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The map label for this gene is xseA [H]

Identifier: 62389911

GI number: 62389911

Start: 1077399

End: 1078652

Strand: Reverse

Name: xseA [H]

Synonym: cg1163

Alternate gene names: 62389911

Gene position: 1078652-1077399 (Counterclockwise)

Preceding gene: 62389913

Following gene: 62389910

Centisome position: 32.86

GC content: 60.37

Gene sequence:

>1254_bases
GTGTCGTCTGAGAAAGCTTCATCAAAATCAACCCCTGAGGCACCGTGGCCAGTCCGGGAAGTAAATACTCAAGTCAAGCA
GTGGATTGAACGGCTTGGCCATTTGTGGGTGGAGGGCCAGCTCGCTCAGATTAATGTGAAGCCCAATTGGAAGCTGTCGT
ATTTGACGCTTCGTGATGTGGAGCAAGAAATGTCTGTGCAGCTGACCTGCCCGACGGACATTATCCGCAATCGCCCCACA
CCGCTCAAGGATGGCGACCGCGTGATTGTGTACGGCAAGCCCGCGTTTTATGCAGGCCGCGGCACTTTTTCGCTGTGGGT
GACTGATATCCGTCCCGTGGGTATTGGTGAGTTGCTGGCGCGCATTGAGGAGCTGCGTAAAAGGCTTGCCGCGGAGGGTC
TTTTTGATCCAGCTCGGAAGAAGCGACTGCCATTTCTGCCCAACCGCGTTGGTTTGATCACGGGACGTGGTTCAGCGGCT
GAGCGCGATGTGCTGAGCGTGGCTAAGGATCGCTGGCCGGAAGTGCAGTTTGAGGTGATCAACACGGCAGTTCAGGGCGC
TTCAGCTGTTCCTGAAATCATCGAAGCGTTGCGGGTTTTAGATCAGGACCCTCGCGTGGATGTCATCATCATTGCCCGCG
GCGGCGGTTCTGTGGAGGATCTGCTCCCCTTCTCTGAGGAGGCCTTGCAGCGCGCAGTCGCGGCAGCGCAGACGCCCGTG
GTGTCCGCGATTGGCCACGAACCAGATACGCCGGTGTTGGACAATGTCGCCGACCTTCGCGCGGCGACCCCGACCGATGC
AGCAAAGCGCGTGGTGCCTGATGTGGCAGAAGAACGCATGTTGATCAATCAGCTTCGCAGTCGTAGTGCCGCGGCGTTGC
GCGGTTGGGTGCAGCGCGAGCAGCAGGCGTTGGCAGCGATTCGCACCAGGCCGGTGCTGGCTGATCCGATGACCCCGATT
AACCGCCGACGTGATGAGATTGCCCAGGCTGTGGGCTTGATTAGGCGCGATGTCACCCATCTCGTCCGCACCGAGCAAGC
ACTGGTGGCGTCGTTGCGCGCACAGGTTTCCGCGCTCGGCCCGTCCGCAACCTTGGCGCGCGGTTATTCCGTGGTGCAGG
TTATTCCTCGCGACGGCAGCGCCCCGGAAGTGGTCACCACCATCGAGCAATCACCGCCCGGCAGCCAGCTGCGCATCCGC
GTTGCCGACGGCTCCATCACTGCGGCATCCATGGGCACCCAGCAAGCAAACTAA

Upstream 100 bases:

>100_bases
TCCAACGTTGAGGCTAAACACCTAGACTGGGAATGCAACCACCCCGACAAAGGCGGGGTAATTCACTTTTAGCTGGTGGA
AGAAGGAGAATCACACGCCT

Downstream 100 bases:

>100_bases
AAACTTAGGAGAATGAAGAAATGACCAATCCAGATATCGTCGGTTCCGGCCAAGGCAACGATTCCTTCGAGCCAGTCGCC
CAATTATCCTACGAGCGTGC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDVEQEMSVQLTCPTDIIRNRPT
PLKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLARIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAA
ERDVLSVAKDRWPEVQFEVINTAVQGASAVPEIIEALRVLDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPV
VSAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQREQQALAAIRTRPVLADPMTPI
NRRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALGPSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIR
VADGSITAASMGTQQAN

Sequences:

>Translated_417_residues
MSSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDVEQEMSVQLTCPTDIIRNRPT
PLKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLARIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAA
ERDVLSVAKDRWPEVQFEVINTAVQGASAVPEIIEALRVLDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPV
VSAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQREQQALAAIRTRPVLADPMTPI
NRRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALGPSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIR
VADGSITAASMGTQQAN
>Mature_416_residues
SSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDVEQEMSVQLTCPTDIIRNRPTP
LKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLARIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAAE
RDVLSVAKDRWPEVQFEVINTAVQGASAVPEIIEALRVLDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPVV
SAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQREQQALAAIRTRPVLADPMTPIN
RRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALGPSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIRV
ADGSITAASMGTQQAN

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=441, Percent_Identity=31.2925170068027, Blast_Score=175, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45583; Mature: 45452

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCEEEEEEECCCCEEEEEEHHHH
EQEMSVQLTCPTDIIRNRPTPLKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLA
HHHCCEEEECCHHHHCCCCCCCCCCCEEEEEECCEEEECCCEEEEEEECCCCCCHHHHHH
RIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAAERDVLSVAKDRWPEVQFEVI
HHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHH
NTAVQGASAVPEIIEALRVLDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPV
HHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHCCH
VSAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQRE
HHHHCCCCCCCHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQALAAIRTRPVLADPMTPINRRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIRVADGSITAASMGTQQAN
CCHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCEEEHHCCCCCCC
>Mature Secondary Structure 
SSEKASSKSTPEAPWPVREVNTQVKQWIERLGHLWVEGQLAQINVKPNWKLSYLTLRDV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCEEEEEEECCCCEEEEEEHHHH
EQEMSVQLTCPTDIIRNRPTPLKDGDRVIVYGKPAFYAGRGTFSLWVTDIRPVGIGELLA
HHHCCEEEECCHHHHCCCCCCCCCCCEEEEEECCEEEECCCEEEEEEECCCCCCHHHHHH
RIEELRKRLAAEGLFDPARKKRLPFLPNRVGLITGRGSAAERDVLSVAKDRWPEVQFEVI
HHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHH
NTAVQGASAVPEIIEALRVLDQDPRVDVIIIARGGGSVEDLLPFSEEALQRAVAAAQTPV
HHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHCCH
VSAIGHEPDTPVLDNVADLRAATPTDAAKRVVPDVAEERMLINQLRSRSAAALRGWVQRE
HHHHCCCCCCCHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQALAAIRTRPVLADPMTPINRRRDEIAQAVGLIRRDVTHLVRTEQALVASLRAQVSALG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSATLARGYSVVQVIPRDGSAPEVVTTIEQSPPGSQLRIRVADGSITAASMGTQQAN
CCHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA