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The map label for this gene is argS [H]

Identifier: 59711446

GI number: 59711446

Start: 925737

End: 927470

Strand: Reverse

Name: argS [H]

Synonym: VF_0839

Alternate gene names: 59711446

Gene position: 927470-925737 (Counterclockwise)

Preceding gene: 59711448

Following gene: 59711444

Centisome position: 32.01

GC content: 42.45

Gene sequence:

>1734_bases
TTGAATATTCAATCACTTATTAACGACAAAGTTTCTCAAGCGTTAGAAGCAGCCGGTGCGCCAGCAGGCAGCCCTGCCGC
AGTACGTCAATCTGCAAAAGCACAATTTGGTGACTACCAAGCTAACGGCGTAATGGGCGTAGCTAAGCGACTAGGTACAA
ACCCACGAGAATTTGCTCAGAAAGTACTGGATGTTTTGGATCTTGATGGCATCGCTAGCAAAACTGAAATTGCAGGCCCT
GGCTTTATCAATATTTTCTTATCAGAAGAATTTCTAGCAAAACAAGCAGAAGCAGCATTAGCTGACGAACGCTTAGGTGT
TGCTAAAGAAGAACAACAAAACATCGTTGCAGACTACTCTGCACCAAACGTTGCTAAAGAAATGCACGTGGGTCACTTAC
GTTCAACTATCATTGGTGATGCTGTTGTTCGTACTCTTGAGTTTTTAGGTCACAACGTTACTCGTGCTAACCACATCGGT
GACTGGGGTACTCAGTTTGGTATGCTTATCGCAAACCTTGAGCGTATCCAAAAAGAGAAAGGCGAAGTTTCTATGGAACT
GTCTGATCTTGAAGGTTTCTACCGTGAATCTAAAAAACTGTATGACGAAGACGAAGAGTTTGCAGTAACCGCTCGTGGTT
ATGTTGTTAAACTTCAAAGCGGTGATGAGTTCTGCGCAGAAATGTGGAAGAAGCTTGTTGACGTTACTATGGTTCAAAAC
CAACGCAACTATGACCGTCTAAACGTATCACTTACTCGTGATAACGTAATGGGCGAAAGTATGTACAACAGCATGCTTGC
TCCAATTGTTGCTGATCTTCAAAAACAAGGTTTAGCTGTTGAGAGCGAAGGCGCTCAAGTTGTATTCCTAGATGAATACA
AAAACAAAGATGGTGAACCTATGGGTGTTATCGTTCAAAAACGTGACGGTGGCTTCCTATACACAACAACAGATATTGCT
TGTGCTAAATACCGTTACGAAGAACTGAATGCAGATCGTGTTCTTTACTTCATCGATTCACGTCAACACCAGCACTTAAT
GCAAGCTTGGACTATCGTTCGTAAAGCGGGCTATGTTCCTGAGAGCGTATCTCTAGAGCACCATGCATTTGGTATGATGC
TAGGTAAAGATGGTCGCCCATTTAAAACTCGTGCAGGCGGTACAGTTCGTCTAGCTGATCTTCTTGATGAAGCTGAAGAA
CGTGCAACAAAACTGATCGAAGAGAAAAACAAAGATCTATCTGCTGAAGAAAAAGCAAAAATTGCTACAACCGTTGCAAT
GGCAGCAGTTAAGTACTCAGATCTTTCTAAGCACCGTACTACGGATTACATCTTCGATTGGGATAACATGCTTGCGTTCG
AAGGTAACACAGCGCCTTACATGCAATATGCATACACTCGTGTAGCTTCTATCTTCAGCAAAGCTGGCTTATCTATGGAT
GAGTTAACAGGTGAAGTTAAGATCACAGATGAGAAAGAAAAAGCGTTAGTTGCTAAGTTAATGCAATTTGAAGAAGCGGT
TCAAGCTGTAGCAAGTGAAGGTCAACCTCACCTAATGTGTGCTTACCTATTTGAACTTGCTGGTCAATTCTCTAGCTTCT
ACGAAGCGTGCCCTATTCTTAACAACGAAGATGATGCTGTTAAGCAAAGCCGCCTGAAGTTAGCTGCATTAACAGCGAAA
ACAATTAAGCAAGGCTTAGAACTACTAGGTATTGAAACGCTAGAGCGTATGTAA

Upstream 100 bases:

>100_bases
AAACTATTAAATATCCCCTGTTTTATTGCTATTATTAGCGATTATTTTGCTTTCCATGCAATAGCATTCCTGTTTAACAG
CGATATGAAGGATAACCTCT

Downstream 100 bases:

>100_bases
TTCCTATTTTAACAATCTGAATACTCATTCAGATTGTTGATAACTAAAGATCAAAAAAGGAGCTAAAATTAGCTCCTTTT
TTATTATCTATACTTTATGT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQKVLDVLDLDGIASKTEIAGP
GFINIFLSEEFLAKQAEAALADERLGVAKEEQQNIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIG
DWGTQFGMLIANLERIQKEKGEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQSGDEFCAEMWKKLVDVTMVQN
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQKQGLAVESEGAQVVFLDEYKNKDGEPMGVIVQKRDGGFLYTTTDIA
CAKYRYEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEE
RATKLIEEKNKDLSAEEKAKIATTVAMAAVKYSDLSKHRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFSKAGLSMD
ELTGEVKITDEKEKALVAKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPILNNEDDAVKQSRLKLAALTAK
TIKQGLELLGIETLERM

Sequences:

>Translated_577_residues
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQKVLDVLDLDGIASKTEIAGP
GFINIFLSEEFLAKQAEAALADERLGVAKEEQQNIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIG
DWGTQFGMLIANLERIQKEKGEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQSGDEFCAEMWKKLVDVTMVQN
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQKQGLAVESEGAQVVFLDEYKNKDGEPMGVIVQKRDGGFLYTTTDIA
CAKYRYEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEE
RATKLIEEKNKDLSAEEKAKIATTVAMAAVKYSDLSKHRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFSKAGLSMD
ELTGEVKITDEKEKALVAKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPILNNEDDAVKQSRLKLAALTAK
TIKQGLELLGIETLERM
>Mature_577_residues
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQKVLDVLDLDGIASKTEIAGP
GFINIFLSEEFLAKQAEAALADERLGVAKEEQQNIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIG
DWGTQFGMLIANLERIQKEKGEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQSGDEFCAEMWKKLVDVTMVQN
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQKQGLAVESEGAQVVFLDEYKNKDGEPMGVIVQKRDGGFLYTTTDIA
CAKYRYEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEE
RATKLIEEKNKDLSAEEKAKIATTVAMAAVKYSDLSKHRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFSKAGLSMD
ELTGEVKITDEKEKALVAKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPILNNEDDAVKQSRLKLAALTAK
TIKQGLELLGIETLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=596, Percent_Identity=38.255033557047, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI197100773, Length=528, Percent_Identity=28.219696969697, Blast_Score=206, Evalue=5e-53,
Organism=Escherichia coli, GI1788184, Length=579, Percent_Identity=72.7115716753022, Blast_Score=874, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=38.3193277310924, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71985068, Length=563, Percent_Identity=38.898756660746, Blast_Score=370, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17532153, Length=489, Percent_Identity=26.1758691206544, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320548, Length=543, Percent_Identity=32.2283609576427, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6321883, Length=527, Percent_Identity=29.0322580645161, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI18859963, Length=567, Percent_Identity=39.1534391534392, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28571570, Length=483, Percent_Identity=30.2277432712215, Blast_Score=176, Evalue=4e-44,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64102; Mature: 64102

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQ
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHH
KVLDVLDLDGIASKTEIAGPGFINIFLSEEFLAKQAEAALADERLGVAKEEQQNIVADYS
HHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHCCEEECCC
APNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIGDWGTQFGMLIANLERIQKEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQSGDEFCAEMWKKLVDVTMVQN
CCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHC
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQKQGLAVESEGAQVVFLDEYKNKDGEP
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCC
MGVIVQKRDGGFLYTTTDIACAKYRYEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVP
EEEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
ESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEERATKLIEEKNKDLSAEEKAK
CCCCCCHHHHEEEECCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IATTVAMAAVKYSDLSKHRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFSKAGLSMD
HHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHH
ELTGEVKITDEKEKALVAKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPIL
HCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NNEDDAVKQSRLKLAALTAKTIKQGLELLGIETLERM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQ
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHH
KVLDVLDLDGIASKTEIAGPGFINIFLSEEFLAKQAEAALADERLGVAKEEQQNIVADYS
HHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHCCEEECCC
APNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIGDWGTQFGMLIANLERIQKEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQSGDEFCAEMWKKLVDVTMVQN
CCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHC
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQKQGLAVESEGAQVVFLDEYKNKDGEP
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCC
MGVIVQKRDGGFLYTTTDIACAKYRYEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVP
EEEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
ESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEERATKLIEEKNKDLSAEEKAK
CCCCCCHHHHEEEECCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IATTVAMAAVKYSDLSKHRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFSKAGLSMD
HHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHH
ELTGEVKITDEKEKALVAKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPIL
HCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NNEDDAVKQSRLKLAALTAKTIKQGLELLGIETLERM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA