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The map label for this gene is ttdR [H]

Identifier: 66045459

GI number: 66045459

Start: 2578633

End: 2579586

Strand: Direct

Name: ttdR [H]

Synonym: Psyr_2219

Alternate gene names: 66045459

Gene position: 2578633-2579586 (Clockwise)

Preceding gene: 66045456

Following gene: 66045471

Centisome position: 42.32

GC content: 61.84

Gene sequence:

>954_bases
TTGCCTCAGGTGAAACAAAAGCCTCAGTATTGGCAACTATTGATTGCTTATATCGGACGAATCGTGGATCGGATCATAGC
GGCACGGGTATTCATCGCCATCAACGACAGGGGCAGCCTCATTGCCGCCGCCGAGGCGCTGGATATGTCTCGGGCAATGG
TCACGCGGTATTTGGCGCAGATGGAAAGCTGGGCCGGAGCGCGACTGCTGCACCGGACTACGCGCAAGCTCGGCTTGACC
GCCCCCGGGCAGGTGACGCTGTTGCGGTGTCAGCAATTGGTCGAGCTTGCCGACGCGGTGCCGCTGGCGGCCGATACGCA
AGTCGACGAGCCGCGCGGCATGCTGCGCATCGCCTGTTCGCAGTCACTGGCCCTGGCCGTTCTGGCACCCGCGGTGACGG
CTTACCTGCAACGCTATCCCGGCACCTCGGCAGACCTGCTTATCGGTAACGAGGCCGTGGATCTGGTCAGCGAGCGAATC
GATCTGGCGATCCGCATCACTAATCAATTGGACCCCAATGTAATTGCCCGTCCGCTGGGGCAGTGCGCTTCGGTGGTGTG
CGCTGCTCCAGCCTATCTCGCCGTGCACGGCACCCCGTCCAGGCCGCAGGAACTGACTGCCCATAACTGCCTGACCTATT
CGTACTTCGGCAAGAGCCTCTGGGAATTTACCCGCCAGCAGATGCCGCTCAGTGTGCCGGTCGGCGGCAACCTGAGTGCC
AACGATTCAGTGGTGCTGCTGGAGGCCGCAGTGGCGGGCGCCGGTATCAGCCTGCAACCGGTGCATTCGGCAGCGCCGCT
GATTGCGAGCGGCAAGCTGATCGCCCTGATGCCGGAGTACCAGCCACGGGCACTGGGGATACACGCGATCTACACTTCGC
GGCACCACCAGTCGGCAACGCTGCGCACTTTTCTGGATTTTCTGACTGAATGGTTTGAGAGGGACGGAGATTAG

Upstream 100 bases:

>100_bases
CTGCGAGAGGGAACAGAGCAGCGAAGGACAGGGCAAGCATGGATTTACGCGACATGGGGTATGACCTTGGTTCGGGCAGG
ACTGAGGTGGTTATCTTAAG

Downstream 100 bases:

>100_bases
ATCACCTGCTGCGTCCAGAACGGCATGCCCGCGTGGAGCATGGGCACGATAGGGGATGCCCATCGTTCCTCACGCTCCGT
GTGCGCGGTATCAGGTCTTG

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MPQVKQKPQYWQLLIAYIGRIVDRIIAARVFIAINDRGSLIAAAEALDMSRAMVTRYLAQMESWAGARLLHRTTRKLGLT
APGQVTLLRCQQLVELADAVPLAADTQVDEPRGMLRIACSQSLALAVLAPAVTAYLQRYPGTSADLLIGNEAVDLVSERI
DLAIRITNQLDPNVIARPLGQCASVVCAAPAYLAVHGTPSRPQELTAHNCLTYSYFGKSLWEFTRQQMPLSVPVGGNLSA
NDSVVLLEAAVAGAGISLQPVHSAAPLIASGKLIALMPEYQPRALGIHAIYTSRHHQSATLRTFLDFLTEWFERDGD

Sequences:

>Translated_317_residues
MPQVKQKPQYWQLLIAYIGRIVDRIIAARVFIAINDRGSLIAAAEALDMSRAMVTRYLAQMESWAGARLLHRTTRKLGLT
APGQVTLLRCQQLVELADAVPLAADTQVDEPRGMLRIACSQSLALAVLAPAVTAYLQRYPGTSADLLIGNEAVDLVSERI
DLAIRITNQLDPNVIARPLGQCASVVCAAPAYLAVHGTPSRPQELTAHNCLTYSYFGKSLWEFTRQQMPLSVPVGGNLSA
NDSVVLLEAAVAGAGISLQPVHSAAPLIASGKLIALMPEYQPRALGIHAIYTSRHHQSATLRTFLDFLTEWFERDGD
>Mature_316_residues
PQVKQKPQYWQLLIAYIGRIVDRIIAARVFIAINDRGSLIAAAEALDMSRAMVTRYLAQMESWAGARLLHRTTRKLGLTA
PGQVTLLRCQQLVELADAVPLAADTQVDEPRGMLRIACSQSLALAVLAPAVTAYLQRYPGTSADLLIGNEAVDLVSERID
LAIRITNQLDPNVIARPLGQCASVVCAAPAYLAVHGTPSRPQELTAHNCLTYSYFGKSLWEFTRQQMPLSVPVGGNLSAN
DSVVLLEAAVAGAGISLQPVHSAAPLIASGKLIALMPEYQPRALGIHAIYTSRHHQSATLRTFLDFLTEWFERDGD

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=34.2465753424658, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=30.7432432432432, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786401, Length=284, Percent_Identity=30.6338028169014, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=29.7945205479452, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787128, Length=284, Percent_Identity=26.7605633802817, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787589, Length=284, Percent_Identity=26.7605633802817, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=25.2, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788706, Length=277, Percent_Identity=24.187725631769, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34460; Mature: 34329

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQVKQKPQYWQLLIAYIGRIVDRIIAARVFIAINDRGSLIAAAEALDMSRAMVTRYLAQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHH
MESWAGARLLHRTTRKLGLTAPGQVTLLRCQQLVELADAVPLAADTQVDEPRGMLRIACS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHH
QSLALAVLAPAVTAYLQRYPGTSADLLIGNEAVDLVSERIDLAIRITNQLDPNVIARPLG
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCEEEEECCCCCCHHHHHHHH
QCASVVCAAPAYLAVHGTPSRPQELTAHNCLTYSYFGKSLWEFTRQQMPLSVPVGGNLSA
HHHHHHHCCCEEEEEECCCCCCHHHHHHHCEEHHHHHHHHHHHHHHCCCEECCCCCCCCC
NDSVVLLEAAVAGAGISLQPVHSAAPLIASGKLIALMPEYQPRALGIHAIYTSRHHQSAT
CCCEEEEEEHHCCCCCEECCCCCCCCEEECCCEEEECCCCCCCCEEEEEEEECCCCCHHH
LRTFLDFLTEWFERDGD
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PQVKQKPQYWQLLIAYIGRIVDRIIAARVFIAINDRGSLIAAAEALDMSRAMVTRYLAQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHH
MESWAGARLLHRTTRKLGLTAPGQVTLLRCQQLVELADAVPLAADTQVDEPRGMLRIACS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHH
QSLALAVLAPAVTAYLQRYPGTSADLLIGNEAVDLVSERIDLAIRITNQLDPNVIARPLG
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCEEEEECCCCCCHHHHHHHH
QCASVVCAAPAYLAVHGTPSRPQELTAHNCLTYSYFGKSLWEFTRQQMPLSVPVGGNLSA
HHHHHHHCCCEEEEEECCCCCCHHHHHHHCEEHHHHHHHHHHHHHHCCCEECCCCCCCCC
NDSVVLLEAAVAGAGISLQPVHSAAPLIASGKLIALMPEYQPRALGIHAIYTSRHHQSAT
CCCEEEEEEHHCCCCCEECCCCCCCCEEECCCEEEECCCCCCCCEEEEEEEECCCCCHHH
LRTFLDFLTEWFERDGD
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]