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The map label for this gene is iolC [H]

Identifier: 62389052

GI number: 62389052

Start: 168976

End: 169995

Strand: Direct

Name: iolC [H]

Synonym: cg0197

Alternate gene names: 62389052

Gene position: 168976-169995 (Clockwise)

Preceding gene: 62389050

Following gene: 62389053

Centisome position: 5.15

GC content: 55.88

Gene sequence:

>1020_bases
ATGACATGCGATCGTGAGGGTCGCCACATTCCATCAAAAATGAGTGAAGGGTTGCATCGCCACATGACTAACTTGACGAG
CACTCACGAAGTCCTAGCTATCGGCCGCTTGGGCGTAGATATTTACCCACTTCAAAGTGGAGTAGGACTGGCCGATGTTC
AATCTTTCGGCAAGTACCTCGGCGGAAGCGCAGCAAACGTTTCTGTTGCAGCCGCCCGCCATGGACACAATTCCGCACTG
CTGTCCCGTGTGGGAAATGATCCTTTCGGCGAGTACCTGCTTGCTGAGCTGGAGCGTTTGGGCGTGGACAACCAGTACGT
TGCCACCGATCAGACTTTTAAGACCCCAGTGACCTTCTGTGAAATTTTCCCACCGGATGATTTCCCACTGTACTTCTACC
GCGAACCAAAGGCTCCGGATCTCAATATTGAATCCGCAGACGTCAGCCTGGACGATGTGCGCGAAGCCGATATTTTGTGG
TTCACACTCACTGGTTTCAGTGAAGAGCCAAGCCGCGGCACACACCGCGAGATCTTGACTACTCGTGCGAACCGTCGCCA
CACCATCTTTGATCTGGACTACCGACCAATGTTCTGGGAATCCCCAGAAGAGGCCACCAAGCAGGCGGAATGGGCGTTGC
AGCATTCCACGGTGGCGGTTGGCAACAAGGAAGAATGCGAAATCGCAGTGGGCGAGACCGAGCCAGAGCGCGCGGGCCGA
GCACTGTTGGAACGCGGTGTGGAGTTGGCCATCGTCAAGCAGGGACCTAAGGGTGTCATGGCGATGACCAAGGACGAAAC
CGTAGAAGTTCCTCCGTTCTTCGTCGATGTCATCAACGGTCTTGGTGCCGGCGATGCATTCGGCGGCGCGCTGTGCCACG
GTCTGCTCTCTGAATGGCCGTTGGAAAAGGTTCTCCGTTTTGCCAACACCGCGGGTGCGCTTGTGGCGTCCCGTCTTGAA
TGCTCCACCGCAATGCCTACTACCGATGAGGTGGAAGCCTCCCTCAACCAGAAAGTCTGA

Upstream 100 bases:

>100_bases
TGAAAACCGGGGCGTTGCCCTGGGGTTTTGCGCGTTTTCGGGAATCGTTTTAGAAAATTTTCGGAAATGTATTGCTTTGT
CAGGACAATGTGTTATTGTC

Downstream 100 bases:

>100_bases
TATGACTCCTCCGATTATCTCCCCAGAGAGCTTTGAAGCCCTAAGGCGGATGCGTGCGGCTGAACCCACGATGGTGGCGG
AACGTTTCAAGCAGCGCCGT

Product: ribokinase family sugar kinase

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTCDREGRHIPSKMSEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYLGGSAANVSVAAARHGHNSAL
LSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPDLNIESADVSLDDVREADILW
FTLTGFSEEPSRGTHREILTTRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGR
ALLERGVELAIVKQGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGALVASRLE
CSTAMPTTDEVEASLNQKV

Sequences:

>Translated_339_residues
MTCDREGRHIPSKMSEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYLGGSAANVSVAAARHGHNSAL
LSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPDLNIESADVSLDDVREADILW
FTLTGFSEEPSRGTHREILTTRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGR
ALLERGVELAIVKQGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGALVASRLE
CSTAMPTTDEVEASLNQKV
>Mature_338_residues
TCDREGRHIPSKMSEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYLGGSAANVSVAAARHGHNSALL
SRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPDLNIESADVSLDDVREADILWF
TLTGFSEEPSRGTHREILTTRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGRA
LLERGVELAIVKQGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGALVASRLEC
STAMPTTDEVEASLNQKV

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=324, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790193, Length=284, Percent_Identity=26.4084507042254, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 37207; Mature: 37076

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCDREGRHIPSKMSEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYL
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHEEECCCCCEEEECCCCCCHHHHHHHHHHH
GGSAANVSVAAARHGHNSALLSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFC
CCCCCCEEEEEHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEE
EIFPPDDFPLYFYREPKAPDLNIESADVSLDDVREADILWFTLTGFSEEPSRGTHREILT
EECCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHH
TRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGR
HCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCEEECCCCCCCEEEECCCCHHHHHH
ALLERGVELAIVKQGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWP
HHHHCCCEEEEEECCCCCCEEECCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
LEKVLRFANTAGALVASRLECSTAMPTTDEVEASLNQKV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
TCDREGRHIPSKMSEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYL
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHEEECCCCCEEEECCCCCCHHHHHHHHHHH
GGSAANVSVAAARHGHNSALLSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFC
CCCCCCEEEEEHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEE
EIFPPDDFPLYFYREPKAPDLNIESADVSLDDVREADILWFTLTGFSEEPSRGTHREILT
EECCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHH
TRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGR
HCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCEEECCCCCCCEEEECCCCHHHHHH
ALLERGVELAIVKQGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWP
HHHHCCCEEEEEECCCCCCEEECCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
LEKVLRFANTAGALVASRLECSTAMPTTDEVEASLNQKV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA