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The map label for this gene is folE2 [H]

Identifier: 66045509

GI number: 66045509

Start: 2635090

End: 2635995

Strand: Direct

Name: folE2 [H]

Synonym: Psyr_2269

Alternate gene names: 66045509

Gene position: 2635090-2635995 (Clockwise)

Preceding gene: 66045508

Following gene: 66045510

Centisome position: 43.24

GC content: 62.58

Gene sequence:

>906_bases
ATGAACAAACCTCTCCCGGATGTTGCCCTGACGGAAATTTCCCCGGCGCTGGTGTCACTCGACTGGGTCGGCATGCAAGG
TGTGGAAGTGCCGATCAGACTGGCCGAAGCGAGCATTCGTCATCCTGTTCACGCGCACGTCGATCTGCAGGTCGATCTGG
CCGACCCGAGCGTCAAGGGCATCCATATGTCGCGACTCTATCGGCTGCTCGACGGCTATGCCGAGCGCCAGATCGTCAGC
CCCGATACGCTGGCTGCCTTGCTGGAAGCCATGGTCGAGAGTCACCTCGACTGCCACTCCAGTCACGCCCGGTTGACGCT
GAGCTTCAATCTGCTGTGCCGTCGACCGGCGTTGATTACCGAAGGGCTCAGCGGCTGGAAATCCTACCCCGTGAAGCTCG
ATGCCACCTGGCATGCCGGTCGGCTGTGCCTCGACAGTTCGGTGGATATCACCTACTCGTCCACCTGCCCGTGCTCGGCC
GCACTGTCTCGCCAATTGCTGGAAGAGGCATTTGCGGCGCGCTTCGGCAGGCAGTCGTTTGTCGATCCGATGCAGGTCGC
GACCTGGCTGCGCGAGAACGCATCGTTCGCCACGCCGCACAGCCAGCGCAGCGTTGCGACGGTGCAGGTACGGGTGGCAG
AGCAGGCGGCCGAACTGGGCTTGATGACGCTGATCGACCTGGTAGAGCAGGCGCTGGGCACCCCGGTGCAAACCGCCGTC
AAGCGTGCCGACGAACAGGCCTTTGCGCGGCTCAACGGCCAGAACCTGATGTACGTCGAAGACGCCGCACGCAAGGTCCA
GCAAGCACTCGAAGGCCGCTATGCAGCTTCCAGCGTCAGTGTCCGTCACTTTGAAAGCCTGCATCCGCACGATGCAGCCG
CCCAGACTTCCAACTACCTGTCCTGA

Upstream 100 bases:

>100_bases
ATAGTGTAACGAATTTATGGCCGTGCACTGTACGGCTGTGAACCGCCAACTTCAGGCTTCGCCCGCGTGGTGAAGTTCGC
CAACGAGACGAACGACGCAC

Downstream 100 bases:

>100_bases
GGTTTCATTCCGTGATCCGTAAAAATCCTTCCGGCCATCTGCCGGTCATTGCCGAGTCCGCCTACATCGATAAAACCGCG
ATCATCTGCGGCAAGGTGAT

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNKPLPDVALTEISPALVSLDWVGMQGVEVPIRLAEASIRHPVHAHVDLQVDLADPSVKGIHMSRLYRLLDGYAERQIVS
PDTLAALLEAMVESHLDCHSSHARLTLSFNLLCRRPALITEGLSGWKSYPVKLDATWHAGRLCLDSSVDITYSSTCPCSA
ALSRQLLEEAFAARFGRQSFVDPMQVATWLRENASFATPHSQRSVATVQVRVAEQAAELGLMTLIDLVEQALGTPVQTAV
KRADEQAFARLNGQNLMYVEDAARKVQQALEGRYAASSVSVRHFESLHPHDAAAQTSNYLS

Sequences:

>Translated_301_residues
MNKPLPDVALTEISPALVSLDWVGMQGVEVPIRLAEASIRHPVHAHVDLQVDLADPSVKGIHMSRLYRLLDGYAERQIVS
PDTLAALLEAMVESHLDCHSSHARLTLSFNLLCRRPALITEGLSGWKSYPVKLDATWHAGRLCLDSSVDITYSSTCPCSA
ALSRQLLEEAFAARFGRQSFVDPMQVATWLRENASFATPHSQRSVATVQVRVAEQAAELGLMTLIDLVEQALGTPVQTAV
KRADEQAFARLNGQNLMYVEDAARKVQQALEGRYAASSVSVRHFESLHPHDAAAQTSNYLS
>Mature_301_residues
MNKPLPDVALTEISPALVSLDWVGMQGVEVPIRLAEASIRHPVHAHVDLQVDLADPSVKGIHMSRLYRLLDGYAERQIVS
PDTLAALLEAMVESHLDCHSSHARLTLSFNLLCRRPALITEGLSGWKSYPVKLDATWHAGRLCLDSSVDITYSSTCPCSA
ALSRQLLEEAFAARFGRQSFVDPMQVATWLRENASFATPHSQRSVATVQVRVAEQAAELGLMTLIDLVEQALGTPVQTAV
KRADEQAFARLNGQNLMYVEDAARKVQQALEGRYAASSVSVRHFESLHPHDAAAQTSNYLS

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 33019; Mature: 33019

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPLPDVALTEISPALVSLDWVGMQGVEVPIRLAEASIRHPVHAHVDLQVDLADPSVKG
CCCCCCCHHHHHCCHHHEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCC
IHMSRLYRLLDGYAERQIVSPDTLAALLEAMVESHLDCHSSHARLTLSFNLLCRRPALIT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHCCCHHHH
EGLSGWKSYPVKLDATWHAGRLCLDSSVDITYSSTCPCSAALSRQLLEEAFAARFGRQSF
HHHHHHHCCCEEEECCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHC
VDPMQVATWLRENASFATPHSQRSVATVQVRVAEQAAELGLMTLIDLVEQALGTPVQTAV
CCHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KRADEQAFARLNGQNLMYVEDAARKVQQALEGRYAASSVSVRHFESLHPHDAAAQTSNYL
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHCCC
S
C
>Mature Secondary Structure
MNKPLPDVALTEISPALVSLDWVGMQGVEVPIRLAEASIRHPVHAHVDLQVDLADPSVKG
CCCCCCCHHHHHCCHHHEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCC
IHMSRLYRLLDGYAERQIVSPDTLAALLEAMVESHLDCHSSHARLTLSFNLLCRRPALIT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHCCCHHHH
EGLSGWKSYPVKLDATWHAGRLCLDSSVDITYSSTCPCSAALSRQLLEEAFAARFGRQSF
HHHHHHHCCCEEEECCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHC
VDPMQVATWLRENASFATPHSQRSVATVQVRVAEQAAELGLMTLIDLVEQALGTPVQTAV
CCHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KRADEQAFARLNGQNLMYVEDAARKVQQALEGRYAASSVSVRHFESLHPHDAAAQTSNYL
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA