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The map label for this gene is cyaB

Identifier: 62389209

GI number: 62389209

Start: 326693

End: 328336

Strand: Reverse

Name: cyaB

Synonym: cg0375

Alternate gene names: NA

Gene position: 328336-326693 (Counterclockwise)

Preceding gene: 62389222

Following gene: 62389206

Centisome position: 10.0

GC content: 57.48

Gene sequence:

>1644_bases
TTGGACACTGTTTTGGAGCCGGCGAGACTGTCAAACACACTCGAATTAGTCACGATCTCTACACTACTTCCTCACTACAT
CCTCGCGATGTCGCACCGGCACGTTAGAGTATTGAGCATGAGTCGATTGCTTAGAGCATTGAAATGGCTGTGGGGCACAT
CGTGGCCGCTGTATGCTGCGACGGTGCTCGGCACGAATGTGTTTGGTGCGCTCGCAGTAATGCTGTTTGTGCGCTTCCTC
ATTCCGCAGCCAGATGCTTCAAATTTCAACGCTGAGATCTCGTATCTGCCAGCTGTTGGTTTCGCATACCTGGCGTTCGC
CATTGTCGCGGGCATGCTGGTGACATTTTTGATGTTCCGCCCGGTGCTTGATTGGCAGCGAAGCCCTGAAGATCATGACC
GAAATATGGTGCGCAACTTGGTTATGCGCATCCCCATCTACCAGGCAATTCTGTGCGCAGTGGTGTGGTTAATCGGCATT
GCAATTGCAACGTTGATTTCGGCCAGTGTGTCTACCAGTTTGGCGCTGGTCGTGGCGTTTTCCACGTTGATGGCTGCCGC
AATCGTCGTGCTGCTCACCTACCTTGAGGCTGAGCGTTTGGTGCGTCCGGTTGCTGCGTCTGCCCTGGCGCGTCGATTTG
AGGATTCCACGCTGGAACCACCTGTGAGCCAGCGCTTGCGTATGACGTGGTTGCTGACGTTGGGCATTCCAGTGATGGGA
ATTCTGCTGCTTATTTGGGGCTACTCGCAGGGCATTTTCGGCTCTGATGCCTCCGGAATTATGCCTGCCATCGCAGCGCT
CGCGTTTGCATCGTTGGTCACGGGTTACCTGGGCAACCGGCTTGTGGTGTCCTCTGTGGTGGATCCGATTCGGGAACTTC
AGGAGGCCATCAACAGGGTTCGTCGTGGTGAAAACGATGTGCAGGTTGATATTTATGATGGCTCTGAGATCGGTGTGCTT
CAGGCTGGCTTCAATGAGATGATGCGTGGCCTGCGTGAACGTCAGCGCGTCCGTGACCTTTTCGGTCGCTACGTGGGCGC
TGAAGTGGCCAAGCGTGCGCTGGAGGAACGCCCCACTCTGGGTGGCGAGGACCGTAAGGTTGCCGTGTTGTTTGTCGATG
TCATCGGCTCCACTACCTTTGCCGTCAACCACACTCCTGAAGAGGTTGTGGAGGCGCTCAATGAGTTCTTCGAGCACGTC
GTGGAGGTTGTGCACCGCAACAAGGGTGTTATCAACAAGTTCCAGGGTGACGCGGCGTTGGCGATTTTCGGCGCTCCCCT
GCCCCTGTCTGATGCCACCGGTCATGCGCTTGCGGCTGCCCGTGAGCTCCGCGCAGAGCTGAAAGATCTCCAGCTCAAGG
CCGGAATTGGTGTGGCTGCTGGCCATGTCGTTGCTGGTCATATCGGCGGTCACGCGAGGTTTGAGTACACTGTGATCGGC
GACGCGGTGAACCAGGCTGCGCGCCTGACGGAGATCGCGAAAACGACCCCAGGCCGCACCGTCACCAACGCTTCCACGCT
GCGTGAGGCCAACGAGGCGGAGCAGGCTCGCTGGACGCTCATGAAGTCCGTGGAGCTGCGCGGACGTAGCCAGATGACGC
AGATTGCGCGGCCTATTCGGCCGACGTTGGCGGATAGGTCCTAA

Upstream 100 bases:

>100_bases
GATCATTGCAGGGTTTTGGTGTTCTGCCCGGGCGCGGGCACGTTCTGTGGTTCGGGCGCGGACAAGGGCACGCGCGCTGG
AGGCCGCGTCGAAAAGCGTC

Downstream 100 bases:

>100_bases
TACGCTTTTCGACGCAAAAATCCCCCGTTTCACACTGTGAGACGGGGGATTTTTCTCTTGGCAACACCAATGAGCTAGTC
CGAAAACAACCCATCTACTA

Product: adenylate cyclase

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MDTVLEPARLSNTLELVTISTLLPHYILAMSHRHVRVLSMSRLLRALKWLWGTSWPLYAATVLGTNVFGALAVMLFVRFL
IPQPDASNFNAEISYLPAVGFAYLAFAIVAGMLVTFLMFRPVLDWQRSPEDHDRNMVRNLVMRIPIYQAILCAVVWLIGI
AIATLISASVSTSLALVVAFSTLMAAAIVVLLTYLEAERLVRPVAASALARRFEDSTLEPPVSQRLRMTWLLTLGIPVMG
ILLLIWGYSQGIFGSDASGIMPAIAALAFASLVTGYLGNRLVVSSVVDPIRELQEAINRVRRGENDVQVDIYDGSEIGVL
QAGFNEMMRGLRERQRVRDLFGRYVGAEVAKRALEERPTLGGEDRKVAVLFVDVIGSTTFAVNHTPEEVVEALNEFFEHV
VEVVHRNKGVINKFQGDAALAIFGAPLPLSDATGHALAAARELRAELKDLQLKAGIGVAAGHVVAGHIGGHARFEYTVIG
DAVNQAARLTEIAKTTPGRTVTNASTLREANEAEQARWTLMKSVELRGRSQMTQIARPIRPTLADRS

Sequences:

>Translated_547_residues
MDTVLEPARLSNTLELVTISTLLPHYILAMSHRHVRVLSMSRLLRALKWLWGTSWPLYAATVLGTNVFGALAVMLFVRFL
IPQPDASNFNAEISYLPAVGFAYLAFAIVAGMLVTFLMFRPVLDWQRSPEDHDRNMVRNLVMRIPIYQAILCAVVWLIGI
AIATLISASVSTSLALVVAFSTLMAAAIVVLLTYLEAERLVRPVAASALARRFEDSTLEPPVSQRLRMTWLLTLGIPVMG
ILLLIWGYSQGIFGSDASGIMPAIAALAFASLVTGYLGNRLVVSSVVDPIRELQEAINRVRRGENDVQVDIYDGSEIGVL
QAGFNEMMRGLRERQRVRDLFGRYVGAEVAKRALEERPTLGGEDRKVAVLFVDVIGSTTFAVNHTPEEVVEALNEFFEHV
VEVVHRNKGVINKFQGDAALAIFGAPLPLSDATGHALAAARELRAELKDLQLKAGIGVAAGHVVAGHIGGHARFEYTVIG
DAVNQAARLTEIAKTTPGRTVTNASTLREANEAEQARWTLMKSVELRGRSQMTQIARPIRPTLADRS
>Mature_547_residues
MDTVLEPARLSNTLELVTISTLLPHYILAMSHRHVRVLSMSRLLRALKWLWGTSWPLYAATVLGTNVFGALAVMLFVRFL
IPQPDASNFNAEISYLPAVGFAYLAFAIVAGMLVTFLMFRPVLDWQRSPEDHDRNMVRNLVMRIPIYQAILCAVVWLIGI
AIATLISASVSTSLALVVAFSTLMAAAIVVLLTYLEAERLVRPVAASALARRFEDSTLEPPVSQRLRMTWLLTLGIPVMG
ILLLIWGYSQGIFGSDASGIMPAIAALAFASLVTGYLGNRLVVSSVVDPIRELQEAINRVRRGENDVQVDIYDGSEIGVL
QAGFNEMMRGLRERQRVRDLFGRYVGAEVAKRALEERPTLGGEDRKVAVLFVDVIGSTTFAVNHTPEEVVEALNEFFEHV
VEVVHRNKGVINKFQGDAALAIFGAPLPLSDATGHALAAARELRAELKDLQLKAGIGVAAGHVVAGHIGGHARFEYTVIG
DAVNQAARLTEIAKTTPGRTVTNASTLREANEAEQARWTLMKSVELRGRSQMTQIARPIRPTLADRS

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: 4.6.1.1

Molecular weight: Translated: 59893; Mature: 59893

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTVLEPARLSNTLELVTISTLLPHYILAMSHRHVRVLSMSRLLRALKWLWGTSWPLYAA
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
TVLGTNVFGALAVMLFVRFLIPQPDASNFNAEISYLPAVGFAYLAFAIVAGMLVTFLMFR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
PVLDWQRSPEDHDRNMVRNLVMRIPIYQAILCAVVWLIGIAIATLISASVSTSLALVVAF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLMAAAIVVLLTYLEAERLVRPVAASALARRFEDSTLEPPVSQRLRMTWLLTLGIPVMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILLLIWGYSQGIFGSDASGIMPAIAALAFASLVTGYLGNRLVVSSVVDPIRELQEAINRV
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RRGENDVQVDIYDGSEIGVLQAGFNEMMRGLRERQRVRDLFGRYVGAEVAKRALEERPTL
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GGEDRKVAVLFVDVIGSTTFAVNHTPEEVVEALNEFFEHVVEVVHRNKGVINKFQGDAAL
CCCCCEEEEEEEEHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
AIFGAPLPLSDATGHALAAARELRAELKDLQLKAGIGVAAGHVVAGHIGGHARFEYTVIG
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHEECCCCCCEEEEEEEC
DAVNQAARLTEIAKTTPGRTVTNASTLREANEAEQARWTLMKSVELRGRSQMTQIARPIR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
PTLADRS
CCCCCCC
>Mature Secondary Structure
MDTVLEPARLSNTLELVTISTLLPHYILAMSHRHVRVLSMSRLLRALKWLWGTSWPLYAA
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
TVLGTNVFGALAVMLFVRFLIPQPDASNFNAEISYLPAVGFAYLAFAIVAGMLVTFLMFR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
PVLDWQRSPEDHDRNMVRNLVMRIPIYQAILCAVVWLIGIAIATLISASVSTSLALVVAF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLMAAAIVVLLTYLEAERLVRPVAASALARRFEDSTLEPPVSQRLRMTWLLTLGIPVMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILLLIWGYSQGIFGSDASGIMPAIAALAFASLVTGYLGNRLVVSSVVDPIRELQEAINRV
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RRGENDVQVDIYDGSEIGVLQAGFNEMMRGLRERQRVRDLFGRYVGAEVAKRALEERPTL
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GGEDRKVAVLFVDVIGSTTFAVNHTPEEVVEALNEFFEHVVEVVHRNKGVINKFQGDAAL
CCCCCEEEEEEEEHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
AIFGAPLPLSDATGHALAAARELRAELKDLQLKAGIGVAAGHVVAGHIGGHARFEYTVIG
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHEECCCCCCEEEEEEEC
DAVNQAARLTEIAKTTPGRTVTNASTLREANEAEQARWTLMKSVELRGRSQMTQIARPIR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
PTLADRS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]