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The map label for this gene is yclF [H]

Identifier: 59711409

GI number: 59711409

Start: 878848

End: 880203

Strand: Reverse

Name: yclF [H]

Synonym: VF_0802

Alternate gene names: 59711409

Gene position: 880203-878848 (Counterclockwise)

Preceding gene: 59711411

Following gene: 59711398

Centisome position: 30.38

GC content: 40.27

Gene sequence:

>1356_bases
ATGTCAAATAACAACAAATTACTTATGGGACACCCTCAAGGGTTGTTCTTACTTTTTGGAACAGAGCTTTGGGAACGCTT
CTCCTATTACGCAATGCGCGCTATCTTGGTTCTATATCTCACAGATAGAACCATCAATGGTGGTATGGGTTGGACAGTAA
AAGATGCATTAAGCCTATATGGTACTTATACCGCCCTTATGTACATCACCCCTCTCATTGGCGGATGGTTAGCTGATAAT
TACTTAGGCCAACGTAAAGCATTATTAATCGGTGGTTTCTTAATGGTAATTGGTCAATTTACTTTGGCTTTACCGCACGA
TTTCCTTCCTTTTTCTGTCGAAGCCTTATTTTATACCGGTCTTGGTTTTCTAATCGCTGGTAATGGTTTATTTAAACCAA
ATGTTTCCACAATGGTTGGTGATTTATATGAAGATGGCGATCATCGTCGTGATGGCGCATTTACTATCTTCTACATGGGT
ATTAACTTAGGTTCTTTACTTGCTGGTGTTGTTTCAGGCTCTGTAACTGGAGTATGGGGATGGAAAGCTGGTTTTGTTGC
AGCTGGTATCGGTATGATCATCAGTTTGATCATCCAAAGTCTTTTTGCCCAACGCTTCTTAGGTGACATAGGTGTTAGAC
CTGCAGCACATATCGCAAAAGAAAACGCAAAAGCAGCTGGTAAATCAAGCACAGCGTTAACTAAAGAAGAAATTGACCGA
CTAAAAGTGGTCATGATCATGGGCTTATTCGTTATTGTTTTCTGGGCAGGCTTTGAACAAGCTGGTGGCCTAATGAATGT
ATATTCACAACAATACACAGATAGAATGATTGGTTCTTTTGAAGTTCCTGCAGCTTGGTTCCAATCGTTAAACCCGTTCT
TTATTATTGTTCTTGCTCCTATCATTGCTGGGATATGGGTTAAACTCGGTCCAAAAGAGCCAAGCTCACCAGTTAAATTT
GCGATGGCTCTATTCTTCTTGGCTATGGGTTTCGTATGTATGGTTGGCGCAGTACTAGAACAAGGTGGCGACTTAACCGT
TAAAACTTCAATGCTTTGGTTAGTTGGTGCGTATTTCTTCCATACTTTAGGCGAACTGTGTTTATCACCAATTGGTCTTT
CATTAGTTACTAAATTAGCTCCATTACGTTTAGCTTCATTAATGATGGGTACTTGGTTTGGTTTCAATGCTATCTCTAAC
TACATTGCAGGCTTAGTAGGCTCACATGTTGAAAGCTTAGGTGCTCTAGATATCTTTGCTGGTATTGCTATCACGGCAAC
AGTTTCTGGTGTTCTTCTTCTGATAATTTCAGGTACACTTATTCGTTGGATGCACGGTGCTGAAAAAGCTCATTAA

Upstream 100 bases:

>100_bases
CAAATCACATAAAAATGTACGACATTGCAGTAACGACATTCAAAGCGTATAAATTTACGCTGTATAAGAAGAATAATATT
CCATTATAAAAGAGAACATT

Downstream 100 bases:

>100_bases
TCGGTAATTCCAAACTGAATATCAAATATTCAGAATACGATTTAGCACAAAAAAGCAGCCTTCATGGCTGCCTTTTTATT
GTACCAATGAGCTGATTAGC

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGMGWTVKDALSLYGTYTALMYITPLIGGWLADN
YLGQRKALLIGGFLMVIGQFTLALPHDFLPFSVEALFYTGLGFLIAGNGLFKPNVSTMVGDLYEDGDHRRDGAFTIFYMG
INLGSLLAGVVSGSVTGVWGWKAGFVAAGIGMIISLIIQSLFAQRFLGDIGVRPAAHIAKENAKAAGKSSTALTKEEIDR
LKVVMIMGLFVIVFWAGFEQAGGLMNVYSQQYTDRMIGSFEVPAAWFQSLNPFFIIVLAPIIAGIWVKLGPKEPSSPVKF
AMALFFLAMGFVCMVGAVLEQGGDLTVKTSMLWLVGAYFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISN
YIAGLVGSHVESLGALDIFAGIAITATVSGVLLLIISGTLIRWMHGAEKAH

Sequences:

>Translated_451_residues
MSNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGMGWTVKDALSLYGTYTALMYITPLIGGWLADN
YLGQRKALLIGGFLMVIGQFTLALPHDFLPFSVEALFYTGLGFLIAGNGLFKPNVSTMVGDLYEDGDHRRDGAFTIFYMG
INLGSLLAGVVSGSVTGVWGWKAGFVAAGIGMIISLIIQSLFAQRFLGDIGVRPAAHIAKENAKAAGKSSTALTKEEIDR
LKVVMIMGLFVIVFWAGFEQAGGLMNVYSQQYTDRMIGSFEVPAAWFQSLNPFFIIVLAPIIAGIWVKLGPKEPSSPVKF
AMALFFLAMGFVCMVGAVLEQGGDLTVKTSMLWLVGAYFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISN
YIAGLVGSHVESLGALDIFAGIAITATVSGVLLLIISGTLIRWMHGAEKAH
>Mature_450_residues
SNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGMGWTVKDALSLYGTYTALMYITPLIGGWLADNY
LGQRKALLIGGFLMVIGQFTLALPHDFLPFSVEALFYTGLGFLIAGNGLFKPNVSTMVGDLYEDGDHRRDGAFTIFYMGI
NLGSLLAGVVSGSVTGVWGWKAGFVAAGIGMIISLIIQSLFAQRFLGDIGVRPAAHIAKENAKAAGKSSTALTKEEIDRL
KVVMIMGLFVIVFWAGFEQAGGLMNVYSQQYTDRMIGSFEVPAAWFQSLNPFFIIVLAPIIAGIWVKLGPKEPSSPVKFA
MALFFLAMGFVCMVGAVLEQGGDLTVKTSMLWLVGAYFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISNY
IAGLVGSHVESLGALDIFAGIAITATVSGVLLLIISGTLIRWMHGAEKAH

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=390, Percent_Identity=28.7179487179487, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI226371746, Length=345, Percent_Identity=24.3478260869565, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI226371748, Length=340, Percent_Identity=23.2352941176471, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1787922, Length=482, Percent_Identity=29.8755186721992, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1789911, Length=448, Percent_Identity=27.6785714285714, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786927, Length=491, Percent_Identity=27.0875763747454, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1790572, Length=473, Percent_Identity=27.6955602536998, Blast_Score=168, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71987453, Length=336, Percent_Identity=27.0833333333333, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17569141, Length=379, Percent_Identity=25.5936675461741, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17541704, Length=345, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322946, Length=475, Percent_Identity=21.0526315789474, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571098, Length=326, Percent_Identity=26.0736196319018, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28571102, Length=326, Percent_Identity=26.0736196319018, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28571100, Length=326, Percent_Identity=26.0736196319018, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24639583, Length=340, Percent_Identity=27.3529411764706, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639585, Length=340, Percent_Identity=27.3529411764706, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639581, Length=340, Percent_Identity=27.3529411764706, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 48801; Mature: 48670

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGMGWTVKDALSLY
CCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHH
GTYTALMYITPLIGGWLADNYLGQRKALLIGGFLMVIGQFTLALPHDFLPFSVEALFYTG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
LGFLIAGNGLFKPNVSTMVGDLYEDGDHRRDGAFTIFYMGINLGSLLAGVVSGSVTGVWG
HHHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEECC
WKAGFVAAGIGMIISLIIQSLFAQRFLGDIGVRPAAHIAKENAKAAGKSSTALTKEEIDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
LKVVMIMGLFVIVFWAGFEQAGGLMNVYSQQYTDRMIGSFEVPAAWFQSLNPFFIIVLAP
HHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHH
IIAGIWVKLGPKEPSSPVKFAMALFFLAMGFVCMVGAVLEQGGDLTVKTSMLWLVGAYFF
HHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
HTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISNYIAGLVGSHVESLGALDIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAITATVSGVLLLIISGTLIRWMHGAEKAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGMGWTVKDALSLY
CCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHH
GTYTALMYITPLIGGWLADNYLGQRKALLIGGFLMVIGQFTLALPHDFLPFSVEALFYTG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
LGFLIAGNGLFKPNVSTMVGDLYEDGDHRRDGAFTIFYMGINLGSLLAGVVSGSVTGVWG
HHHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEECC
WKAGFVAAGIGMIISLIIQSLFAQRFLGDIGVRPAAHIAKENAKAAGKSSTALTKEEIDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
LKVVMIMGLFVIVFWAGFEQAGGLMNVYSQQYTDRMIGSFEVPAAWFQSLNPFFIIVLAP
HHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHH
IIAGIWVKLGPKEPSSPVKFAMALFFLAMGFVCMVGAVLEQGGDLTVKTSMLWLVGAYFF
HHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
HTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISNYIAGLVGSHVESLGALDIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAITATVSGVLLLIISGTLIRWMHGAEKAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]