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The map label for this gene is ntdC [H]

Identifier: 62389065

GI number: 62389065

Start: 182820

End: 184055

Strand: Direct

Name: ntdC [H]

Synonym: cg0211

Alternate gene names: 62389065

Gene position: 182820-184055 (Clockwise)

Preceding gene: 62389063

Following gene: 62389066

Centisome position: 5.57

GC content: 57.69

Gene sequence:

>1236_bases
GTGACTCAGCAAGAACTTCGCGTAGCTGTCATTGGTGCAGGCATGGCAGGCAAAGCACACGCAGCGGGCTACCGCACCGC
ATCCAGCATCTACTCCACCACTCTGCCCAACATCCGTTTGGTTTCCATCGCGGATGCCAACGTGCAGCTAGCTGAAGAAA
CCGCAGCACGCTTTGGCTTTGAGCGCTTTGATACCTCTTGGCAGGCGATCGTTGAGGCCGATGACATCGATGTTGTCAGC
GTCGTGGTGGCTAACTTCCTGCACCGCGAAATCGTGGAAGCACTTCTGGCATCCGGCAAGCATGTGCTGTGCGAGAAGCC
ACTGTCAGACACCATCGAAGATGCAGAAGCCATGATTGAGGCAGCCGGCCGTGCAGCAACAAATGGCACCATCGCCCGCA
TCGGACTGACCTACCGCCGTTCCCCAGGCGTGGCACACATCCGTGATCTCGTGCAGTCCGGCGAGCTTGGCAAGGTTCTA
CACGTCACCGGCCACTACTGGACCGACTACGGATCCAATGCACAGGCACCAATCAGCTGGCGTTACAAGGGGCCAAACGG
CTCCGGCGCACTGGCAGATGTGGGAAGCCACCTCACCTACCTGGCAGAATTCGTTGCAGGATCTGACTTCGCCGCCGTCC
GTGGTGGCCAGTTGTCCACCGTGATCACCGAGCGCCCCAAGCCACTCGGCGCGATTGTCGGCCACGAAGGCGGCGCAGTT
TCCGATGAATACGAAGCAGTGGAAAATGATGACATTGCATCATTCTCCGGATCCTTCATCGGTGGCGGAACCGCAACCCT
CCAGGTCAGCCGCATTTCCCAGGGACACCCAAACACCCTAGGTTTTGAAGTGTTCTGTGAAAAGGGCTCCGTGCTCTTTG
ATTTCCGCAACTCAGGCGAATTCAAAATCTTCACCCCAGCAACCTCCGGTGACATCAGCCAAGAAGCCGGCTACCGCACC
ATCACCATCGGACCAAAGCACCCATACTGGCGCGGCGGCCTTGCAATGGATGCACCAGGCGTGGGAATTGGCCAAAACGA
AGGCTTCGTTTTCCAGGCGCGCGCATTCCTCGAAGAAATCGCAGGAATCTCCGAAGCTGAAAGCCTGCCACGCTGCGCAA
CTTTGGAAGAAGGGCTACACAATATGCAGCTCATTGATGCTGTATCACAGTCAGCTGCAGCAGGTGGCGAAACCGTTGCG
GTCCCAGCGGCTGCTCTGATCCCTGCAAACAACTAG

Upstream 100 bases:

>100_bases
AACAAATATAGCTTGTGTTGGAGCGCTCCAATTGCGTAGTGGATCACAATACCGGATCCACATGGTCTAACAACACATCA
TCTTTTTCGAGGAGGTCATA

Downstream 100 bases:

>100_bases
AAACTATTCAGAAAGCATCACCATGAAACTCGGTCTCTACAACGCGATCTTCCACGACCGCACCCTGCCAGAAGCGCTCG
CAGCCATCAAAGCTGCAGGT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGFERFDTSWQAIVEADDIDVVS
VVVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIEAAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVL
HVTGHYWTDYGSNAQAPISWRYKGPNGSGALADVGSHLTYLAEFVAGSDFAAVRGGQLSTVITERPKPLGAIVGHEGGAV
SDEYEAVENDDIASFSGSFIGGGTATLQVSRISQGHPNTLGFEVFCEKGSVLFDFRNSGEFKIFTPATSGDISQEAGYRT
ITIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEIAGISEAESLPRCATLEEGLHNMQLIDAVSQSAAAGGETVA
VPAAALIPANN

Sequences:

>Translated_411_residues
MTQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGFERFDTSWQAIVEADDIDVVS
VVVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIEAAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVL
HVTGHYWTDYGSNAQAPISWRYKGPNGSGALADVGSHLTYLAEFVAGSDFAAVRGGQLSTVITERPKPLGAIVGHEGGAV
SDEYEAVENDDIASFSGSFIGGGTATLQVSRISQGHPNTLGFEVFCEKGSVLFDFRNSGEFKIFTPATSGDISQEAGYRT
ITIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEIAGISEAESLPRCATLEEGLHNMQLIDAVSQSAAAGGETVA
VPAAALIPANN
>Mature_410_residues
TQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGFERFDTSWQAIVEADDIDVVSV
VVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIEAAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVLH
VTGHYWTDYGSNAQAPISWRYKGPNGSGALADVGSHLTYLAEFVAGSDFAAVRGGQLSTVITERPKPLGAIVGHEGGAVS
DEYEAVENDDIASFSGSFIGGGTATLQVSRISQGHPNTLGFEVFCEKGSVLFDFRNSGEFKIFTPATSGDISQEAGYRTI
TIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEIAGISEAESLPRCATLEEGLHNMQLIDAVSQSAAAGGETVAV
PAAALIPANN

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=215, Percent_Identity=31.6279069767442, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082405, Length=206, Percent_Identity=26.2135922330097, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581117, Length=136, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 43268; Mature: 43137

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGF
CCHHHEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHHCH
ERFDTSWQAIVEADDIDVVSVVVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIE
HHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
AAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVLHVTGHYWTDYGSNAQAPISW
HHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCCCEEE
RYKGPNGSGALADVGSHLTYLAEFVAGSDFAAVRGGQLSTVITERPKPLGAIVGHEGGAV
EEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCEEEEECCCCCC
SDEYEAVENDDIASFSGSFIGGGTATLQVSRISQGHPNTLGFEVFCEKGSVLFDFRNSGE
CCHHHHCCCCCCHHCCCCEECCCEEEEEEEECCCCCCCCCCEEEEECCCCEEEEECCCCC
FKIFTPATSGDISQEAGYRTITIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEI
EEEECCCCCCCCHHHCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEHHHHHHHHH
AGISEAESLPRCATLEEGLHNMQLIDAVSQSAAAGGETVAVPAAALIPANN
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECEEEEECCCC
>Mature Secondary Structure 
TQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGF
CHHHEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHHCH
ERFDTSWQAIVEADDIDVVSVVVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIE
HHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
AAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVLHVTGHYWTDYGSNAQAPISW
HHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCCCEEE
RYKGPNGSGALADVGSHLTYLAEFVAGSDFAAVRGGQLSTVITERPKPLGAIVGHEGGAV
EEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCEEEEECCCCCC
SDEYEAVENDDIASFSGSFIGGGTATLQVSRISQGHPNTLGFEVFCEKGSVLFDFRNSGE
CCHHHHCCCCCCHHCCCCEECCCEEEEEEEECCCCCCCCCCEEEEECCCCEEEEECCCCC
FKIFTPATSGDISQEAGYRTITIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEI
EEEECCCCCCCCHHHCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEHHHHHHHHH
AGISEAESLPRCATLEEGLHNMQLIDAVSQSAAAGGETVAVPAAALIPANN
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]