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The map label for this gene is allR [H]

Identifier: 62390197

GI number: 62390197

Start: 1381019

End: 1381726

Strand: Reverse

Name: allR [H]

Synonym: cg1486

Alternate gene names: 62390197

Gene position: 1381726-1381019 (Counterclockwise)

Preceding gene: 62390200

Following gene: 62390195

Centisome position: 42.09

GC content: 61.44

Gene sequence:

>708_bases
ATGGGACAGCAAGAAATTATCGAGGACTCCACCGAGAGCGGTATTAAGGTTTTAGACCGCACTGTATTAATCCTCAATGT
CATCGCAGAACAGCCTCGATCGTTGGCAGAGCTCGCAGCTGCCACCGATCTGCCCAGGGCTACAGCCCACCGCCTCGCCT
CAGCGCTTGAGGTACACGGCATGTTGGCACGCTCCCGCGATAATAGATGGACCATCGGCGCACGGCTTGCCTCATTGGGT
GCACGCGGCGCTGACACCCTCATCGATACGGCCGTACCAATTATGGCCGACCTTATGGAGCGCACCGGCGAATCCGTTCA
GCTTTATCGCCTCACCGGCACCACCCGCACGTGTGTGGCCAGCCAAGAGCCCAGCTCCGGGCTAAAAAACGTGGTTCCCG
TGGGCACTCGCATGCCTTTAAATGCAGGGTCAGCAGCGCGCGTTTTTGCCGCCTACCTCCCCATCCCCTCTGCCAGCGTC
TTTTCCCGCGAGGAGCTTGACCAGGTGCGCGCCAGCGGCTTAGCGGAGTCCGTGGGCGAGCGTGAGCTCGGCCTTGCTAG
CCTCTCCTCCCCTGTTTTTGATTCCAACGGATCCATGATCGCGGCACTGTCCATCTCCGGCGTGGCCGAGCGCCTCAAGC
CCCACCCCGCCGCCATGTGGGGCACCGAGCTTATCGACGCCGCCGAGCGCCTAGGCGCTTTGCTTTAA

Upstream 100 bases:

>100_bases
AGAGGCATAAATGTCACCTCCCGCCCAAAATCTTTTTATACCCCCACACACAGTGAATCCCTTCACCACGTCTCATTGGG
TGAAATGCTAAATTCAAGGT

Downstream 100 bases:

>100_bases
GAGCTTTTCGACGCACAACCCCAGTTGTTTATTCAACTCATTGAACCCTAAGCGCTGGAGAGATATCTGATAAACCTCGC
TATACCACCAGATTTGCTGC

Product: IclR family regulatory protein

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MGQQEIIEDSTESGIKVLDRTVLILNVIAEQPRSLAELAAATDLPRATAHRLASALEVHGMLARSRDNRWTIGARLASLG
ARGADTLIDTAVPIMADLMERTGESVQLYRLTGTTRTCVASQEPSSGLKNVVPVGTRMPLNAGSAARVFAAYLPIPSASV
FSREELDQVRASGLAESVGERELGLASLSSPVFDSNGSMIAALSISGVAERLKPHPAAMWGTELIDAAERLGALL

Sequences:

>Translated_235_residues
MGQQEIIEDSTESGIKVLDRTVLILNVIAEQPRSLAELAAATDLPRATAHRLASALEVHGMLARSRDNRWTIGARLASLG
ARGADTLIDTAVPIMADLMERTGESVQLYRLTGTTRTCVASQEPSSGLKNVVPVGTRMPLNAGSAARVFAAYLPIPSASV
FSREELDQVRASGLAESVGERELGLASLSSPVFDSNGSMIAALSISGVAERLKPHPAAMWGTELIDAAERLGALL
>Mature_234_residues
GQQEIIEDSTESGIKVLDRTVLILNVIAEQPRSLAELAAATDLPRATAHRLASALEVHGMLARSRDNRWTIGARLASLGA
RGADTLIDTAVPIMADLMERTGESVQLYRLTGTTRTCVASQEPSSGLKNVVPVGTRMPLNAGSAARVFAAYLPIPSASVF
SREELDQVRASGLAESVGERELGLASLSSPVFDSNGSMIAALSISGVAERLKPHPAAMWGTELIDAAERLGALL

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=243, Percent_Identity=26.7489711934156, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1786715, Length=231, Percent_Identity=25.974025974026, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786468, Length=222, Percent_Identity=25.2252252252252, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 24785; Mature: 24653

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQEIIEDSTESGIKVLDRTVLILNVIAEQPRSLAELAAATDLPRATAHRLASALEVHG
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MLARSRDNRWTIGARLASLGARGADTLIDTAVPIMADLMERTGESVQLYRLTGTTRTCVA
HHHHCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEC
SQEPSSGLKNVVPVGTRMPLNAGSAARVFAAYLPIPSASVFSREELDQVRASGLAESVGE
CCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCH
RELGLASLSSPVFDSNGSMIAALSISGVAERLKPHPAAMWGTELIDAAERLGALL
HHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GQQEIIEDSTESGIKVLDRTVLILNVIAEQPRSLAELAAATDLPRATAHRLASALEVHG
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MLARSRDNRWTIGARLASLGARGADTLIDTAVPIMADLMERTGESVQLYRLTGTTRTCVA
HHHHCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEC
SQEPSSGLKNVVPVGTRMPLNAGSAARVFAAYLPIPSASVFSREELDQVRASGLAESVGE
CCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCH
RELGLASLSSPVFDSNGSMIAALSISGVAERLKPHPAAMWGTELIDAAERLGALL
HHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA