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The map label for this gene is tcp [H]

Identifier: 66766976

GI number: 66766976

Start: 763954

End: 765906

Strand: Reverse

Name: tcp [H]

Synonym: XC_0638

Alternate gene names: 66766976

Gene position: 765906-763954 (Counterclockwise)

Preceding gene: 66766977

Following gene: 66766974

Centisome position: 14.88

GC content: 64.06

Gene sequence:

>1953_bases
ATGCAGCACTACGCCGACAAGGTGAAGGCCGGCGAGCTGAGCAAGCAACAAGCCATGGAAGCGGCGCGTACCACGCTGGC
GGATATGCGCACCAATGACGGCGTGGATTACTTCTTCATCGTCGACCCGCAGATGCGCATCCTGATGCATCCCAAGCGGC
CGGTCGGCACGGACATGTCCGATTACAAGAGTGACGCCGGGCAGTACGTCTACCGCGATATCAAGACCGCCATCGACAGC
GGCGATGGCTTCAGCTACTACGACGCGCCCAAGCCCGGCAAGAGAGAGCAGTTGCCCAAGATCAGCTATGCCAAGGTGTT
TCCGGCCTGGAACTGGGTGCTGGTGATGGGCGTGTACGCCGAAGACATCCAGGTGCAGGCGTGGGGATTCACCCGCACGC
TGACGCTGATCGGCGGCGCGCTGGTAGCCATGGTGATCGGCCTGTGCTGGTTGATTGCCTCGGCCATGGCTGCACCGCTG
CGTGCTGCAACGCGCACCGCCGAGGCGATCGCTTCGGGCCGGTTCGACAACGACATCCGCGTCGAGTCGCGCGATGAAAC
CGGCCAGCTGATGCACAGCATGGCGCAGATGCAAACCCAGCTGCAGCGCTTCAATGGCGAGATGCAGACCATGATCCGCC
TGCAGCAGGGGGAAAACATCGCGCACCGCATCCCGGAAGACTTCCCCGGCGATTACGGCAGCCTGGCGCATGGCGTGAAC
ACAGTGGTCTTCGAGCACCTGGACGCCATCAACGAAGCGATGGATGTGATGAGCGACTATGGCCGCGGCGATCTGCGCCG
CGACATGCGCCGCCTGCCCGGCCAGCGCGCAGCGCTGCATGAGGCGCTGGACACGGTGAAGACCAATCTGTCGGCGATCA
ATGGCGATATCGCGCGGCTTGCCGATGCCGCCGCGCGCGGCGATTTCTCCGCACGTGGCGACCAGGCGCGCTATCAGTTC
GCCTTCGCGGAAATGGTGCAGGCGCTCAACCGTTTGATGCAGCAGGCCGACGCCGGCCTGGACGATGTCGGCCGCATCAT
GGCCGCGATCGCCGACGGCGATTTGTCGCAGCGGGTGGAATCGCATTACGAAGGTGCGTTCGGGCGCCTGGCCAATGCGG
CCAACCGCACCGCGATCCAGCTCACTACTATCGTGCAAGGCATCCAGCAGTCGGCAGAGATGATCAACACTGCGGCCGGT
GAGATCGCCAGCGGCAATTCCGACCTGTCCACGCGCACCGAGCATCAGGCTGCCAACCTCGAAGAAACCGCTGCCTCCAT
GGAGGAACTCACCTCCACCGTGCGCCAGAACGCCGACAACGCGCGCCAGGCCAATCAACTGGTCAAGGGCACCGGTGACG
TAGCCGAAAGCGGCGGCCGCGTGGTGCAGGAAGTGGTCAGCACCATGCTGGCGATCACGCAATCGTCCGCACGCATTTCC
GACATCATCGGGGTGATCGACGGCATCGCTTTCCAGACCAATATCCTTGCGTTGAACGCCGCGGTGGAAGCCGCACGTGC
CGGCGAACAGGGCCGCGGGTTTGCGGTGGTGGCCAGCGAAGTACGTGCGTTGGCGCAGCGTTCGGCTGGCGCGGCAAAGG
AAATCAAGCAGCTGATTTCCGACTCGGTGGAAAAGGTCGAGCAAGGCTCGGGCCTGGTGGAACAGGCCGGCAGCACGATG
ACCGAGGTGGTGAGTTCGGTGAAGCGGGTGACCGACATCATGGCCGAGATCACCGCCGCCAGTACCGAACAGAGCGCTGG
CATCGAGCAGGTCAGCACCACGGTGATGCAACTGGATGAAATGACCCAGCAAAACGCAGCGCTGGTAGAAGAAGCCACCG
CCGCAGCGCGCAGCCTGGAAGATCAGGCCGCCGAGCTGACGCGCGCGGTGTCGGTGTTCCGCTTGGTGCCGGCACAGGCC
GAGCAGCGGCAGCGGCACGTACAGGCCGCCTGA

Upstream 100 bases:

>100_bases
GATCCTGCTGGCGGTTGCCGCAGCGCGTCTGCAATACCTGGATCTGGTCGAAGCACGCAAGCTCAGCGTCAAGACCGAAG
TGGAAATGGGCCTGACGGTG

Downstream 100 bases:

>100_bases
CGTTCTGTATTGGCAGGCACTGCGCACCGCGGATGTTGGTGTGCAGTGCACTAGCAGGCGCTTAGTGAGCTTCCGGGGCC
GAGGCGATAGCAGACTTGTA

Product: chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MQHYADKVKAGELSKQQAMEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVGTDMSDYKSDAGQYVYRDIKTAIDS
GDGFSYYDAPKPGKREQLPKISYAKVFPAWNWVLVMGVYAEDIQVQAWGFTRTLTLIGGALVAMVIGLCWLIASAMAAPL
RAATRTAEAIASGRFDNDIRVESRDETGQLMHSMAQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGSLAHGVN
TVVFEHLDAINEAMDVMSDYGRGDLRRDMRRLPGQRAALHEALDTVKTNLSAINGDIARLADAAARGDFSARGDQARYQF
AFAEMVQALNRLMQQADAGLDDVGRIMAAIADGDLSQRVESHYEGAFGRLANAANRTAIQLTTIVQGIQQSAEMINTAAG
EIASGNSDLSTRTEHQAANLEETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMLAITQSSARIS
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRALAQRSAGAAKEIKQLISDSVEKVEQGSGLVEQAGSTM
TEVVSSVKRVTDIMAEITAASTEQSAGIEQVSTTVMQLDEMTQQNAALVEEATAAARSLEDQAAELTRAVSVFRLVPAQA
EQRQRHVQAA

Sequences:

>Translated_650_residues
MQHYADKVKAGELSKQQAMEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVGTDMSDYKSDAGQYVYRDIKTAIDS
GDGFSYYDAPKPGKREQLPKISYAKVFPAWNWVLVMGVYAEDIQVQAWGFTRTLTLIGGALVAMVIGLCWLIASAMAAPL
RAATRTAEAIASGRFDNDIRVESRDETGQLMHSMAQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGSLAHGVN
TVVFEHLDAINEAMDVMSDYGRGDLRRDMRRLPGQRAALHEALDTVKTNLSAINGDIARLADAAARGDFSARGDQARYQF
AFAEMVQALNRLMQQADAGLDDVGRIMAAIADGDLSQRVESHYEGAFGRLANAANRTAIQLTTIVQGIQQSAEMINTAAG
EIASGNSDLSTRTEHQAANLEETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMLAITQSSARIS
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRALAQRSAGAAKEIKQLISDSVEKVEQGSGLVEQAGSTM
TEVVSSVKRVTDIMAEITAASTEQSAGIEQVSTTVMQLDEMTQQNAALVEEATAAARSLEDQAAELTRAVSVFRLVPAQA
EQRQRHVQAA
>Mature_650_residues
MQHYADKVKAGELSKQQAMEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVGTDMSDYKSDAGQYVYRDIKTAIDS
GDGFSYYDAPKPGKREQLPKISYAKVFPAWNWVLVMGVYAEDIQVQAWGFTRTLTLIGGALVAMVIGLCWLIASAMAAPL
RAATRTAEAIASGRFDNDIRVESRDETGQLMHSMAQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGSLAHGVN
TVVFEHLDAINEAMDVMSDYGRGDLRRDMRRLPGQRAALHEALDTVKTNLSAINGDIARLADAAARGDFSARGDQARYQF
AFAEMVQALNRLMQQADAGLDDVGRIMAAIADGDLSQRVESHYEGAFGRLANAANRTAIQLTTIVQGIQQSAEMINTAAG
EIASGNSDLSTRTEHQAANLEETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMLAITQSSARIS
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRALAQRSAGAAKEIKQLISDSVEKVEQGSGLVEQAGSTM
TEVVSSVKRVTDIMAEITAASTEQSAGIEQVSTTVMQLDEMTQQNAALVEEATAAARSLEDQAAELTRAVSVFRLVPAQA
EQRQRHVQAA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=299, Percent_Identity=58.5284280936455, Blast_Score=291, Evalue=9e-80,
Organism=Escherichia coli, GI2367378, Length=327, Percent_Identity=57.1865443425077, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1787690, Length=286, Percent_Identity=58.3916083916084, Blast_Score=285, Evalue=9e-78,
Organism=Escherichia coli, GI1788194, Length=251, Percent_Identity=60.5577689243028, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1789453, Length=233, Percent_Identity=44.206008583691, Blast_Score=183, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 70275; Mature: 70275

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHYADKVKAGELSKQQAMEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVGTDMS
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCCCCHH
DYKSDAGQYVYRDIKTAIDSGDGFSYYDAPKPGKREQLPKISYAKVFPAWNWVLVMGVYA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHHCCCCCHHHEEEEHH
EDIQVQAWGFTRTLTLIGGALVAMVIGLCWLIASAMAAPLRAATRTAEAIASGRFDNDIR
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VESRDETGQLMHSMAQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGSLAHGVN
ECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHH
TVVFEHLDAINEAMDVMSDYGRGDLRRDMRRLPGQRAALHEALDTVKTNLSAINGDIARL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
ADAAARGDFSARGDQARYQFAFAEMVQALNRLMQQADAGLDDVGRIMAAIADGDLSQRVE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHH
SHYEGAFGRLANAANRTAIQLTTIVQGIQQSAEMINTAAGEIASGNSDLSTRTEHQAANL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCH
EETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMLAITQSSARIS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRALAQRSAGAAKEIKQLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
DSVEKVEQGSGLVEQAGSTMTEVVSSVKRVTDIMAEITAASTEQSAGIEQVSTTVMQLDE
HHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHH
MTQQNAALVEEATAAARSLEDQAAELTRAVSVFRLVPAQAEQRQRHVQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MQHYADKVKAGELSKQQAMEAARTTLADMRTNDGVDYFFIVDPQMRILMHPKRPVGTDMS
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCCCCHH
DYKSDAGQYVYRDIKTAIDSGDGFSYYDAPKPGKREQLPKISYAKVFPAWNWVLVMGVYA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHHCCCCCHHHEEEEHH
EDIQVQAWGFTRTLTLIGGALVAMVIGLCWLIASAMAAPLRAATRTAEAIASGRFDNDIR
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VESRDETGQLMHSMAQMQTQLQRFNGEMQTMIRLQQGENIAHRIPEDFPGDYGSLAHGVN
ECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHH
TVVFEHLDAINEAMDVMSDYGRGDLRRDMRRLPGQRAALHEALDTVKTNLSAINGDIARL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
ADAAARGDFSARGDQARYQFAFAEMVQALNRLMQQADAGLDDVGRIMAAIADGDLSQRVE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHH
SHYEGAFGRLANAANRTAIQLTTIVQGIQQSAEMINTAAGEIASGNSDLSTRTEHQAANL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCH
EETAASMEELTSTVRQNADNARQANQLVKGTGDVAESGGRVVQEVVSTMLAITQSSARIS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRALAQRSAGAAKEIKQLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
DSVEKVEQGSGLVEQAGSTMTEVVSSVKRVTDIMAEITAASTEQSAGIEQVSTTVMQLDE
HHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHH
MTQQNAALVEEATAAARSLEDQAAELTRAVSVFRLVPAQAEQRQRHVQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]