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The map label for this gene is yfbQ [H]

Identifier: 66767133

GI number: 66767133

Start: 954779

End: 956050

Strand: Reverse

Name: yfbQ [H]

Synonym: XC_0800

Alternate gene names: 66767133

Gene position: 956050-954779 (Counterclockwise)

Preceding gene: 66767138

Following gene: 66767132

Centisome position: 18.57

GC content: 66.98

Gene sequence:

>1272_bases
ATGTCCACCGCCCCGCAAAAGCCGCTCGCCATCCGCGAGCGCCTGTCCGAAGTCCGCTACGAGATCCGGGGCGAACTGGC
GCGGCGAGCGCGGGAGTTGGAGGCGCAGGGCCGCAAGCTGATCAAGCTCAACATCGGCAACCCCGGTGCATTCGGGTTCC
GTGCGCCGGAGCATCTGCAGCGTGCGATTGCCGACGACATGGGCCGCACCGATCCCTATACGCATCAGCAGGGCCTGCCG
GAAGCACGCGAGGCGATCGCGGCCGCGTATGCGCGCCGCCAGCATCCGGATGCACATCCGGACCGGATCTTTATCGGCAA
CGGCGTCAGCGAACTGATCGACCTGTCACTGCGCGCCCTGCTGAACCCCGGCGACGAAGTGCTGGTGCCCTCGCCCGATT
ACCCGCTGTGGTCGGCGGCCACCATCCTCAACGACGGCCGCCCGGTGTATTACCGCTGCGCGCCGGAGAATGGCTTCCAG
CCGGACCCGGTGGAAATCGAGACACTGGTGTCGTCGCGCACGCGCGCCATCGTGCTGATCAATCCGAACAACCCCAGCGG
CGCCAGTTATTCGCGCGAGTTGCTGGAGCGCATCGTCGCCATCGCGGTCAAGCACAACCTGCTGTTGATGGTGGACGAGA
TCTACGACCAGGTGCTGTATGACGGTGCGGCGTTTGTGCCGGTGGCACCGCTGGCTGGCGAGCACCCGTGCATCACCTTC
AGCGGGCTGAGCAAGGTGCACCGCGCCTGCGGCTGGCGGGTGGGTTGGGCGCTGTTGTCCGGTGAGCAATCGCGCATCAA
CGATCTGCGCAACGCCATGGACCTGCTCGGCGCGCTGCGCCTGTGCGCGAATGTGCCGGGCCAGTATGCAATCGACGCGG
CAGTCAACGGGCCGGACACCATCTCGGCGCTGTGCGCGCCGGGTGGACGCCTGTACGAGACCCGCCGCGCGGTGATCGAA
GCATGCGCGGCCAGCTCACATCTGTCGTTGGTTGCACCGGCCGGCGCGCTGTATGCGTTCCCGGCAGTGGTGGGGCCGGC
GGCGCGTGCTTTCGACGACCACACCTTCGCGCTGGATCTGATGAACGACGAAGGCGTGCTGGTGGTGCCGGGCTCCAGCT
TCAACGTGCCGTATCGCCACCATTTCCGCGTGACGCTGATGCCCGAAGCTGCGGTGATGCGCGATGTGTTTGCGCGCATC
GATCGCGCCCTGACGCGACGTGCAGAGGCGGTGACCAAGGTCGTGCCGCTCAAGTCGCGCAGCGTGGCGTGA

Upstream 100 bases:

>100_bases
CGGCCGGTGACCGGCCTTGACATTGTTGCCAATGCAAGCATGTCCGCCTGTCATATTTCCGCTACCATGCCAAGCCTCAC
GCCTACAACCGGCCTGCCGT

Downstream 100 bases:

>100_bases
TGGCGGCGGTCGGCCTGCCGCGGCGCTATCTGGCGCTGGGCGACTCCTACACCATCGGCGAGGGCGTCGCCGCCGAGCAG
CGCTGGCCGGAGCAACTGGC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSTAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLP
EAREAIAAAYARRQHPDAHPDRIFIGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQ
PDPVEIETLVSSRTRAIVLINPNNPSGASYSRELLERIVAIAVKHNLLLMVDEIYDQVLYDGAAFVPVAPLAGEHPCITF
SGLSKVHRACGWRVGWALLSGEQSRINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTISALCAPGGRLYETRRAVIE
ACAASSHLSLVAPAGALYAFPAVVGPAARAFDDHTFALDLMNDEGVLVVPGSSFNVPYRHHFRVTLMPEAAVMRDVFARI
DRALTRRAEAVTKVVPLKSRSVA

Sequences:

>Translated_423_residues
MSTAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLP
EAREAIAAAYARRQHPDAHPDRIFIGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQ
PDPVEIETLVSSRTRAIVLINPNNPSGASYSRELLERIVAIAVKHNLLLMVDEIYDQVLYDGAAFVPVAPLAGEHPCITF
SGLSKVHRACGWRVGWALLSGEQSRINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTISALCAPGGRLYETRRAVIE
ACAASSHLSLVAPAGALYAFPAVVGPAARAFDDHTFALDLMNDEGVLVVPGSSFNVPYRHHFRVTLMPEAAVMRDVFARI
DRALTRRAEAVTKVVPLKSRSVA
>Mature_422_residues
STAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLPE
AREAIAAAYARRQHPDAHPDRIFIGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQP
DPVEIETLVSSRTRAIVLINPNNPSGASYSRELLERIVAIAVKHNLLLMVDEIYDQVLYDGAAFVPVAPLAGEHPCITFS
GLSKVHRACGWRVGWALLSGEQSRINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTISALCAPGGRLYETRRAVIEA
CAASSHLSLVAPAGALYAFPAVVGPAARAFDDHTFALDLMNDEGVLVVPGSSFNVPYRHHFRVTLMPEAAVMRDVFARID
RALTRRAEAVTKVVPLKSRSVA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=381, Percent_Identity=27.8215223097113, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=28.3482142857143, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI19263340, Length=479, Percent_Identity=25.4697286012526, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI215599424, Length=397, Percent_Identity=27.7078085642317, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI95147551, Length=216, Percent_Identity=31.0185185185185, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI169881279, Length=216, Percent_Identity=31.0185185185185, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI169881281, Length=143, Percent_Identity=34.2657342657343, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI56713254, Length=214, Percent_Identity=28.0373831775701, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI56713256, Length=214, Percent_Identity=28.0373831775701, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788627, Length=398, Percent_Identity=43.4673366834171, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI1788722, Length=392, Percent_Identity=25, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=26.4248704663212, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=27.8820375335121, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71981209, Length=463, Percent_Identity=27.645788336933, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=23.9010989010989, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=23.0769230769231, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=296, Percent_Identity=27.3648648648649, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567369, Length=272, Percent_Identity=24.6323529411765, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=457, Percent_Identity=26.2582056892779, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6320317, Length=461, Percent_Identity=25.1626898047722, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=239, Percent_Identity=29.2887029288703, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322075, Length=188, Percent_Identity=30.8510638297872, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859735, Length=383, Percent_Identity=28.1984334203655, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI45551451, Length=455, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24641770, Length=455, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641760, Length=455, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641768, Length=455, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641766, Length=455, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641764, Length=455, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573069, Length=403, Percent_Identity=25.3101736972705, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646114, Length=403, Percent_Identity=25.3101736972705, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28573067, Length=403, Percent_Identity=25.3101736972705, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28573065, Length=403, Percent_Identity=25.3101736972705, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 46139; Mature: 46008

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHH
RAIADDMGRTDPYTHQQGLPEAREAIAAAYARRQHPDAHPDRIFIGNGVSELIDLSLRAL
HHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHH
LNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQPDPVEIETLVSSRTRAIVLI
CCCCCCEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEE
NPNNPSGASYSRELLERIVAIAVKHNLLLMVDEIYDQVLYDGAAFVPVAPLAGEHPCITF
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCEEEECCCCCCCCEEEH
SGLSKVHRACGWRVGWALLSGEQSRINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDT
HHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHH
ISALCAPGGRLYETRRAVIEACAASSHLSLVAPAGALYAFPAVVGPAARAFDDHTFALDL
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCHHHHHCCCCEEEEEE
MNDEGVLVVPGSSFNVPYRHHFRVTLMPEAAVMRDVFARIDRALTRRAEAVTKVVPLKSR
ECCCCEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVA
CCC
>Mature Secondary Structure 
STAPQKPLAIRERLSEVRYEIRGELARRARELEAQGRKLIKLNIGNPGAFGFRAPEHLQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHH
RAIADDMGRTDPYTHQQGLPEAREAIAAAYARRQHPDAHPDRIFIGNGVSELIDLSLRAL
HHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHH
LNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQPDPVEIETLVSSRTRAIVLI
CCCCCCEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEE
NPNNPSGASYSRELLERIVAIAVKHNLLLMVDEIYDQVLYDGAAFVPVAPLAGEHPCITF
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCEEEECCCCCCCCEEEH
SGLSKVHRACGWRVGWALLSGEQSRINDLRNAMDLLGALRLCANVPGQYAIDAAVNGPDT
HHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHH
ISALCAPGGRLYETRRAVIEACAASSHLSLVAPAGALYAFPAVVGPAARAFDDHTFALDL
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCHHHHHCCCCEEEEEE
MNDEGVLVVPGSSFNVPYRHHFRVTLMPEAAVMRDVFARIDRALTRRAEAVTKVVPLKSR
ECCCCEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]