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The map label for this gene is gapA [H]

Identifier: 59711520

GI number: 59711520

Start: 1007490

End: 1008485

Strand: Reverse

Name: gapA [H]

Synonym: VF_0913

Alternate gene names: 59711520

Gene position: 1008485-1007490 (Counterclockwise)

Preceding gene: 59711522

Following gene: 59711519

Centisome position: 34.8

GC content: 43.47

Gene sequence:

>996_bases
ATGACTATCAAAGTAGGTATTAACGGTTTTGGCCGTATTGGACGTTTCGTATTCCGTGCATCTGTAGAGCGCAATGACAT
CGAAGTTGTTGGTATTAACGATCTTATCGACGTTGAATACATGGCTTACATGCTTAAGTACGATTCAACTCACGGCCGTT
TCAACGGTACAGTTGAAGTTGTAGATGGTAACCTAGTAGTAAACGGCAAAACTGTACGTGTAACTGCTGAGCGTAACCCA
GAAGATCGTAAGTGGGATGCAATCAACGTTGACGTTGTTGCTGAAGCAACTGGTCTATTCCTAGACGACGCAACTGCACG
TAAGCACATCACTGCTGGTGCTAAGAAAGTTGTTCTAACTGGTCCTTCAAAAGACGCTACTCCAATGTTCGTAATGGGTG
TTAACCACGAATCTTACGCTGGTCAAGACATCGTTTCTAACGCTTCTTGTACTACTAACTGTCTAGCACCTGTTGCTAAA
GTTCTTAACGACAAGTTCGGTATCGAATCTGGTCTTATGACTACAGTTCACGCTACTACAGCAACTCAAAAAACTGTAGA
TGGTCCTTCTGCTAAAGACTGGCGCGGTGGCCGTGGTGCTTCTCAAAACATCATCCCATCTTCAACTGGTGCTGCTAAAG
CTGTAGGCGTTGTTCTTCCAGAACTAAACGGCCTTCTAACTGGTATGGCTTTCCGTGTACCAACTGCTAACGTTTCTGTA
GTTGACCTAACAGTTAACCTAAAAACTGCTGCATCTTACGAAGCAATCTGTGCTGCTATGAAAGAAGCATCTGAAGGCGA
GCTTAAAGGTGTTCTAGGTTACACAGAAGACGCTGTTGTTTCTCAAGACTTCATCGGTGAAGTTCAAACTTCAGTATTCG
ATGCTGCAGCTGGTGTTGCACTAACTGACAAATTCGTTAAAGTTGTATCTTGGTACGACAACGAAATCGGTTACTCAAAC
AAAGTTCTTGACCTAATCGCTCACGTTTCTAAGTAA

Upstream 100 bases:

>100_bases
TAAATTTGGATTTTCACTTGCAGGTTGGCTCAGGATTTTGTAATTTTACTACCAGTTAATTTAAACCTGAAATTCAAATT
TAAGTTGTGGAGCAACTATA

Downstream 100 bases:

>100_bases
GCATTAGTTTAGACTTTCTTTGAAAGCTAACTTAAAAGGTTTTACTATCTTTTAAGAATGAAAGGCGACTTAATTGTCGC
CTTTTTTATACCTGTAATTC

Product: glyceraldehyde-3-phosphate dehydrogenase A

Products: NA

Alternate protein names: GAPDH-A [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVVDGNLVVNGKTVRVTAERNP
EDRKWDAINVDVVAEATGLFLDDATARKHITAGAKKVVLTGPSKDATPMFVMGVNHESYAGQDIVSNASCTTNCLAPVAK
VLNDKFGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSV
VDLTVNLKTAASYEAICAAMKEASEGELKGVLGYTEDAVVSQDFIGEVQTSVFDAAAGVALTDKFVKVVSWYDNEIGYSN
KVLDLIAHVSK

Sequences:

>Translated_331_residues
MTIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVVDGNLVVNGKTVRVTAERNP
EDRKWDAINVDVVAEATGLFLDDATARKHITAGAKKVVLTGPSKDATPMFVMGVNHESYAGQDIVSNASCTTNCLAPVAK
VLNDKFGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSV
VDLTVNLKTAASYEAICAAMKEASEGELKGVLGYTEDAVVSQDFIGEVQTSVFDAAAGVALTDKFVKVVSWYDNEIGYSN
KVLDLIAHVSK
>Mature_330_residues
TIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVVDGNLVVNGKTVRVTAERNPE
DRKWDAINVDVVAEATGLFLDDATARKHITAGAKKVVLTGPSKDATPMFVMGVNHESYAGQDIVSNASCTTNCLAPVAKV
LNDKFGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSVV
DLTVNLKTAASYEAICAAMKEASEGELKGVLGYTEDAVVSQDFIGEVQTSVFDAAAGVALTDKFVKVVSWYDNEIGYSNK
VLDLIAHVSK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=330, Percent_Identity=61.8181818181818, Blast_Score=420, Evalue=1e-118,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=59.3939393939394, Blast_Score=401, Evalue=1e-112,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=81.2688821752266, Blast_Score=552, Evalue=1e-158,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=40.7294832826748, Blast_Score=244, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=59.5808383233533, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=59.5808383233533, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=58.5074626865672, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=57.910447761194, Blast_Score=393, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=63.7462235649547, Blast_Score=434, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=63.7462235649547, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=64.0483383685801, Blast_Score=430, Evalue=1e-121,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=61.3981762917933, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=61.3981762917933, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=61.5853658536585, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=61.5853658536585, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=57.361963190184, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35171; Mature: 35040

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEV
CEEEEECCCHHHHHHHHHEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
VDGNLVVNGKTVRVTAERNPEDRKWDAINVDVVAEATGLFLDDATARKHITAGAKKVVLT
EECEEEECCEEEEEEECCCCCCCCCCEEEEEEEEECCCEEEECCHHHHHHCCCCCEEEEE
GPSKDATPMFVMGVNHESYAGQDIVSNASCTTNCLAPVAKVLNDKFGIESGLMTTVHATT
CCCCCCCEEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECC
ATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEHHHHHHHHHCEEEECCCCCEEE
VDLTVNLKTAASYEAICAAMKEASEGELKGVLGYTEDAVVSQDFIGEVQTSVFDAAAGVA
EEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHH
LTDKFVKVVSWYDNEIGYSNKVLDLIAHVSK
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEV
EEEEECCCHHHHHHHHHEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
VDGNLVVNGKTVRVTAERNPEDRKWDAINVDVVAEATGLFLDDATARKHITAGAKKVVLT
EECEEEECCEEEEEEECCCCCCCCCCEEEEEEEEECCCEEEECCHHHHHHCCCCCEEEEE
GPSKDATPMFVMGVNHESYAGQDIVSNASCTTNCLAPVAKVLNDKFGIESGLMTTVHATT
CCCCCCCEEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECC
ATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEHHHHHHHHHCEEEECCCCCEEE
VDLTVNLKTAASYEAICAAMKEASEGELKGVLGYTEDAVVSQDFIGEVQTSVFDAAAGVA
EEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHH
LTDKFVKVVSWYDNEIGYSNKVLDLIAHVSK
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]