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The map label for this gene is qor [H]

Identifier: 62389100

GI number: 62389100

Start: 220152

End: 221108

Strand: Reverse

Name: qor [H]

Synonym: cg0251

Alternate gene names: 62389100

Gene position: 221108-220152 (Counterclockwise)

Preceding gene: 62389101

Following gene: 62389098

Centisome position: 6.74

GC content: 55.17

Gene sequence:

>957_bases
ATGCAAGCCATCGTCCAAACTGAGGAGAAGGTCACTGCTTCTCTGGAATTACAGGAAGTCCCCGTCCCGACCCTGAAGCC
AGGTGAGGTGCTGGTGGAGGTGAAGGCTGCGGGCGTTAACCGTGCGGATCTTTTGCAGACGCAGGGAAATTATCCTGTGC
CGGCGGGGGCTTCGGAGATTCTCGGGCTGGAATGTGCGGGTGTGATCGTGGATGCCGGCGACACTGGGCAAACAGTGGGT
CAGGAAGTCGCTTGCCTTCTCACTGGCGGTGGATATGCGCAATATGTGGCGGTTCCGGAAGGTCAGTTGATGCCAATTCC
AGAGGGTTACAGCTTTGTGGAAGCGGCCTCGATCGTGGAGGTTGCGTGCACGGTGTGGTCGAATATCGGCATGCTGGCGG
GCTTGCAGAAGGAGGATACTTTCCTTATTCATGGTGGCGCGGGCGGTATCGGAACGTTTGCCATTCAGATGGGCAAGGCT
CTGGGTGTGACGGTTGCGGTGACTGCCGGTTCAACTGAAAAGTTAAAAACCTGTAAGAACTTAGGGGCCGATATCCTCAT
CAATTACAAGGAGGAAGATTTCGCCGAGGTTTTGAAGAACAAGGCGGATGTCATTCTCGATATTATTGGTGCGAAGTATT
TGTCACAGAATGTGAAGGCGATGGCCAAGGACGCGCACATGGTAGTCATCGGGATGCAGGGTGGCGTGAAAGGGGAGCTG
AATTTGGGTCATCTTTTGGCCAAGCGAGGCACGATTTCTGCCACTGCGCTGCGTGGTCGCGATGAGGCGGATAAGGCTCG
GATTGTCAGCAGCACTGTCGAAAATATTTGGCCGCTGCTGCAATCGAAGGAAATTACCCCTCACATCGACCACACCTTGC
CGCTAGCCGAAGCAGCCGCCGCCTTGCAGAAAATTCAAGACGGCACCATCACCGGCAAGCTCGTGCTTGCGGTTTAG

Upstream 100 bases:

>100_bases
GTGCGGGGCTAAATGTGGTGGCAACTCTGACGTCAATCGGCGCAACGATCTGGAATAACCGGCTACCCTCGAATGCATGA
CTAAAACCACGCGCCAAACC

Downstream 100 bases:

>100_bases
GCAAGCGATGCCAGCACCCTGGTCAGCTGATCCACTTCATAGTAGGTGCTAAACGGGCTTAGTCCGATAGTGATCGATCC
GCCAGCTTCAGTCACACCCA

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MQAIVQTEEKVTASLELQEVPVPTLKPGEVLVEVKAAGVNRADLLQTQGNYPVPAGASEILGLECAGVIVDAGDTGQTVG
QEVACLLTGGGYAQYVAVPEGQLMPIPEGYSFVEAASIVEVACTVWSNIGMLAGLQKEDTFLIHGGAGGIGTFAIQMGKA
LGVTVAVTAGSTEKLKTCKNLGADILINYKEEDFAEVLKNKADVILDIIGAKYLSQNVKAMAKDAHMVVIGMQGGVKGEL
NLGHLLAKRGTISATALRGRDEADKARIVSSTVENIWPLLQSKEITPHIDHTLPLAEAAAALQKIQDGTITGKLVLAV

Sequences:

>Translated_318_residues
MQAIVQTEEKVTASLELQEVPVPTLKPGEVLVEVKAAGVNRADLLQTQGNYPVPAGASEILGLECAGVIVDAGDTGQTVG
QEVACLLTGGGYAQYVAVPEGQLMPIPEGYSFVEAASIVEVACTVWSNIGMLAGLQKEDTFLIHGGAGGIGTFAIQMGKA
LGVTVAVTAGSTEKLKTCKNLGADILINYKEEDFAEVLKNKADVILDIIGAKYLSQNVKAMAKDAHMVVIGMQGGVKGEL
NLGHLLAKRGTISATALRGRDEADKARIVSSTVENIWPLLQSKEITPHIDHTLPLAEAAAALQKIQDGTITGKLVLAV
>Mature_318_residues
MQAIVQTEEKVTASLELQEVPVPTLKPGEVLVEVKAAGVNRADLLQTQGNYPVPAGASEILGLECAGVIVDAGDTGQTVG
QEVACLLTGGGYAQYVAVPEGQLMPIPEGYSFVEAASIVEVACTVWSNIGMLAGLQKEDTFLIHGGAGGIGTFAIQMGKA
LGVTVAVTAGSTEKLKTCKNLGADILINYKEEDFAEVLKNKADVILDIIGAKYLSQNVKAMAKDAHMVVIGMQGGVKGEL
NLGHLLAKRGTISATALRGRDEADKARIVSSTVENIWPLLQSKEITPHIDHTLPLAEAAAALQKIQDGTITGKLVLAV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=317, Percent_Identity=40.3785488958991, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI22538444, Length=317, Percent_Identity=40.3785488958991, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI28557745, Length=271, Percent_Identity=31.3653136531365, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=26.517571884984, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI194239674, Length=310, Percent_Identity=26.4516129032258, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI13236495, Length=310, Percent_Identity=26.4516129032258, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI24308257, Length=328, Percent_Identity=25.609756097561, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI47519420, Length=336, Percent_Identity=26.4880952380952, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI194239676, Length=305, Percent_Identity=25.5737704918033, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790485, Length=249, Percent_Identity=30.1204819277108, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17507255, Length=325, Percent_Identity=26.4615384615385, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71987554, Length=350, Percent_Identity=27.7142857142857, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=317, Percent_Identity=28.391167192429, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=301, Percent_Identity=25.2491694352159, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=205, Percent_Identity=30.2439024390244, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=288, Percent_Identity=25.3472222222222, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=221, Percent_Identity=30.316742081448, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581339, Length=350, Percent_Identity=26, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24581341, Length=344, Percent_Identity=26.7441860465116, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33177; Mature: 33177

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIVQTEEKVTASLELQEVPVPTLKPGEVLVEVKAAGVNRADLLQTQGNYPVPAGASEI
CCCHHCCHHHHEEEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCHHHH
LGLECAGVIVDAGDTGQTVGQEVACLLTGGGYAQYVAVPEGQLMPIPEGYSFVEAASIVE
HCEEEEEEEEECCCCCCHHHHEEEEEEECCCEEEEEECCCCCEEECCCCCCHHHHHHHHH
VACTVWSNIGMLAGLQKEDTFLIHGGAGGIGTFAIQMGKALGVTVAVTAGSTEKLKTCKN
HHHHHHHCCHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
LGADILINYKEEDFAEVLKNKADVILDIIGAKYLSQNVKAMAKDAHMVVIGMQGGVKGEL
CCCEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
NLGHLLAKRGTISATALRGRDEADKARIVSSTVENIWPLLQSKEITPHIDHTLPLAEAAA
CHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALQKIQDGTITGKLVLAV
HHHHHCCCCEEEEEEEEC
>Mature Secondary Structure
MQAIVQTEEKVTASLELQEVPVPTLKPGEVLVEVKAAGVNRADLLQTQGNYPVPAGASEI
CCCHHCCHHHHEEEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCHHHH
LGLECAGVIVDAGDTGQTVGQEVACLLTGGGYAQYVAVPEGQLMPIPEGYSFVEAASIVE
HCEEEEEEEEECCCCCCHHHHEEEEEEECCCEEEEEECCCCCEEECCCCCCHHHHHHHHH
VACTVWSNIGMLAGLQKEDTFLIHGGAGGIGTFAIQMGKALGVTVAVTAGSTEKLKTCKN
HHHHHHHCCHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
LGADILINYKEEDFAEVLKNKADVILDIIGAKYLSQNVKAMAKDAHMVVIGMQGGVKGEL
CCCEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
NLGHLLAKRGTISATALRGRDEADKARIVSSTVENIWPLLQSKEITPHIDHTLPLAEAAA
CHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALQKIQDGTITGKLVLAV
HHHHHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]