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The map label for this gene is 59711183

Identifier: 59711183

GI number: 59711183

Start: 628625

End: 629656

Strand: Reverse

Name: 59711183

Synonym: VF_0576

Alternate gene names: NA

Gene position: 629656-628625 (Counterclockwise)

Preceding gene: 59711184

Following gene: 59711182

Centisome position: 21.73

GC content: 43.12

Gene sequence:

>1032_bases
ATGGCTCATTTTGCTCTTGCCTTTGGTACAGCGACAAAAAACCGCGACAATAAAATTATTGAAGCTTTCTTCCCTCACCC
AGTACTTAACCCTTCTGATGCACTAGTTTCGGCAATTGCACAAGCAAGTGGTTACGCTGAAGGCAACCAAGCGATCGAAA
TTTCTTCTGAAGTTTGTACTGAACTTGCTAACGCATTTGCAGCAAGCGGTGATGTTGCTAACGCAGCATTTGCAGAAAAA
GCAGTTCAATCTAAACAGCCATTAGTTCTTGTTGTTTTAGCTACTGATGAGCAACCTCAATCTGTTGCTGAAGGTTTCTT
AAAGCTTCAACTTATCTCTAACCGTTTAGTTAAACCACACGGTACTGTTCTAGATGGTATCTTTGGTCTTCTACATAACA
TTGCTTGGACTAACCAAGGTCCAATCGATTTACCTGAACTTGCTGATCGTCAAATCGAAGCTCGTTTAGCCGGCGAAACA
CTAACTGTAGATTGCGTTGATAAATTCCCTAAAATGGTGGATTACGTGGTTCCTACTGGTGTTCGTATTGCTGATACTTC
ACGTGTTCGCCTAGGTGCTCATGTAGGTGAAGGCACAACAGTTATGCACGAAGGTTTCATCAACTTTAACGCTGGTACTA
CGGGTGTTAGCATGGTTGAAGGCCGTATTTCTGCTGGTGTTGTTGTTGGCAATGGTTCAGATATCGGCGGTGGTGCTTCT
ATCATGGGTACACTTTCTGGCGGCGGTAAAATGGTTATCTCTATTGGTGAGAACTGTCTACTTGGTGCTAATGCCGGCCT
TGGTTTCCCAATGGGCGATCGTTGTACGATTGAATCTGGCCTATATGTTACTGCTGGCACAAAAGTGAGCATGCTAGACA
ATCAAGGCAAAGAAGTTGAAATTGCGAAAGCTCGTGATCTTGCTGGTAAAACCGATCTTCTATTCCGTCGTAACTCTATC
ACTGGTCAAATCGAGTGTTTAACGAACAAATCAGCAGTTGAACTAAATAGCGAATTGCACAGCAATAACTAA

Upstream 100 bases:

>100_bases
TTATGGTTTCGCTCTTCTATATCACAGCAACTCTCTTTATGATGTGAAGTAAGATTTATTTTTAAATACTAATATTTATA
TGGAAATGGAGAATCATTAC

Downstream 100 bases:

>100_bases
TTTTTTAACTGGATTATATGAATAAGGTATTCAGACTCTATTCATAAAGACCAAGGTAATCTTATGGCCAGTAGCGTAAT
TGTTACTGGCCATTTTTTAT

Product: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase

Products: CoA; (R)-2-(succinylamino)-6-oxoheptanedioate

Alternate protein names: Transferase; Tetrahydrodipicolinate Succinylase; Tetrahydropicolinate Succinylase; Tetrahydrodipicolinate N- Succinyltransferase; Transferase Hexapeptide Repeat Containing Protein; Succinyltransferase; Succinyl-Transferase; Tranferase; Tetrahydrodipicolinate N-Succinyltransferase-Like Protein; Lysine Biosynthesis-Like Protein; Transferase Tetrahydrodipicolinate N-Succinyltransferase

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MAHFALAFGTATKNRDNKIIEAFFPHPVLNPSDALVSAIAQASGYAEGNQAIEISSEVCTELANAFAASGDVANAAFAEK
AVQSKQPLVLVVLATDEQPQSVAEGFLKLQLISNRLVKPHGTVLDGIFGLLHNIAWTNQGPIDLPELADRQIEARLAGET
LTVDCVDKFPKMVDYVVPTGVRIADTSRVRLGAHVGEGTTVMHEGFINFNAGTTGVSMVEGRISAGVVVGNGSDIGGGAS
IMGTLSGGGKMVISIGENCLLGANAGLGFPMGDRCTIESGLYVTAGTKVSMLDNQGKEVEIAKARDLAGKTDLLFRRNSI
TGQIECLTNKSAVELNSELHSNN

Sequences:

>Translated_343_residues
MAHFALAFGTATKNRDNKIIEAFFPHPVLNPSDALVSAIAQASGYAEGNQAIEISSEVCTELANAFAASGDVANAAFAEK
AVQSKQPLVLVVLATDEQPQSVAEGFLKLQLISNRLVKPHGTVLDGIFGLLHNIAWTNQGPIDLPELADRQIEARLAGET
LTVDCVDKFPKMVDYVVPTGVRIADTSRVRLGAHVGEGTTVMHEGFINFNAGTTGVSMVEGRISAGVVVGNGSDIGGGAS
IMGTLSGGGKMVISIGENCLLGANAGLGFPMGDRCTIESGLYVTAGTKVSMLDNQGKEVEIAKARDLAGKTDLLFRRNSI
TGQIECLTNKSAVELNSELHSNN
>Mature_342_residues
AHFALAFGTATKNRDNKIIEAFFPHPVLNPSDALVSAIAQASGYAEGNQAIEISSEVCTELANAFAASGDVANAAFAEKA
VQSKQPLVLVVLATDEQPQSVAEGFLKLQLISNRLVKPHGTVLDGIFGLLHNIAWTNQGPIDLPELADRQIEARLAGETL
TVDCVDKFPKMVDYVVPTGVRIADTSRVRLGAHVGEGTTVMHEGFINFNAGTTGVSMVEGRISAGVVVGNGSDIGGGASI
MGTLSGGGKMVISIGENCLLGANAGLGFPMGDRCTIESGLYVTAGTKVSMLDNQGKEVEIAKARDLAGKTDLLFRRNSIT
GQIECLTNKSAVELNSELHSNN

Specific function: Unknown

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.117

Molecular weight: Translated: 35880; Mature: 35749

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHFALAFGTATKNRDNKIIEAFFPHPVLNPSDALVSAIAQASGYAEGNQAIEISSEVCT
CCEEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECHHHHH
ELANAFAASGDVANAAFAEKAVQSKQPLVLVVLATDEQPQSVAEGFLKLQLISNRLVKPH
HHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHEEHHCCCCCCC
GTVLDGIFGLLHNIAWTNQGPIDLPELADRQIEARLAGETLTVDCVDKFPKMVDYVVPTG
CHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHCCCC
VRIADTSRVRLGAHVGEGTTVMHEGFINFNAGTTGVSMVEGRISAGVVVGNGSDIGGGAS
EEEECCCCEEEEEECCCCCEEEEECEEEECCCCCCHHEEECCEEEEEEEECCCCCCCCEE
IMGTLSGGGKMVISIGENCLLGANAGLGFPMGDRCTIESGLYVTAGTKVSMLDNQGKEVE
EEEEECCCCEEEEEECCCEEEECCCCCCCCCCCCEEECCCEEEEECCEEEEECCCCCEEE
IAKARDLAGKTDLLFRRNSITGQIECLTNKSAVELNSELHSNN
EEHHHCCCCCCCEEEEECCCCEEEEEECCCCCEEECCHHCCCC
>Mature Secondary Structure 
AHFALAFGTATKNRDNKIIEAFFPHPVLNPSDALVSAIAQASGYAEGNQAIEISSEVCT
CEEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECHHHHH
ELANAFAASGDVANAAFAEKAVQSKQPLVLVVLATDEQPQSVAEGFLKLQLISNRLVKPH
HHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHEEHHCCCCCCC
GTVLDGIFGLLHNIAWTNQGPIDLPELADRQIEARLAGETLTVDCVDKFPKMVDYVVPTG
CHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHCCCC
VRIADTSRVRLGAHVGEGTTVMHEGFINFNAGTTGVSMVEGRISAGVVVGNGSDIGGGAS
EEEECCCCEEEEEECCCCCEEEEECEEEECCCCCCHHEEECCEEEEEEEECCCCCCCCEE
IMGTLSGGGKMVISIGENCLLGANAGLGFPMGDRCTIESGLYVTAGTKVSMLDNQGKEVE
EEEEECCCCEEEEEECCCEEEECCCCCCCCCCCCEEECCCEEEEECCEEEEECCCCCEEE
IAKARDLAGKTDLLFRRNSITGQIECLTNKSAVELNSELHSNN
EEHHHCCCCCCCEEEEECCCCEEEEEECCCCCEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinyl-CoA; (R)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate; H2O

Specific reaction: succinyl-CoA + (R)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + (R)-2-(succinylamino)-6-oxoheptanedioate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA