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The map label for this gene is gpsA [H]

Identifier: 66045262

GI number: 66045262

Start: 2348031

End: 2349056

Strand: Direct

Name: gpsA [H]

Synonym: Psyr_2022

Alternate gene names: 66045262

Gene position: 2348031-2349056 (Clockwise)

Preceding gene: 66045258

Following gene: 66045263

Centisome position: 38.53

GC content: 60.62

Gene sequence:

>1026_bases
ATGACCACACAGCAACCCGTCGCGGTGCTTGGCGGTGGCAGCTTCGGTACGGCCATTGCCAATCTGCTGGCCGAGAACGG
CCATCAGGTTCGTCAGTGGATGCGCGATCCGGAGCAGGCTGAGGCCATTCGCGTCAATCGTGAAAACCCCCGCTACCTCA
AGGGCATCAGGATTCGTCCTGAAGTCGAGCCGGTCACCGACCTGACGGCGGTGCTCGACGCCAGCGAACTGATCTTCGTC
GCCTTGCCATCGAGTGCCTTGCGCTCGGTGTTGTCGCCTCATGTCGCGCGCCTGAATGGCAAGATGCTGGTGAGCCTGAC
CAAGGGTATCGAAGCGCAGAGCTTCAAGCTCATGAGTCAGATCCTCGAAGAGATCGTCCCGCAGGCGCGTATCGGCGTGT
TGTCCGGGCCCAATCTGGCGCGGGAAATCGCCGAACATGCGCTGACCGCAACAGTGGTTGCCAGCGAAGACGAGGCACTG
TGTCAGGAGGTTCAGGCTGCATTGCACGGGCGAACCTTTCGCGTCTATGCCAGCAATGACCGGTTTGGTGTCGAACTGGG
CGGGGCCCTGAAGAACGTCTACGCGATTATTGCCGGCATGGCGGTGGCGCTGGACATGGGCGAAAACACCAAAAGCATGC
TGATCACCCGGGCGCTGGCGGAAATGACCCGGTTTGCGGTCAGCCAGGGCGCCAACCCGATGACCTTTCTGGGCCTGGCC
GGGGTGGGCGATCTCATCGTCACCTGTTCCTCGCCGAAAAGCCGCAACTATCAGGTCGGTTTTGCGCTGGGCCAGGGGCT
GACGCTGGATGAAGCGGTCACGCGTTTGGGCGAGGTGGCCGAGGGTGTGAACACCCTCAAGGTGCTTAAGGTCAAAGCGC
AGGAAGTGCAGGTCTATATGCCATTGGTCGCGGGGCTGCATGCGATTCTTTTTGAAGGCCGTACGCTCAGCCAGGTCATT
GAGGCGCTGATGCGGGCCGAGCCCAAGACGGACGTCGATTTCATTTCGATTACCGGCTTTAATTGA

Upstream 100 bases:

>100_bases
GTACGGAGTGCGTAACCGATCAGCTTTGTCGCTGGCCGATAACGTGTTGCTCCGTATAATGACGGCATCGCCACTTGAAT
GGCTCTGGATGGATAGTTTT

Downstream 100 bases:

>100_bases
ATTCAGTCTGATCAGGAGAAGGTCTTGAACGAGTCGAAAATCCAGCACAACGAATCGATCCTGCTGCGCATTCTGTGGAT
GCTGCTGTTTCTGGGGGTAT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTTQQPVAVLGGGSFGTAIANLLAENGHQVRQWMRDPEQAEAIRVNRENPRYLKGIRIRPEVEPVTDLTAVLDASELIFV
ALPSSALRSVLSPHVARLNGKMLVSLTKGIEAQSFKLMSQILEEIVPQARIGVLSGPNLAREIAEHALTATVVASEDEAL
CQEVQAALHGRTFRVYASNDRFGVELGGALKNVYAIIAGMAVALDMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLA
GVGDLIVTCSSPKSRNYQVGFALGQGLTLDEAVTRLGEVAEGVNTLKVLKVKAQEVQVYMPLVAGLHAILFEGRTLSQVI
EALMRAEPKTDVDFISITGFN

Sequences:

>Translated_341_residues
MTTQQPVAVLGGGSFGTAIANLLAENGHQVRQWMRDPEQAEAIRVNRENPRYLKGIRIRPEVEPVTDLTAVLDASELIFV
ALPSSALRSVLSPHVARLNGKMLVSLTKGIEAQSFKLMSQILEEIVPQARIGVLSGPNLAREIAEHALTATVVASEDEAL
CQEVQAALHGRTFRVYASNDRFGVELGGALKNVYAIIAGMAVALDMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLA
GVGDLIVTCSSPKSRNYQVGFALGQGLTLDEAVTRLGEVAEGVNTLKVLKVKAQEVQVYMPLVAGLHAILFEGRTLSQVI
EALMRAEPKTDVDFISITGFN
>Mature_340_residues
TTQQPVAVLGGGSFGTAIANLLAENGHQVRQWMRDPEQAEAIRVNRENPRYLKGIRIRPEVEPVTDLTAVLDASELIFVA
LPSSALRSVLSPHVARLNGKMLVSLTKGIEAQSFKLMSQILEEIVPQARIGVLSGPNLAREIAEHALTATVVASEDEALC
QEVQAALHGRTFRVYASNDRFGVELGGALKNVYAIIAGMAVALDMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLAG
VGDLIVTCSSPKSRNYQVGFALGQGLTLDEAVTRLGEVAEGVNTLKVLKVKAQEVQVYMPLVAGLHAILFEGRTLSQVIE
ALMRAEPKTDVDFISITGFN

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=345, Percent_Identity=29.8550724637681, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI24307999, Length=345, Percent_Identity=30.4347826086957, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1790037, Length=313, Percent_Identity=38.9776357827476, Blast_Score=218, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=27.3239436619718, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32564399, Length=352, Percent_Identity=28.125, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193210136, Length=363, Percent_Identity=27.5482093663912, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32564403, Length=361, Percent_Identity=27.7008310249307, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193210134, Length=350, Percent_Identity=26.5714285714286, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324513, Length=360, Percent_Identity=25.8333333333333, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320181, Length=361, Percent_Identity=28.2548476454294, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136204, Length=351, Percent_Identity=26.4957264957265, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136202, Length=351, Percent_Identity=26.4957264957265, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136200, Length=351, Percent_Identity=26.4957264957265, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI22026922, Length=343, Percent_Identity=25.0728862973761, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45551945, Length=350, Percent_Identity=24, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362270, Length=242, Percent_Identity=25.6198347107438, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648969, Length=308, Percent_Identity=25, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36621; Mature: 36490

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQQPVAVLGGGSFGTAIANLLAENGHQVRQWMRDPEQAEAIRVNRENPRYLKGIRIRP
CCCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHCCCCHHHEEEECCCCCCHHCCCCCCC
EVEPVTDLTAVLDASELIFVALPSSALRSVLSPHVARLNGKMLVSLTKGIEAQSFKLMSQ
CCCCHHHHHHHHCCCCEEEEEECHHHHHHHHCHHHHHCCCCEEEEECCCCCHHHHHHHHH
ILEEIVPQARIGVLSGPNLAREIAEHALTATVVASEDEALCQEVQAALHGRTFRVYASND
HHHHHCCHHHEEECCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCEEEEEECCC
RFGVELGGALKNVYAIIAGMAVALDMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLA
CCCEEHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
GVGDLIVTCSSPKSRNYQVGFALGQGLTLDEAVTRLGEVAEGVNTLKVLKVKAQEVQVYM
CCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHEEHHHHHHHHH
PLVAGLHAILFEGRTLSQVIEALMRAEPKTDVDFISITGFN
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEECCC
>Mature Secondary Structure 
TTQQPVAVLGGGSFGTAIANLLAENGHQVRQWMRDPEQAEAIRVNRENPRYLKGIRIRP
CCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHCCCCHHHEEEECCCCCCHHCCCCCCC
EVEPVTDLTAVLDASELIFVALPSSALRSVLSPHVARLNGKMLVSLTKGIEAQSFKLMSQ
CCCCHHHHHHHHCCCCEEEEEECHHHHHHHHCHHHHHCCCCEEEEECCCCCHHHHHHHHH
ILEEIVPQARIGVLSGPNLAREIAEHALTATVVASEDEALCQEVQAALHGRTFRVYASND
HHHHHCCHHHEEECCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCEEEEEECCC
RFGVELGGALKNVYAIIAGMAVALDMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLA
CCCEEHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
GVGDLIVTCSSPKSRNYQVGFALGQGLTLDEAVTRLGEVAEGVNTLKVLKVKAQEVQVYM
CCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHEEHHHHHHHHH
PLVAGLHAILFEGRTLSQVIEALMRAEPKTDVDFISITGFN
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA