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The map label for this gene is frr

Identifier: 66044594

GI number: 66044594

Start: 1525960

End: 1526517

Strand: Direct

Name: frr

Synonym: Psyr_1346

Alternate gene names: 66044594

Gene position: 1525960-1526517 (Clockwise)

Preceding gene: 66044593

Following gene: 66044595

Centisome position: 25.04

GC content: 58.06

Gene sequence:

>558_bases
ATGATCAACGAAATCAAGAAAGATGCTCAGACCCGTATGCAGAAGAGTCTGGAGTCGCTGACCCATGCCTTCACCCGTAT
CCGTACCGGCAAGGCGCATCCGAGCATCCTGGGTGGTGTGATGGTTCCTTACTACGGCGCAGATACCCCGCTGAGCCAGG
TGGCCAACGTGACCGTCAAGGACTCGCGTACCCTTCAGGTCGTGGCGTTCGAGCGCAACATGCTGGCGGCTGTCGACAAG
GCCATCCAGAGCTCCGGTCTGGGCTTCAATCCGACCAACCTGGGTGAGTTGCTGCTGATCTCCATGCCGGCGCTGACCGA
AGAAACCCGCAAGGGCTTCACCAAGCAGGCGCGCGATGCTGCAGAAGATGCCCGTGTGGCCGTCCGTAACATCCGCCGTG
ACGCCTTGAGCCAGTTGAAAGACCTGGTCAAGGAGAAGGAAATCAGCGAAGACGAAGAGCGCCGTGCGGCTGACGACGTA
CAGAAGCTGACTGACAAGTTCGTGGCGGAAATCGAAGTTGCGGTCAAGCAGAAAGAAGCCGATCTGATGGCTGTTTAA

Upstream 100 bases:

>100_bases
ACAAGATGCCATTGCGCGTCTTCAACATGAACAAGCCGGGTGCCCTTCTGAATATCGTCCATGGTGGCGCTGAAGGGACC
CTGATCGAGGAAGCACAATA

Downstream 100 bases:

>100_bases
GGTTTCGGACGCTTTCATGGAAAAGATAAAACCGGCCGTGCCGTCTTCGGTGCCGCGCCATGTCGCGATTATCATGGATG
GTAATAATCGCTGGGCCAAG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINEIKKDAQTRMQKSLESLTHAFTRIRTGKAHPSILGGVMVPYYGADTPLSQVANVTVKDSRTLQVVAFERNMLAAVDK
AIQSSGLGFNPTNLGELLLISMPALTEETRKGFTKQARDAAEDARVAVRNIRRDALSQLKDLVKEKEISEDEERRAADDV
QKLTDKFVAEIEVAVKQKEADLMAV

Sequences:

>Translated_185_residues
MINEIKKDAQTRMQKSLESLTHAFTRIRTGKAHPSILGGVMVPYYGADTPLSQVANVTVKDSRTLQVVAFERNMLAAVDK
AIQSSGLGFNPTNLGELLLISMPALTEETRKGFTKQARDAAEDARVAVRNIRRDALSQLKDLVKEKEISEDEERRAADDV
QKLTDKFVAEIEVAVKQKEADLMAV
>Mature_185_residues
MINEIKKDAQTRMQKSLESLTHAFTRIRTGKAHPSILGGVMVPYYGADTPLSQVANVTVKDSRTLQVVAFERNMLAAVDK
AIQSSGLGFNPTNLGELLLISMPALTEETRKGFTKQARDAAEDARVAVRNIRRDALSQLKDLVKEKEISEDEERRAADDV
QKLTDKFVAEIEVAVKQKEADLMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=172, Percent_Identity=28.4883720930233, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=54.6448087431694, Blast_Score=203, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=27.1676300578035, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PSE14 (Q48F62)

Other databases:

- EMBL:   CP000058
- RefSeq:   YP_275975.1
- ProteinModelPortal:   Q48F62
- SMR:   Q48F62
- STRING:   Q48F62
- GeneID:   3555924
- GenomeReviews:   CP000058_GR
- KEGG:   psp:PSPPH_3837
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q48F62
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20484; Mature: 20484

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEIKKDAQTRMQKSLESLTHAFTRIRTGKAHPSILGGVMVPYYGADTPLSQVANVTVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHCCCCCCCCHHHHHCCEEC
DSRTLQVVAFERNMLAAVDKAIQSSGLGFNPTNLGELLLISMPALTEETRKGFTKQARDA
CCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
AEDARVAVRNIRRDALSQLKDLVKEKEISEDEERRAADDVQKLTDKFVAEIEVAVKQKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLMAV
HHCCC
>Mature Secondary Structure
MINEIKKDAQTRMQKSLESLTHAFTRIRTGKAHPSILGGVMVPYYGADTPLSQVANVTVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHCCCCCCCCHHHHHCCEEC
DSRTLQVVAFERNMLAAVDKAIQSSGLGFNPTNLGELLLISMPALTEETRKGFTKQARDA
CCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
AEDARVAVRNIRRDALSQLKDLVKEKEISEDEERRAADDVQKLTDKFVAEIEVAVKQKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLMAV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA