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The map label for this gene is sixA [H]

Identifier: 66045264

GI number: 66045264

Start: 2349422

End: 2349877

Strand: Direct

Name: sixA [H]

Synonym: Psyr_2024

Alternate gene names: 66045264

Gene position: 2349422-2349877 (Clockwise)

Preceding gene: 66045263

Following gene: 66045265

Centisome position: 38.55

GC content: 62.5

Gene sequence:

>456_bases
ATGAAGGTCTGGGTATTGCGTCATGGCGAAGCGCAGTCGCGGGCGCGCAGTGATGCCGAGCGCGAGTTGACTGCACATGG
GCGTGAGGAAGTGCTGAAAAGTGCGCTGCACCTGACAGACAAGCCCGTGCAACGGATCATTGCCAGCCCCTACGTGCGTG
CACAACAGACTGCCGAGCTGGTGCGTCAGTCGTTGGCATTCGATGGCTCGATCGTCACCGCGCCCTGGCTTACCCCCGAC
AGCAGCCCGCGTGAGGTGCTGGCGCAACTGGACAAGCTGGGTGTCGATGAAGTACTGCTGGTCAGCCATCAGCCTTTGGT
GGGCGAACTGATCGGGGTACTGGCGCATGGCAGTCCGCAACAGGCCGAGCCGATGAGCACGGCCAGTCTTGCCGAACTGG
AAGGCGAGTTCGTAGTGGCAGGCGGCATGCGCCTCAACAGCGTCAGGCACGTCTGA

Upstream 100 bases:

>100_bases
GGCCTTTCGGCGACTGGCCAGCGCCGCGTGCGCCCGAAGGCGAGGTGGCCCATCATGTCCCGCCAGCGGCACAGCCGGTG
CGCAATGAGGCGCCAAAGCC

Downstream 100 bases:

>100_bases
ACAGCCTGTACGCGCAATGAATGACCGCCGCGAATGCGGCTCTCCCGGGAAAAGGATTCAGCATGAGCATATGGCGTCAG
GCTCCCGATATCGAAGCCCT

Product: phosphohistidine phosphatase SixA

Products: NA

Alternate protein names: RX6 [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKVWVLRHGEAQSRARSDAERELTAHGREEVLKSALHLTDKPVQRIIASPYVRAQQTAELVRQSLAFDGSIVTAPWLTPD
SSPREVLAQLDKLGVDEVLLVSHQPLVGELIGVLAHGSPQQAEPMSTASLAELEGEFVVAGGMRLNSVRHV

Sequences:

>Translated_151_residues
MKVWVLRHGEAQSRARSDAERELTAHGREEVLKSALHLTDKPVQRIIASPYVRAQQTAELVRQSLAFDGSIVTAPWLTPD
SSPREVLAQLDKLGVDEVLLVSHQPLVGELIGVLAHGSPQQAEPMSTASLAELEGEFVVAGGMRLNSVRHV
>Mature_151_residues
MKVWVLRHGEAQSRARSDAERELTAHGREEVLKSALHLTDKPVQRIIASPYVRAQQTAELVRQSLAFDGSIVTAPWLTPD
SSPREVLAQLDKLGVDEVLLVSHQPLVGELIGVLAHGSPQQAEPMSTASLAELEGEFVVAGGMRLNSVRHV

Specific function: Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His- Asp phosphorelay [H]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=134, Percent_Identity=38.0597014925373, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 16443; Mature: 16443

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVWVLRHGEAQSRARSDAERELTAHGREEVLKSALHLTDKPVQRIIASPYVRAQQTAEL
CEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
VRQSLAFDGSIVTAPWLTPDSSPREVLAQLDKLGVDEVLLVSHQPLVGELIGVLAHGSPQ
HHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCC
QAEPMSTASLAELEGEFVVAGGMRLNSVRHV
CCCCCCHHHHHHHCCCEEEECCEECCCCCCC
>Mature Secondary Structure
MKVWVLRHGEAQSRARSDAERELTAHGREEVLKSALHLTDKPVQRIIASPYVRAQQTAEL
CEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
VRQSLAFDGSIVTAPWLTPDSSPREVLAQLDKLGVDEVLLVSHQPLVGELIGVLAHGSPQ
HHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCC
QAEPMSTASLAELEGEFVVAGGMRLNSVRHV
CCCCCCHHHHHHHCCCEEEECCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9489669; 9205837; 9278503 [H]