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The map label for this gene is mcpB [H]

Identifier: 66045486

GI number: 66045486

Start: 2611442

End: 2613331

Strand: Direct

Name: mcpB [H]

Synonym: Psyr_2246

Alternate gene names: 66045486

Gene position: 2611442-2613331 (Clockwise)

Preceding gene: 66045482

Following gene: 66045487

Centisome position: 42.85

GC content: 59.42

Gene sequence:

>1890_bases
ATGAAAAGTCTGGGTTTCAGCAAAAAGATCCTTCTCGCCGCCGCATTGATTGTGGTCGTGGCGTTCAGTGTGTTCATTGT
CGTCAATGACTATCGACAACGTCAGTCGCTCAAATCCAGCGTCAAGTCCGAGTTGCAACAACTGGGTACGCTCACCACAC
AAAACATTCAGACCTGGCTGGAAAGCCGCATGCAATTGCTGCAGTCGATGTCGCAGCAAATCGCCGCGGATGGCAAGGAA
CTGCCCCAGTTGCAGCGTGCCATCGGCCTGCCTGCCTACAGCGAAAGCTTTCAACTGAGCTACTTTGGCAGCACCGAAGG
CGTGATGTTCTCGGTGCCGTCGGCCAATCGCCCGGCTGACTACGATCCGCGTGCGCGTGGCTGGTACAAGGCGGCACAGA
ATGCGCCGGGCACCATTGTGACCGAACCCTACATCGCGGCATCCTCTGGCAAGCTGGTCATGACCATGGCCACACCGGTC
AAGTTTCAGAATCAGTTCGTGGGCGTGGCCGGTGCTGATATCGCTCTGGACAACGTCACCAAGATCATCAACTCGCTGAA
CTTCGATGGCCATGGCTATGCATTCCTGGTCAGTGCCGACGGCAAGATTCTGGTGCATCCGGACAGCAAACTGGTGCTCA
AGAACATCAGTGAAGCCTACCCGACCAATACTCCGAAAATTACTACCGGCGTGACTGAAATCGACTCCGGTAAAAATCCG
GAGATCATTTCCTTCACGCCTGTTCAAGGTGTTTCGACGGCCAACTGGTACGTGGCACTGGTCCTCGAGCAGGATTCCGC
CTACGCCATGTTGGCCGAGTTCCGTGCCTCGGCCATCACCGCCATGGTGGTAGTGGTGGTGGTGATCATCCTGCTGCTGG
GCCTGTTGATTCGCGTGCTGATGCAACCCTTGCATCAGATGGGTCGGGCGATGCGTGACATCGCTGACGGCGAGGGCGAT
CTGACCAAGCGTCTGGCAATCACCTCGCAGGATGAGTTCGGCGAACTGGCCGAGTCGTTCAACCGTTTCGTCGAGCGTAT
TCACACCTCGATCCGTGAAGTGGCCTCGACTGCCGCGCAATTGGGCGAGGTTGCCACCCGGGTGGTCAAGGTCTCCAACG
CCTCGATGGGTAACTCCGACCAGCAGGCCAACCGTACCGAAAGCGTGGCGGCGGCGATCAACGAACTGGGCGCAGCAGCC
CAGGAAATCGCCCAGAATGCGGCACGCACCTCGCAGCAGTCGAGTGATGCGAGCGGCCTGGCCAGCGACGGCCAGAACGT
CGTGCAGCAGACCATCAAGGCGATGAACGAGCTGTCCGGGAAGATCAGCGAGTCGTGCGTGAACATCGAAAGCCTGAATG
GCAAGACTGCCAACATCGGGCAGATTCTCGAGGTGATCACCAGCATTTCCCAGCAGACCAACCTGCTGGCGCTCAACGCA
GCCATCGAGGCAGCGCGTGCCGGTGAAGCAGGGCGCGGGTTCGCGGTAGTGGCCGACGAAGTACGCAACCTGGCGCATCG
CACTCAGGATTCTGCCCAGCAAGTGCAGACCATGATCGAAGAGCTGCAGGTCGGCGCTCGCGACGCAGTGACCAACATGA
CCGAGAGCCAGCGTCAGAGCGAGGACAGCGTCGGCATCGCCAACCTGGCCGGCGAGCGTCTGGGCAGCGTGACCCGCCGC
ATCGAAGAGATCAACGGCATGAACCAGTCGGTCGCGGCGGCAACCGAGGAACAGACCTCGGTGGTCGAGTCGATCAATGT
CGACATCACTCACATCAACACCCTCAACCAGCTGGGTGTCGACAACCTGCGCCAGACCCTGGAAGCCTGCAACTCGCTGG
AAGAGCAGGCTGCCCGCCTGCAGCAACTGGTAGGCAGCTTCCGGATCTGA

Upstream 100 bases:

>100_bases
GGCCTGTGGGTTGTAACGTGAAATAGACGGCACTGTTGTGAAGTTTGATTGGCGATCCAGAGATCGTCCTTATTGGTTTT
TTGCCGTGGAAGTAACCGCT

Downstream 100 bases:

>100_bases
TCCGGCCACTTTCTGCGCCGCTGCTCATACCCGGGCGGCGCAGACAGAGCGTCTGGAATCGCATCCCGACGCCCTGCATC
GCTAACCATGTGCGCATCGC

Product: histidine kinase, HAMP region:Cache: chemotaxis sensory transducer

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MKSLGFSKKILLAAALIVVVAFSVFIVVNDYRQRQSLKSSVKSELQQLGTLTTQNIQTWLESRMQLLQSMSQQIAADGKE
LPQLQRAIGLPAYSESFQLSYFGSTEGVMFSVPSANRPADYDPRARGWYKAAQNAPGTIVTEPYIAASSGKLVMTMATPV
KFQNQFVGVAGADIALDNVTKIINSLNFDGHGYAFLVSADGKILVHPDSKLVLKNISEAYPTNTPKITTGVTEIDSGKNP
EIISFTPVQGVSTANWYVALVLEQDSAYAMLAEFRASAITAMVVVVVVIILLLGLLIRVLMQPLHQMGRAMRDIADGEGD
LTKRLAITSQDEFGELAESFNRFVERIHTSIREVASTAAQLGEVATRVVKVSNASMGNSDQQANRTESVAAAINELGAAA
QEIAQNAARTSQQSSDASGLASDGQNVVQQTIKAMNELSGKISESCVNIESLNGKTANIGQILEVITSISQQTNLLALNA
AIEAARAGEAGRGFAVVADEVRNLAHRTQDSAQQVQTMIEELQVGARDAVTNMTESQRQSEDSVGIANLAGERLGSVTRR
IEEINGMNQSVAAATEEQTSVVESINVDITHINTLNQLGVDNLRQTLEACNSLEEQAARLQQLVGSFRI

Sequences:

>Translated_629_residues
MKSLGFSKKILLAAALIVVVAFSVFIVVNDYRQRQSLKSSVKSELQQLGTLTTQNIQTWLESRMQLLQSMSQQIAADGKE
LPQLQRAIGLPAYSESFQLSYFGSTEGVMFSVPSANRPADYDPRARGWYKAAQNAPGTIVTEPYIAASSGKLVMTMATPV
KFQNQFVGVAGADIALDNVTKIINSLNFDGHGYAFLVSADGKILVHPDSKLVLKNISEAYPTNTPKITTGVTEIDSGKNP
EIISFTPVQGVSTANWYVALVLEQDSAYAMLAEFRASAITAMVVVVVVIILLLGLLIRVLMQPLHQMGRAMRDIADGEGD
LTKRLAITSQDEFGELAESFNRFVERIHTSIREVASTAAQLGEVATRVVKVSNASMGNSDQQANRTESVAAAINELGAAA
QEIAQNAARTSQQSSDASGLASDGQNVVQQTIKAMNELSGKISESCVNIESLNGKTANIGQILEVITSISQQTNLLALNA
AIEAARAGEAGRGFAVVADEVRNLAHRTQDSAQQVQTMIEELQVGARDAVTNMTESQRQSEDSVGIANLAGERLGSVTRR
IEEINGMNQSVAAATEEQTSVVESINVDITHINTLNQLGVDNLRQTLEACNSLEEQAARLQQLVGSFRI
>Mature_629_residues
MKSLGFSKKILLAAALIVVVAFSVFIVVNDYRQRQSLKSSVKSELQQLGTLTTQNIQTWLESRMQLLQSMSQQIAADGKE
LPQLQRAIGLPAYSESFQLSYFGSTEGVMFSVPSANRPADYDPRARGWYKAAQNAPGTIVTEPYIAASSGKLVMTMATPV
KFQNQFVGVAGADIALDNVTKIINSLNFDGHGYAFLVSADGKILVHPDSKLVLKNISEAYPTNTPKITTGVTEIDSGKNP
EIISFTPVQGVSTANWYVALVLEQDSAYAMLAEFRASAITAMVVVVVVIILLLGLLIRVLMQPLHQMGRAMRDIADGEGD
LTKRLAITSQDEFGELAESFNRFVERIHTSIREVASTAAQLGEVATRVVKVSNASMGNSDQQANRTESVAAAINELGAAA
QEIAQNAARTSQQSSDASGLASDGQNVVQQTIKAMNELSGKISESCVNIESLNGKTANIGQILEVITSISQQTNLLALNA
AIEAARAGEAGRGFAVVADEVRNLAHRTQDSAQQVQTMIEELQVGARDAVTNMTESQRQSEDSVGIANLAGERLGSVTRR
IEEINGMNQSVAAATEEQTSVVESINVDITHINTLNQLGVDNLRQTLEACNSLEEQAARLQQLVGSFRI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=393, Percent_Identity=30.2798982188295, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1787690, Length=361, Percent_Identity=32.1329639889197, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788195, Length=336, Percent_Identity=33.0357142857143, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1788194, Length=394, Percent_Identity=26.9035532994924, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789453, Length=356, Percent_Identity=23.314606741573, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 67622; Mature: 67622

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLGFSKKILLAAALIVVVAFSVFIVVNDYRQRQSLKSSVKSELQQLGTLTTQNIQTWL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
ESRMQLLQSMSQQIAADGKELPQLQRAIGLPAYSESFQLSYFGSTEGVMFSVPSANRPAD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCCCCCC
YDPRARGWYKAAQNAPGTIVTEPYIAASSGKLVMTMATPVKFQNQFVGVAGADIALDNVT
CCCCHHHHHHHHCCCCCCEEECCEEEECCCCEEEEEECCHHHHCCEEECCCCHHHHHHHH
KIINSLNFDGHGYAFLVSADGKILVHPDSKLVLKNISEAYPTNTPKITTGVTEIDSGKNP
HHHHHCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
EIISFTPVQGVSTANWYVALVLEQDSAYAMLAEFRASAITAMVVVVVVIILLLGLLIRVL
CEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQPLHQMGRAMRDIADGEGDLTKRLAITSQDEFGELAESFNRFVERIHTSIREVASTAAQ
HHHHHHHHHHHHHHCCCCCCHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEVATRVVKVSNASMGNSDQQANRTESVAAAINELGAAAQEIAQNAARTSQQSSDASGL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ASDGQNVVQQTIKAMNELSGKISESCVNIESLNGKTANIGQILEVITSISQQTNLLALNA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHCCEEEHHH
AIEAARAGEAGRGFAVVADEVRNLAHRTQDSAQQVQTMIEELQVGARDAVTNMTESQRQS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
EDSVGIANLAGERLGSVTRRIEEINGMNQSVAAATEEQTSVVESINVDITHINTLNQLGV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCH
DNLRQTLEACNSLEEQAARLQQLVGSFRI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSLGFSKKILLAAALIVVVAFSVFIVVNDYRQRQSLKSSVKSELQQLGTLTTQNIQTWL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
ESRMQLLQSMSQQIAADGKELPQLQRAIGLPAYSESFQLSYFGSTEGVMFSVPSANRPAD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCCCCCC
YDPRARGWYKAAQNAPGTIVTEPYIAASSGKLVMTMATPVKFQNQFVGVAGADIALDNVT
CCCCHHHHHHHHCCCCCCEEECCEEEECCCCEEEEEECCHHHHCCEEECCCCHHHHHHHH
KIINSLNFDGHGYAFLVSADGKILVHPDSKLVLKNISEAYPTNTPKITTGVTEIDSGKNP
HHHHHCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
EIISFTPVQGVSTANWYVALVLEQDSAYAMLAEFRASAITAMVVVVVVIILLLGLLIRVL
CEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQPLHQMGRAMRDIADGEGDLTKRLAITSQDEFGELAESFNRFVERIHTSIREVASTAAQ
HHHHHHHHHHHHHHCCCCCCHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEVATRVVKVSNASMGNSDQQANRTESVAAAINELGAAAQEIAQNAARTSQQSSDASGL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ASDGQNVVQQTIKAMNELSGKISESCVNIESLNGKTANIGQILEVITSISQQTNLLALNA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHCCEEEHHH
AIEAARAGEAGRGFAVVADEVRNLAHRTQDSAQQVQTMIEELQVGARDAVTNMTESQRQS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
EDSVGIANLAGERLGSVTRRIEEINGMNQSVAAATEEQTSVVESINVDITHINTLNQLGV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCH
DNLRQTLEACNSLEEQAARLQQLVGSFRI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]