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The map label for this gene is codA [H]

Identifier: 59711138

GI number: 59711138

Start: 568710

End: 569987

Strand: Reverse

Name: codA [H]

Synonym: VF_0531

Alternate gene names: 59711138

Gene position: 569987-568710 (Counterclockwise)

Preceding gene: 59711139

Following gene: 59711137

Centisome position: 19.67

GC content: 38.58

Gene sequence:

>1278_bases
ATGACAAATTTATTAATAAAAAACGTAGCTCTACGAGATCAAGAAGGTTTATTTCAGATCTTGATTGAAGATGGTCAATT
CAAAACCATTACTAACAATGAGCAAGCACTCTCCTATTCTGGTGACATTCTTGATGCTGAAGGTGGTTTAGCCAACGCTC
CATTTTGCGAACCTCATATTCATTTAGATACGACTCAAACGGCTGGTGAACCAAGCTGGAATATTTCAGGTACCTTATTT
GAGGGAATTGAACGTTGGGCTGAGCGTAAAGAACTATTATCTATTGAAGATGTAAAAACACGCGCTAAACAAACATTAAA
ATGGCAAATTGCTAACGGTATTCAGCACGTTCGTACTCACGTTGATGTTTCAGATCCGACACTGATTGCATTAAAAGCAA
TGCTTGAAGTAAAAGAAGAAATGAAAGAATGGGTTGATATCCAAATCGTTGCTTTTCCTCAAGAAGGCATTCTTTCTTAC
CCTAATGGTAAAGAGTTACTTGAAGAGGCAGTACAACTAGGCGCAGATGTTATTGGCGCTATTCCTCATTTTGAGTTTAC
TCGTGAATACGGTGTCGAATCTCTTCACTATATTTTTGAATTAGCAAAAAAATATGACCGTCTAATTGATGTTCACTGTG
ATGAAATCGATGATGAGCAATCACGTTTTGTTGAAACTGTTGCCGCTCTTGCTCATAAATTCAATATGGGTGAAAAGGTA
ACAGCAAGTCATACGACAGCAATGCATTCATATAATGGTGCTTATGCTTCTCGCTTATTCCGCTTACTTAGAATGTCTGG
TATTAACTTTGTTGCGAATCCACTTGTTAATATCCACCTACAAGGTCGTTTTGATGATTACCCTAAGCGTCGTGGTATTA
CACGCGTGAAAGAGATGCTAGCAAACAATATTAACGTTTGTTTTGGTCATGACGATGTATTTGACCCATGGTATCCGTTA
GGCACAGCTAACATGCTACAAGTTCTTCATATGGGACTGCATGTCTGTCAAATCATGGGATACGACCAAATTAACCAAGG
TCTTGATCTAATCAGCTATAAATCGGCTCGAACTCTAAATATTCAAGATAACTACGGCATCGAAGAAGGCAAACCGGGTA
ACTTAATTATCTTACCTGCTGAAAATGGATTTGATGCTCTACGTCGCCAAGTTCCGGTTCGTTTCTCTATTCGCCACGGT
AAAGTAATATCAGAAACTCAACCAGCAACGACTACGATTACATTAGATAAAGCTGAGACGGTTTCATTTAAACGCTAA

Upstream 100 bases:

>100_bases
TAAACGCTGTATTAGGCGGAGCGATTAGCTACCTATTACTAAACCCAATGATTAACAAAAAATCGATCTCTGAAACAGAA
ACAGTATAGAAGATACAGCA

Downstream 100 bases:

>100_bases
GTCATTACCATCTTAAGTAATAAGGGAGCTATCGCTCCCTTTTTTATTGTTACTATCTTCATAGTGATATACTTACTTTA
TATTCTTATTCAATGGCATT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTNLLIKNVALRDQEGLFQILIEDGQFKTITNNEQALSYSGDILDAEGGLANAPFCEPHIHLDTTQTAGEPSWNISGTLF
EGIERWAERKELLSIEDVKTRAKQTLKWQIANGIQHVRTHVDVSDPTLIALKAMLEVKEEMKEWVDIQIVAFPQEGILSY
PNGKELLEEAVQLGADVIGAIPHFEFTREYGVESLHYIFELAKKYDRLIDVHCDEIDDEQSRFVETVAALAHKFNMGEKV
TASHTTAMHSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLANNINVCFGHDDVFDPWYPL
GTANMLQVLHMGLHVCQIMGYDQINQGLDLISYKSARTLNIQDNYGIEEGKPGNLIILPAENGFDALRRQVPVRFSIRHG
KVISETQPATTTITLDKAETVSFKR

Sequences:

>Translated_425_residues
MTNLLIKNVALRDQEGLFQILIEDGQFKTITNNEQALSYSGDILDAEGGLANAPFCEPHIHLDTTQTAGEPSWNISGTLF
EGIERWAERKELLSIEDVKTRAKQTLKWQIANGIQHVRTHVDVSDPTLIALKAMLEVKEEMKEWVDIQIVAFPQEGILSY
PNGKELLEEAVQLGADVIGAIPHFEFTREYGVESLHYIFELAKKYDRLIDVHCDEIDDEQSRFVETVAALAHKFNMGEKV
TASHTTAMHSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLANNINVCFGHDDVFDPWYPL
GTANMLQVLHMGLHVCQIMGYDQINQGLDLISYKSARTLNIQDNYGIEEGKPGNLIILPAENGFDALRRQVPVRFSIRHG
KVISETQPATTTITLDKAETVSFKR
>Mature_424_residues
TNLLIKNVALRDQEGLFQILIEDGQFKTITNNEQALSYSGDILDAEGGLANAPFCEPHIHLDTTQTAGEPSWNISGTLFE
GIERWAERKELLSIEDVKTRAKQTLKWQIANGIQHVRTHVDVSDPTLIALKAMLEVKEEMKEWVDIQIVAFPQEGILSYP
NGKELLEEAVQLGADVIGAIPHFEFTREYGVESLHYIFELAKKYDRLIDVHCDEIDDEQSRFVETVAALAHKFNMGEKVT
ASHTTAMHSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLANNINVCFGHDDVFDPWYPLG
TANMLQVLHMGLHVCQIMGYDQINQGLDLISYKSARTLNIQDNYGIEEGKPGNLIILPAENGFDALRRQVPVRFSIRHGK
VISETQPATTTITLDKAETVSFKR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=420, Percent_Identity=76.6666666666667, Blast_Score=675, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=332, Percent_Identity=24.6987951807229, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47995; Mature: 47864

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLLIKNVALRDQEGLFQILIEDGQFKTITNNEQALSYSGDILDAEGGLANAPFCEPHI
CCCEEEEHHHHCCCCCEEEEEEECCCEEEECCCCCEEEECCCEEECCCCCCCCCCCCCCE
HLDTTQTAGEPSWNISGTLFEGIERWAERKELLSIEDVKTRAKQTLKWQIANGIQHVRTH
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VDVSDPTLIALKAMLEVKEEMKEWVDIQIVAFPQEGILSYPNGKELLEEAVQLGADVIGA
CCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHC
IPHFEFTREYGVESLHYIFELAKKYDRLIDVHCDEIDDEQSRFVETVAALAHKFNMGEKV
CCCHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
TASHTTAMHSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEML
ECHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCHHHCCHHHHHHHH
ANNINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQIMGYDQINQGLDLISYKSARTLN
HCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCEEEE
IQDNYGIEEGKPGNLIILPAENGFDALRRQVPVRFSIRHGKVISETQPATTTITLDKAET
ECCCCCCCCCCCCCEEEEECCCCHHHHHHCCCEEEEEECCCEECCCCCCEEEEEECCCCC
VSFKR
CCCCC
>Mature Secondary Structure 
TNLLIKNVALRDQEGLFQILIEDGQFKTITNNEQALSYSGDILDAEGGLANAPFCEPHI
CCEEEEHHHHCCCCCEEEEEEECCCEEEECCCCCEEEECCCEEECCCCCCCCCCCCCCE
HLDTTQTAGEPSWNISGTLFEGIERWAERKELLSIEDVKTRAKQTLKWQIANGIQHVRTH
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VDVSDPTLIALKAMLEVKEEMKEWVDIQIVAFPQEGILSYPNGKELLEEAVQLGADVIGA
CCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHC
IPHFEFTREYGVESLHYIFELAKKYDRLIDVHCDEIDDEQSRFVETVAALAHKFNMGEKV
CCCHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
TASHTTAMHSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEML
ECHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCHHHCCHHHHHHHH
ANNINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQIMGYDQINQGLDLISYKSARTLN
HCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCEEEE
IQDNYGIEEGKPGNLIILPAENGFDALRRQVPVRFSIRHGKVISETQPATTTITLDKAET
ECCCCCCCCCCCCCEEEEECCCCHHHHHHCCCEEEEEECCCEECCCCCCEEEEEECCCCC
VSFKR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]