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The map label for this gene is ltrA [H]

Identifier: 59711484

GI number: 59711484

Start: 961946

End: 962851

Strand: Reverse

Name: ltrA [H]

Synonym: VF_0877

Alternate gene names: 59711484

Gene position: 962851-961946 (Counterclockwise)

Preceding gene: 59711490

Following gene: 59711483

Centisome position: 33.23

GC content: 39.07

Gene sequence:

>906_bases
ATGATGGATTTAAATAACATCACACTATTAAACCAAGTTGTTGATTCTGGTAGCTTTACTCAAGCTGCAACGAATCTCGG
AATGACAAAATCAACAGTAAGCCGAAAATTAGCAGAGCTCGAAGAACACCTAGGTGTGAAGCTCATCACTCGTTCAACAC
GAAAATTAGGCCTAACTCAAGAAGGGGAAATCTTTTATCAAGCTAGCGTAAAAGTGCTCGATATCATGCAACAAACCGAG
TTAGAGCTCACCGCAAACCAAAACCTCATTCGTGGCCATCTCAATTTAGCCATGCCAGTAGAAATTGGACATAACGTCAT
GTCTGATTACATCAATAGCTTTTTAAAACATTATCCAGAGGTATCGATTAACCTTGAAATGACCAACCGTGAAGTGGATA
TCATTGGCGATAATATTGATCTTTACGTACAAATTGGGGAAATCAACGACTCTTCACTAGTGGCCAGAACCATTGATTTT
TCTGAGCGTATTATTGTTGCTAGCCCTGAGTATTTAAATAACTATGGGTATATTCAAACCCCAGAAGATCTCCAAGCCCC
TCATCATCAAATCCGAGTGGTGAACGCAGTTAAAGTGCCTAACCTTTACTTTAATCAGGTCGATAAAGCGATTCGAGTTA
ACTTACCCTATCGCTTAAAAGTCAACACAGTTACCGCTTGTAAATCCGCCTGTTTGAGTGGTTTAGGCATAGCTTCATTA
CCTGAATTCATCTGTCGTGAGCACATTAACAATGGAGAGTTAATACGAATTTTGCCTGATTGGGATTTACCACGAGTGGC
TATTAGCTTGGTGTTCCCTCAAAATAAATTGCTACCAAAACGATTAAGAGCTTTTATTGATCATGTACTTGAACGCTTTG
AATCAAAGAATGCAGCAAGAAAATAA

Upstream 100 bases:

>100_bases
TTGTGGATACAGAGTATAAAACTAAAAAGATTAATTGATTAGATAGGAAAAAAAGGAAACACTGTTGCATAATTCTTACT
AATGATTAGGTTACGCCCTT

Downstream 100 bases:

>100_bases
AGCGAAATAAACAACAAAAATTACATCAATTTTTATTAATCCATTAATTTCACTTGCCAGTAAGGCCATTCATCGAATAC
GATGCGATGGTCTATTATCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MMDLNNITLLNQVVDSGSFTQAATNLGMTKSTVSRKLAELEEHLGVKLITRSTRKLGLTQEGEIFYQASVKVLDIMQQTE
LELTANQNLIRGHLNLAMPVEIGHNVMSDYINSFLKHYPEVSINLEMTNREVDIIGDNIDLYVQIGEINDSSLVARTIDF
SERIIVASPEYLNNYGYIQTPEDLQAPHHQIRVVNAVKVPNLYFNQVDKAIRVNLPYRLKVNTVTACKSACLSGLGIASL
PEFICREHINNGELIRILPDWDLPRVAISLVFPQNKLLPKRLRAFIDHVLERFESKNAARK

Sequences:

>Translated_301_residues
MMDLNNITLLNQVVDSGSFTQAATNLGMTKSTVSRKLAELEEHLGVKLITRSTRKLGLTQEGEIFYQASVKVLDIMQQTE
LELTANQNLIRGHLNLAMPVEIGHNVMSDYINSFLKHYPEVSINLEMTNREVDIIGDNIDLYVQIGEINDSSLVARTIDF
SERIIVASPEYLNNYGYIQTPEDLQAPHHQIRVVNAVKVPNLYFNQVDKAIRVNLPYRLKVNTVTACKSACLSGLGIASL
PEFICREHINNGELIRILPDWDLPRVAISLVFPQNKLLPKRLRAFIDHVLERFESKNAARK
>Mature_301_residues
MMDLNNITLLNQVVDSGSFTQAATNLGMTKSTVSRKLAELEEHLGVKLITRSTRKLGLTQEGEIFYQASVKVLDIMQQTE
LELTANQNLIRGHLNLAMPVEIGHNVMSDYINSFLKHYPEVSINLEMTNREVDIIGDNIDLYVQIGEINDSSLVARTIDF
SERIIVASPEYLNNYGYIQTPEDLQAPHHQIRVVNAVKVPNLYFNQVDKAIRVNLPYRLKVNTVTACKSACLSGLGIASL
PEFICREHINNGELIRILPDWDLPRVAISLVFPQNKLLPKRLRAFIDHVLERFESKNAARK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=32.9861111111111, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=30.2083333333333, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=31.0810810810811, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87081978, Length=269, Percent_Identity=29.7397769516729, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789440, Length=261, Percent_Identity=26.0536398467433, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=25.6055363321799, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787589, Length=300, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789173, Length=181, Percent_Identity=26.5193370165746, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788706, Length=163, Percent_Identity=31.9018404907975, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788481, Length=297, Percent_Identity=25.5892255892256, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082132, Length=303, Percent_Identity=22.7722772277228, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786448, Length=291, Percent_Identity=23.7113402061856, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790011, Length=299, Percent_Identity=24.7491638795987, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=146, Percent_Identity=27.3972602739726, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=136, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34036; Mature: 34036

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDLNNITLLNQVVDSGSFTQAATNLGMTKSTVSRKLAELEEHLGVKLITRSTRKLGLTQ
CCCCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCHHHCCCCC
EGEIFYQASVKVLDIMQQTELELTANQNLIRGHLNLAMPVEIGHNVMSDYINSFLKHYPE
CCCEEEEEHHHHHHHHHHHCEEEECCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHCCC
VSINLEMTNREVDIIGDNIDLYVQIGEINDSSLVARTIDFSERIIVASPEYLNNYGYIQT
EEEEEEEECCEEEEEECCEEEEEEEECCCCCCEEEEEECCCCEEEEECCHHHCCCCCEEC
PEDLQAPHHQIRVVNAVKVPNLYFNQVDKAIRVNLPYRLKVNTVTACKSACLSGLGIASL
CHHHCCCCHHEEEEEEEECCCHHHHHCCCEEEECCCEEEEECHHHHHHHHHHCCCCHHHH
PEFICREHINNGELIRILPDWDLPRVAISLVFPQNKLLPKRLRAFIDHVLERFESKNAAR
HHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCC
K
C
>Mature Secondary Structure
MMDLNNITLLNQVVDSGSFTQAATNLGMTKSTVSRKLAELEEHLGVKLITRSTRKLGLTQ
CCCCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCHHHCCCCC
EGEIFYQASVKVLDIMQQTELELTANQNLIRGHLNLAMPVEIGHNVMSDYINSFLKHYPE
CCCEEEEEHHHHHHHHHHHCEEEECCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHCCC
VSINLEMTNREVDIIGDNIDLYVQIGEINDSSLVARTIDFSERIIVASPEYLNNYGYIQT
EEEEEEEECCEEEEEECCEEEEEEEECCCCCCEEEEEECCCCEEEEECCHHHCCCCCEEC
PEDLQAPHHQIRVVNAVKVPNLYFNQVDKAIRVNLPYRLKVNTVTACKSACLSGLGIASL
CHHHCCCCHHEEEEEEEECCCHHHHHCCCEEEECCCEEEEECHHHHHHHHHHCCCCHHHH
PEFICREHINNGELIRILPDWDLPRVAISLVFPQNKLLPKRLRAFIDHVLERFESKNAAR
HHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]