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The map label for this gene is insK [H]

Identifier: 66044427

GI number: 66044427

Start: 1330328

End: 1331164

Strand: Reverse

Name: insK [H]

Synonym: Psyr_1176

Alternate gene names: 66044427

Gene position: 1331164-1330328 (Counterclockwise)

Preceding gene: 66044428

Following gene: 66044425

Centisome position: 21.84

GC content: 50.66

Gene sequence:

>837_bases
ATGGAACTGAGGCCTTTACATCCTCTGGACGGCCTGCTGAAGTTTGCCGGTCTGGCACGCAGCACTTTTTACTATCAACA
AAAGGTACTGCTGGTAGATGACAAATACGCCGGGCTGAAAGACCTGATTCAGGCAACTTTCTACGAGCACAAGGGCCGGT
ATGGCTATCGTCGCATCACGGCAGCTTTGCGCAGGGCGGGCCATCTTGTGAACCACAAGACGGTGCAGAAACTAATGGGG
CAGCTAGGCCTGAAGAGCCTGATACGCGTGAAGAAATACCGTTCCTACAAAGGCGAAACAGGCAAGGCCGCGCCTAACCT
GCTAAAGCGTGATTTCAAAGCGCAATACCTTAACCAGAAATGGGCCACCGACGTGACCGAATTCAAAGTAGGAGGCCAGA
AACTTTATCTGTCGCCGATCATGGATCTGTACAGCGGCGAAATCATTTCCTATGCGATTGCCAGGCGCCCGCTGTACTCC
ATGGTCGACGAAATGCTTGAAGGAGCATTTAAGCGGCTTGGACCGCATGAAAAGCCGATTTTGCATTCCGACCAGGGCTG
GCAATATCGGATGCCTATTTACCAGCGACTGCTCAATGAGAATTCGATCGCAGCCAGCATGTCGCGCAAGGGTAACTGCT
ACGACAACGCGGCTATTGAGAGCTTTTTTAGCACGCTGAAATCCGAATTTTTCTACCTGAACAAATTTAACGATCTGGAT
GAGCTTCAAGCGGGTATCGAAGAGTACATTGAGTATTACAATCACTCACGCATAAAACTGAAGCTTAACGGCCTGAGTCC
TGTGGAATACAGAATGCAGGCCGCCAAGGCAGCGTAG

Upstream 100 bases:

>100_bases
AGGTGAAGCAACTGCGGATGGAGGTCGATTATCTAAAAAAGCTCGATGCCTTGGTTCAGAAGAAGCAACGAATAGCGCAG
CAGAAAAAGCGCAAATCGTG

Downstream 100 bases:

>100_bases
GTGGATAATTGTCCAACCTTCGGGGGTCACACCAGAGCGTGCGGAACGATCATCGCAACTATCGTACGACGCTCTGCGTC
GTATGCCGTTCCGGAGGCTC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MELRPLHPLDGLLKFAGLARSTFYYQQKVLLVDDKYAGLKDLIQATFYEHKGRYGYRRITAALRRAGHLVNHKTVQKLMG
QLGLKSLIRVKKYRSYKGETGKAAPNLLKRDFKAQYLNQKWATDVTEFKVGGQKLYLSPIMDLYSGEIISYAIARRPLYS
MVDEMLEGAFKRLGPHEKPILHSDQGWQYRMPIYQRLLNENSIAASMSRKGNCYDNAAIESFFSTLKSEFFYLNKFNDLD
ELQAGIEEYIEYYNHSRIKLKLNGLSPVEYRMQAAKAA

Sequences:

>Translated_278_residues
MELRPLHPLDGLLKFAGLARSTFYYQQKVLLVDDKYAGLKDLIQATFYEHKGRYGYRRITAALRRAGHLVNHKTVQKLMG
QLGLKSLIRVKKYRSYKGETGKAAPNLLKRDFKAQYLNQKWATDVTEFKVGGQKLYLSPIMDLYSGEIISYAIARRPLYS
MVDEMLEGAFKRLGPHEKPILHSDQGWQYRMPIYQRLLNENSIAASMSRKGNCYDNAAIESFFSTLKSEFFYLNKFNDLD
ELQAGIEEYIEYYNHSRIKLKLNGLSPVEYRMQAAKAA
>Mature_278_residues
MELRPLHPLDGLLKFAGLARSTFYYQQKVLLVDDKYAGLKDLIQATFYEHKGRYGYRRITAALRRAGHLVNHKTVQKLMG
QLGLKSLIRVKKYRSYKGETGKAAPNLLKRDFKAQYLNQKWATDVTEFKVGGQKLYLSPIMDLYSGEIISYAIARRPLYS
MVDEMLEGAFKRLGPHEKPILHSDQGWQYRMPIYQRLLNENSIAASMSRKGNCYDNAAIESFFSTLKSEFFYLNKFNDLD
ELQAGIEEYIEYYNHSRIKLKLNGLSPVEYRMQAAKAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=232, Percent_Identity=29.3103448275862, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1789981, Length=273, Percent_Identity=59.3406593406593, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1788405, Length=268, Percent_Identity=32.4626865671642, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787263, Length=268, Percent_Identity=32.4626865671642, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786753, Length=268, Percent_Identity=32.4626865671642, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786570, Length=268, Percent_Identity=32.4626865671642, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786490, Length=268, Percent_Identity=32.4626865671642, Blast_Score=131, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32165; Mature: 32165

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRPLHPLDGLLKFAGLARSTFYYQQKVLLVDDKYAGLKDLIQATFYEHKGRYGYRRIT
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHH
AALRRAGHLVNHKTVQKLMGQLGLKSLIRVKKYRSYKGETGKAAPNLLKRDFKAQYLNQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
WATDVTEFKVGGQKLYLSPIMDLYSGEIISYAIARRPLYSMVDEMLEGAFKRLGPHEKPI
HHCCHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCC
LHSDQGWQYRMPIYQRLLNENSIAASMSRKGNCYDNAAIESFFSTLKSEFFYLNKFNDLD
EECCCCCEECCHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
ELQAGIEEYIEYYNHSRIKLKLNGLSPVEYRMQAAKAA
HHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MELRPLHPLDGLLKFAGLARSTFYYQQKVLLVDDKYAGLKDLIQATFYEHKGRYGYRRIT
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHH
AALRRAGHLVNHKTVQKLMGQLGLKSLIRVKKYRSYKGETGKAAPNLLKRDFKAQYLNQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
WATDVTEFKVGGQKLYLSPIMDLYSGEIISYAIARRPLYSMVDEMLEGAFKRLGPHEKPI
HHCCHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCC
LHSDQGWQYRMPIYQRLLNENSIAASMSRKGNCYDNAAIESFFSTLKSEFFYLNKFNDLD
EECCCCCEECCHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
ELQAGIEEYIEYYNHSRIKLKLNGLSPVEYRMQAAKAA
HHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]