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The map label for this gene is yafC [C]

Identifier: 66766390

GI number: 66766390

Start: 50747

End: 51649

Strand: Reverse

Name: yafC [C]

Synonym: XC_0040

Alternate gene names: 66766390

Gene position: 51649-50747 (Counterclockwise)

Preceding gene: 66766391

Following gene: 66766388

Centisome position: 1.0

GC content: 67.77

Gene sequence:

>903_bases
GTGCCTGCCGTGATCGACCTCAATGACATTGCGCTGTATGTGCAGGTCGTGCGTAGCGGCAGTTTTGCCGAGGCCGCGCG
CCGGCTGGGCACCGCGCCCAATAGCGTGAGCCGGCGCGTGCAGCAGCTCGAAGCGCAGCTGGATACGCGGCTGATGCAGC
GCTCCACCCGCAAGCTCACCCTGACCGATGCCGGGCAGGCGTTTTACGAACGTTGCGGCGATGCGGTGGACGGGCTGACC
GATGCCGGGCAATCGCTGGTGGCCGGTGGCGAGGAGGTCGCTGGCCTGGTGCGGGTGGCAGCGCCGGCGGATTTCCTGGA
TTTCTTCCGGGTCGAATGGGTGGCCGACTTCCTGGCCGCGCATCCGCGCGTGCGCCTGGAATTCTTGCTCAGCGATGCGC
GCGCGGATCTGATTGCCGAGCGCATCGACGTGGCATTTCGCGCCGGCATCCTGGCCGACTCCAGTTACGTGGGGCGGCCG
ATCCTGGCCGACAACCGCGATGTGCTGGTGGCGAGCCCAGGTTATCTGCAGGCACGTGGCAGGCCGCTGCGCCTGGATGA
GCTGCCGCAGCACGATTGCCTGGGCATTCCGCATCCCAGCGGGCACGTCAGCTGGACGCTGGTAGGTCCGTCCGGGCTTG
CCGAGACAGTGCAGGTGCCCACCCGTTTTGCCGCAAATACAGCGCGCGCGCTACGCTTGGCGGCCGTGGCCGGGCTGGGA
ATCGCCTTGTTGCCGCAGGCACTGACCTGGCCGGATGTGGCCGAAGGCCGCCTGGTCACGGTGTTGCCGGATTTCCAGCG
CAATGGCCAGGGCGTGCATGCGCTGTATCCCAGCCGGCGGCATCAGCCGCGCGCGGTGACGGCGTTTATCGAGGCGGTCA
GCGCGCGCTTGAATGCGATGTAG

Upstream 100 bases:

>100_bases
GCATCCATGCAGGGACGCGTCGGGCCTGATCAGCGCCTGCCGTCCGACGCACAACACCTGATCCCCGGCGCGCTTAAACT
CACCGCAGACCGACAAAGGT

Downstream 100 bases:

>100_bases
CGCGGTGCGCGGGCATTGGTTGAGTAGATGATCGATGATTTCCTGCGCGCGTTTTGCGACTAAGTGCAGCTAACAAAACG
TAGCGCGCAACCGTCAGACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPAVIDLNDIALYVQVVRSGSFAEAARRLGTAPNSVSRRVQQLEAQLDTRLMQRSTRKLTLTDAGQAFYERCGDAVDGLT
DAGQSLVAGGEEVAGLVRVAAPADFLDFFRVEWVADFLAAHPRVRLEFLLSDARADLIAERIDVAFRAGILADSSYVGRP
ILADNRDVLVASPGYLQARGRPLRLDELPQHDCLGIPHPSGHVSWTLVGPSGLAETVQVPTRFAANTARALRLAAVAGLG
IALLPQALTWPDVAEGRLVTVLPDFQRNGQGVHALYPSRRHQPRAVTAFIEAVSARLNAM

Sequences:

>Translated_300_residues
MPAVIDLNDIALYVQVVRSGSFAEAARRLGTAPNSVSRRVQQLEAQLDTRLMQRSTRKLTLTDAGQAFYERCGDAVDGLT
DAGQSLVAGGEEVAGLVRVAAPADFLDFFRVEWVADFLAAHPRVRLEFLLSDARADLIAERIDVAFRAGILADSSYVGRP
ILADNRDVLVASPGYLQARGRPLRLDELPQHDCLGIPHPSGHVSWTLVGPSGLAETVQVPTRFAANTARALRLAAVAGLG
IALLPQALTWPDVAEGRLVTVLPDFQRNGQGVHALYPSRRHQPRAVTAFIEAVSARLNAM
>Mature_299_residues
PAVIDLNDIALYVQVVRSGSFAEAARRLGTAPNSVSRRVQQLEAQLDTRLMQRSTRKLTLTDAGQAFYERCGDAVDGLTD
AGQSLVAGGEEVAGLVRVAAPADFLDFFRVEWVADFLAAHPRVRLEFLLSDARADLIAERIDVAFRAGILADSSYVGRPI
LADNRDVLVASPGYLQARGRPLRLDELPQHDCLGIPHPSGHVSWTLVGPSGLAETVQVPTRFAANTARALRLAAVAGLGI
ALLPQALTWPDVAEGRLVTVLPDFQRNGQGVHALYPSRRHQPRAVTAFIEAVSARLNAM

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=31.5068493150685, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI145693193, Length=286, Percent_Identity=28.6713286713287, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=29.6928327645051, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=29.0657439446367, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=26.6211604095563, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87081978, Length=287, Percent_Identity=30.6620209059233, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=24.3150684931507, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789492, Length=264, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786448, Length=286, Percent_Identity=25.5244755244755, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=265, Percent_Identity=26.0377358490566, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788748, Length=155, Percent_Identity=31.6129032258064, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789173, Length=262, Percent_Identity=26.3358778625954, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32383; Mature: 32252

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAVIDLNDIALYVQVVRSGSFAEAARRLGTAPNSVSRRVQQLEAQLDTRLMQRSTRKLT
CCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTDAGQAFYERCGDAVDGLTDAGQSLVAGGEEVAGLVRVAAPADFLDFFRVEWVADFLAA
EECCHHHHHHHHCHHHHHHHHCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
HPRVRLEFLLSDARADLIAERIDVAFRAGILADSSYVGRPILADNRDVLVASPGYLQARG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCEEECCCCEEEECCCCCCCCC
RPLRLDELPQHDCLGIPHPSGHVSWTLVGPSGLAETVQVPTRFAANTARALRLAAVAGLG
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCH
IALLPQALTWPDVAEGRLVTVLPDFQRNGQGVHALYPSRRHQPRAVTAFIEAVSARLNAM
HHHHCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAVIDLNDIALYVQVVRSGSFAEAARRLGTAPNSVSRRVQQLEAQLDTRLMQRSTRKLT
CCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTDAGQAFYERCGDAVDGLTDAGQSLVAGGEEVAGLVRVAAPADFLDFFRVEWVADFLAA
EECCHHHHHHHHCHHHHHHHHCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
HPRVRLEFLLSDARADLIAERIDVAFRAGILADSSYVGRPILADNRDVLVASPGYLQARG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCEEECCCCEEEECCCCCCCCC
RPLRLDELPQHDCLGIPHPSGHVSWTLVGPSGLAETVQVPTRFAANTARALRLAAVAGLG
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCH
IALLPQALTWPDVAEGRLVTVLPDFQRNGQGVHALYPSRRHQPRAVTAFIEAVSARLNAM
HHHHCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]