMGIGTARGDQRAIKATQA
AINSPLLESTMEGAKGVLLSFAGGSDLGLLEVSQAADLVEEKADEDVNLIFGTIIDDQLGDEVRVTVIATGFDDSPSAPS
NNQRSGAHRAPEGADAGAAQPTNLFGGQEAPQAGQSSQYAVQGQEAPQVGSAQANPAAQQAGTQSSFAQRRGTVPQHAQQ
EQPQANQGGGLFTSAPQQPQNPTNSGVDLTEEEDDLDLPDFD
>Mature_441_residues
TNPGNHLAEIKVVGVGGGGVNAVNRMIDEQLQGVEFIAINTDAQALMLTDADIKLDIGREETRGLGAGANPEVGRKSAED
HKDQIEEILAGADMVFVTAGEGGGTGTGAAPVVANIAKKQNALTVGVVTRPFGFEGRRRSKQAMEGIEALREVCDTLIVI
PNDSLLKMSEEQLSMMEAFRKADEVLLSGVEGITKLITTPGVINVDFADVRSVMTDAGSALMGIGTARGDQRAIKATQAA
INSPLLESTMEGAKGVLLSFAGGSDLGLLEVSQAADLVEEKADEDVNLIFGTIIDDQLGDEVRVTVIATGFDDSPSAPSN
NQRSGAHRAPEGADAGAAQPTNLFGGQEAPQAGQSSQYAVQGQEAPQVGSAQANPAAQQAGTQSSFAQRRGTVPQHAQQE
QPQANQGGGLFTSAPQQPQNPTNSGVDLTEEEDDLDLPDFD

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=292, Percent_Identity=51.027397260274, Blast_Score=255, Evalue=4e-69,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 45939; Mature: 45808

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPGNHLAEIKVVGVGGGGVNAVNRMIDEQLQGVEFIAINTDAQALMLTDADIKLDIGR
CCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCCEEEECCC
EETRGLGAGANPEVGRKSAEDHKDQIEEILAGADMVFVTAGEGGGTGTGAAPVVANIAKK
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
QNALTVGVVTRPFGFEGRRRSKQAMEGIEALREVCDTLIVIPNDSLLKMSEEQLSMMEAF
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHH
RKADEVLLSGVEGITKLITTPGVINVDFADVRSVMTDAGSALMGIGTARGDQRAIKATQA
HHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHH
AINSPLLESTMEGAKGVLLSFAGGSDLGLLEVSQAADLVEEKADEDVNLIFGTIIDDQLG
HHCCHHHHHHHHCCCEEEEEECCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEHHHHCCC
DEVRVTVIATGFDDSPSAPSNNQRSGAHRAPEGADAGAAQPTNLFGGQEAPQAGQSSQYA
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VQGQEAPQVGSAQANPAAQQAGTQSSFAQRRGTVPQHAQQEQPQANQGGGLFTSAPQQPQ
ECCCCCCCCCCCCCCCHHHHCCCHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC
NPTNSGVDLTEEEDDLDLPDFD
CCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TNPGNHLAEIKVVGVGGGGVNAVNRMIDEQLQGVEFIAINTDAQALMLTDADIKLDIGR
CCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCCEEEECCC
EETRGLGAGANPEVGRKSAEDHKDQIEEILAGADMVFVTAGEGGGTGTGAAPVVANIAKK
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
QNALTVGVVTRPFGFEGRRRSKQAMEGIEALREVCDTLIVIPNDSLLKMSEEQLSMMEAF
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHH
RKADEVLLSGVEGITKLITTPGVINVDFADVRSVMTDAGSALMGIGTARGDQRAIKATQA
HHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHH
AINSPLLESTMEGAKGVLLSFAGGSDLGLLEVSQAADLVEEKADEDVNLIFGTIIDDQLG
HHCCHHHHHHHHCCCEEEEEECCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEHHHHCCC
DEVRVTVIATGFDDSPSAPSNNQRSGAHRAPEGADAGAAQPTNLFGGQEAPQAGQSSQYA
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VQGQEAPQVGSAQANPAAQQAGTQSSFAQRRGTVPQHAQQEQPQANQGGGLFTSAPQQPQ
ECCCCCCCCCCCCCCCHHHHCCCHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC
NPTNSGVDLTEEEDDLDLPDFD
CCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9240446; 9738885; 12948626 [H]