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The map label for this gene is ilvH [H]

Identifier: 66044102

GI number: 66044102

Start: 959899

End: 960390

Strand: Direct

Name: ilvH [H]

Synonym: Psyr_0847

Alternate gene names: 66044102

Gene position: 959899-960390 (Clockwise)

Preceding gene: 66044101

Following gene: 66044103

Centisome position: 15.75

GC content: 58.54

Gene sequence:

>492_bases
ATGCGCCATATCATTTCCCTGCTGCTGGAAAACGAACCGGGTGCACTGTCGCGCGTCGTTGGTCTGTTCTCCCAGCGTAA
CTACAACATCGAAAGTCTGACGGTTGCGCCGACCGAAGACCCGACCCTGTCGCGTCTGACGCTCACCACCGTAGGTCATG
ATGAGGTGATCGAGCAGATCACCAAGAACCTCAACAAGCTCATCGAAGTGGTCAAGCTGGTCGACCTGTCGGAAAGCGCT
CACATCGAGCGCGAACTGATGCTGGTCAAGGTCAAGGCCACCGGCGCGCAGCGTGCGGAGATCAAGCGCACCACGGATAT
CTTCCGCGGGCAGATCGTCGACGTGACCGCCAGCGTCTACACCGTGCAACTGAGCGGCACGAGCGACAAACTGGACAGCT
TCATTCAGGCCATCGGCACCGCCGCTATCCTGGAAACAGTACGCAGTGGCGTAACGGGCATTGCCCGTGGCGACAAAGTG
CTGAGCATTTAA

Upstream 100 bases:

>100_bases
TGGATATTCAGGTCGATGTGACCGAGCACGTCTATCCGATGCAAATCAAGGACGGCTCCATGCGCGATATGTGGTTGAGC
AAGACGGAGCGGACATAATC

Downstream 100 bases:

>100_bases
ATCAATTAAGCAAATGGCCTGCGTGGCCAAGATAACAGGGGATTTCCATGAAAGTTTTCTACGACAAAGACTGTGACCTT
TCGATCATTCAGGGCAAGAA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRHIISLLLENEPGALSRVVGLFSQRNYNIESLTVAPTEDPTLSRLTLTTVGHDEVIEQITKNLNKLIEVVKLVDLSESA
HIERELMLVKVKATGAQRAEIKRTTDIFRGQIVDVTASVYTVQLSGTSDKLDSFIQAIGTAAILETVRSGVTGIARGDKV
LSI

Sequences:

>Translated_163_residues
MRHIISLLLENEPGALSRVVGLFSQRNYNIESLTVAPTEDPTLSRLTLTTVGHDEVIEQITKNLNKLIEVVKLVDLSESA
HIERELMLVKVKATGAQRAEIKRTTDIFRGQIVDVTASVYTVQLSGTSDKLDSFIQAIGTAAILETVRSGVTGIARGDKV
LSI
>Mature_163_residues
MRHIISLLLENEPGALSRVVGLFSQRNYNIESLTVAPTEDPTLSRLTLTTVGHDEVIEQITKNLNKLIEVVKLVDLSESA
HIERELMLVKVKATGAQRAEIKRTTDIFRGQIVDVTASVYTVQLSGTSDKLDSFIQAIGTAAILETVRSGVTGIARGDKV
LSI

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=162, Percent_Identity=63.5802469135803, Blast_Score=219, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=26.9607843137255, Blast_Score=88, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 17783; Mature: 17783

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHIISLLLENEPGALSRVVGLFSQRNYNIESLTVAPTEDPTLSRLTLTTVGHDEVIEQI
CHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHH
TKNLNKLIEVVKLVDLSESAHIERELMLVKVKATGAQRAEIKRTTDIFRGQIVDVTASVY
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEEEEEEE
TVQLSGTSDKLDSFIQAIGTAAILETVRSGVTGIARGDKVLSI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
>Mature Secondary Structure
MRHIISLLLENEPGALSRVVGLFSQRNYNIESLTVAPTEDPTLSRLTLTTVGHDEVIEQI
CHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHH
TKNLNKLIEVVKLVDLSESAHIERELMLVKVKATGAQRAEIKRTTDIFRGQIVDVTASVY
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEEEEEEE
TVQLSGTSDKLDSFIQAIGTAAILETVRSGVTGIARGDKVLSI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]