Click here to switch to the map view.

The map label for this gene is clp

Identifier: 66766825

GI number: 66766825

Start: 575713

End: 576405

Strand: Reverse

Name: clp

Synonym: XC_0486

Alternate gene names: 66766825

Gene position: 576405-575713 (Counterclockwise)

Preceding gene: 66766828

Following gene: 77761086

Centisome position: 11.2

GC content: 61.76

Gene sequence:

>693_bases
ATGAGCCTAGGGAACACGACGGTTGTGACTACGACGGTACGTAACGCTACCCCCTCACTGACGCTGGACGCGGGCACCAT
TGAGCGATTCCTGGCGCACAGCCACCGCAGGCGCTATCCGACCCGGACCGATGTGTTCCGGCCGGGAGACCCCGCTGGCA
CCCTCTACTACGTGATCAGCGGCTCGGTGAGCATCATTGCCGAGGAAGATGACGATCGTGAGTTGGTGCTGGGCTACTTC
GGTAGCGGCGAGTTCGTTGGTGAGATGGGGTTGTTCATCGAATCCGATACGCGCGAAGTGATCCTGCGCACCCGCACGCA
ATGCGAGTTGGCTGAAATCAGCTACGAGCGCCTGCAGCAGCTGTTTCAGACGAGTTTGTCGCCGGATGCGCCGCGAATCC
TGTACGCCATTGGCGTTCAGCTTTCAAAACGCCTGCTCGATACCACAAGGAAAGCCAGCCGCCTGGCGTTCCTGGATGTG
ACCGATCGCATCGTGCGCACGCTGCACGATCTGTCGAAGGAGCCGGAGGCGATGAGCCATCCGCAGGGTACGCAGTTGCG
CGTCTCGCGGCAGGAACTCGCGCGCCTGGTCGGCTGCTCGCGCGAAATGGCCGGACGCGTCCTGAAGAAATTGCAGGCCG
ATGGCCTGTTGCATGCACGCGGCAAGACCGTCGTGTTGTACGGCACGCGCTAA

Upstream 100 bases:

>100_bases
TTATGGGCCAAAGCTCTCATCAACGAAATGCCGGCGTTGAGAATGGTTTACCTTGCATGACTCATGCCGTTAAGCTTCGG
GAATTACACGCGGAACTACC

Downstream 100 bases:

>100_bases
GCGTGGGGTGGCGATCGGTGCGCTGGCGCACCGATCGCTTCGCGATACCGGTGGCGCCGGCGCAAAACCGGCCAAACGCT
GCGCCAGAGCGCTGCATATC

Product: cAMP-regulatory protein

Products: NA

Alternate protein names: CAP-like

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSLGNTTVVTTTVRNATPSLTLDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYF
GSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQTSLSPDAPRILYAIGVQLSKRLLDTTRKASRLAFLDV
TDRIVRTLHDLSKEPEAMSHPQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR

Sequences:

>Translated_230_residues
MSLGNTTVVTTTVRNATPSLTLDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYF
GSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQTSLSPDAPRILYAIGVQLSKRLLDTTRKASRLAFLDV
TDRIVRTLHDLSKEPEAMSHPQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR
>Mature_229_residues
SLGNTTVVTTTVRNATPSLTLDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYFG
SGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQTSLSPDAPRILYAIGVQLSKRLLDTTRKASRLAFLDVT
DRIVRTLHDLSKEPEAMSHPQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR

Specific function: Involved in the regulation of phytopathogenicity. It controls the production of extracellular enzymes, xanthan gum, and pigment either positively or negatively

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789756, Length=205, Percent_Identity=45.3658536585366, Blast_Score=214, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLP_XANCP (P22260)

Other databases:

- EMBL:   M58745
- EMBL:   M92289
- EMBL:   AE008922
- PIR:   A42949
- RefSeq:   NP_635866.1
- PDB:   3IWZ
- PDBsum:   3IWZ
- ProteinModelPortal:   P22260
- SMR:   P22260
- GeneID:   1000958
- GenomeReviews:   AE008922_GR
- KEGG:   xcc:XCC0472
- HOGENOM:   HBG648099
- OMA:   RAKSACE
- ProtClustDB:   PRK11753
- BioCyc:   XCAM190485:XCC0472-MONOMER
- GO:   GO:0005622
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991
- Gene3D:   G3DSA:2.60.120.10
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00034
- SMART:   SM00100
- SMART:   SM00419

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp; SSF51206 cNMP_binding

EC number: NA

Molecular weight: Translated: 25712; Mature: 25581

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50042 CNMP_BINDING_3; PS00042 HTH_CRP_1; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGNTTVVTTTVRNATPSLTLDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVIS
CCCCCCEEEEEEECCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
GSVSIIAEEDDDRELVLGYFGSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQ
CCEEEEEECCCCCEEEEEECCCCCEEEEECEEEECCCHHHHHHHCCHHHHHHHHHHHHHH
LFQTSLSPDAPRILYAIGVQLSKRLLDTTRKASRLAFLDVTDRIVRTLHDLSKEPEAMSH
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHCCCCCHHCC
PQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR
CCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCEEEEEECC
>Mature Secondary Structure 
SLGNTTVVTTTVRNATPSLTLDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVIS
CCCCCEEEEEEECCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
GSVSIIAEEDDDRELVLGYFGSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQ
CCEEEEEECCCCCEEEEEECCCCCEEEEECEEEECCCHHHHHHHCCHHHHHHHHHHHHHH
LFQTSLSPDAPRILYAIGVQLSKRLLDTTRKASRLAFLDVTDRIVRTLHDLSKEPEAMSH
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHCCCCCHHCC
PQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR
CCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2170330; 1322886; 12024217