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The map label for this gene is gmr [C]

Identifier: 59711101

GI number: 59711101

Start: 531563

End: 533590

Strand: Reverse

Name: gmr [C]

Synonym: VF_0494

Alternate gene names: 59711101

Gene position: 533590-531563 (Counterclockwise)

Preceding gene: 59711104

Following gene: 59711100

Centisome position: 18.42

GC content: 37.57

Gene sequence:

>2028_bases
ATGTCTCTTTCTCAAATACAACATTGGCTTCCTTTGCTTACAGATAACAGTCCATTTCTGTTTGCTATTTTGGACAAAGA
CCATAAATACATAACAGTAAACAACCGTTACTGTGAACTTAGTGGATTAAACCGTGAATCTCTTTGTGGCCGAAGCGATT
CTGAAATTTTAGGCAAACATTTTTACTCATCATTAAAAGCCTATTATGACAGAGCTCTAAACGGTGAAAAAATTGAAGCG
GAAATTACGCTAGATGATCATCGATTTGATACCAGTCTACATTTTAGTCTCTTCCCTATTCATGAAGAAGATACGACTTA
TATTGTATTTCACGCTGTCGACACTTCAGAACGCCAACAACTTCTCAACTCTCTAAAAGAAAGTGAATCTAAGTACCACA
AACTCACAGAGCTATTAAGTGACTCCGTCTTTTTAATTGAAGGAGATATTATTGTCTCTGCAAACGGAGCGTCAGCTAAA
ATGCTTGGGTTCAACAATCCAACAGAATTTATTGGCGAAAGTATTGAGCAACTTTTACATTCCCCTTCTCGCACTCAATG
CTTATCAGAATTAATTTCAAGCTTACCTTCTGAACAACAGTTAACCGTTAGAACAACGGCGAATTGCTCTCTTCGTGCCG
AATTAATATTAACGGTTGAAGAAACTCACATATTAGGAAGCCCTGCTCATCTTGTTATTTTAAAAGAAAACAAGAAGCAA
ATTGCAATGAGCAACCATATTGCCGCTTCTCAAGTTGATCTATTGACTGGGATTTACAATCGCCACGGTTTTACCCATGT
TATAGAAAAGATGATTAAGGAAGACATTCCTTTTTTCATGCTTTATTTAGATATTGATAACTTCAAGAATATTAATGATT
CACTTGGTCATCATATTGGAGATCGTGTTTTAAAAGAGATCTCCAATCGCTTACAGAAATTACTGCCAAAACACGCTGTT
GTTGGCCATTTAGGTGGCGATGAATTTGGAATACTATTTCCAAAACCAGAACACAACCAAGTTCTTGAGCAATTATCTGA
AAAGATCATCAGTTTAATCAACCAACCATTCGATCTTGTTCACTTTTCAAAACGTCTTGCTTGCTCCATTGGTAGTGTCC
AATATCCAGCTGACGGCAGCGACGCTCGTAGTTTGCTACAAAATGCTGATACCGCCATGTATGAAGCAAAGGATCGAGGC
AGAAACCGTTTAATTAAATTTCATGACCAAATGAACAAAGAAGCACGCATGCGTCTTTGGTTAGAGATCGAATTACAAAA
AGCACTTCAAAATAATGGGCTTGAAGTATGGTACCAACCAAAAGTAAGTGCTCGTGATTTTAGAATTAATGGCGCAGAAG
CCCTTGTTCGATGGAAGCATCCTGTTGAAGGTTACATCAGTCCTGCTCGCTTCATCCCTGTTGCTGAACGTTCAGGTCTA
ATTGAAACACTAGGCAAAGTTGTGATGCGTGAGGTTTTCCAAACCGTTAAGGAATGGAAGAATCAAGGGATTTTACCTGG
TCGTATTGCCATTAACTTATCCCCAGAGCAATTTGGTAATCCTCAATTAATTGAGTACATGGAACGACTTCTTAAAACGA
CACAAGTTGATCCTAACTGTATCACGTTAGAATTAACTGAAAGTGCGGTAATGAGTGATGGCGAGCACGCTATCCAAATG
TTAGATGCAATAAAGAAGCTTGGTTTTACCTTATCAATTGATGACTTTGGTACGGGTTACTCTTCTTTAGCTTATCTTGC
TCGCTTCCCATTAGATGAGTTAAAAATCGATCGTGGGTTTATTAATGAAATCGACACATTACCTAAGCAAATTACGATCA
TAGAAAACGTAATTAATTTAGGTAAAAATTTAAACATGGATATCGTTGCTGAAGGTGTCGAAACAAGACAACAAGCAATG
CTATTATCAAGCCTAAATTGTGATTCCATTCAAGGGTTCCATTTCTACAAACCTCAACCAAAACATGAGATTGAAGCGTT
ATTAGTACAAAACAAACGCGCTAGATAA

Upstream 100 bases:

>100_bases
GAAAATAGGGATTCTTTCAATGTATATTTTACTGTTCGTCTTATAAATAAACATTATATCTCTGGAAGTTATTGGTCTTC
TTTACTAAAGCGGTAACACT

Downstream 100 bases:

>100_bases
ATAGAAATAATCGAACTTAATACCTAGATAAAACCCACCACTTTCTAGGTATTACAGTCGATTATAAATTTAAAAAGAGC
AAAAACTCAGGTTGAACCTC

Product: modulator of RNase II stability

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MSLSQIQHWLPLLTDNSPFLFAILDKDHKYITVNNRYCELSGLNRESLCGRSDSEILGKHFYSSLKAYYDRALNGEKIEA
EITLDDHRFDTSLHFSLFPIHEEDTTYIVFHAVDTSERQQLLNSLKESESKYHKLTELLSDSVFLIEGDIIVSANGASAK
MLGFNNPTEFIGESIEQLLHSPSRTQCLSELISSLPSEQQLTVRTTANCSLRAELILTVEETHILGSPAHLVILKENKKQ
IAMSNHIAASQVDLLTGIYNRHGFTHVIEKMIKEDIPFFMLYLDIDNFKNINDSLGHHIGDRVLKEISNRLQKLLPKHAV
VGHLGGDEFGILFPKPEHNQVLEQLSEKIISLINQPFDLVHFSKRLACSIGSVQYPADGSDARSLLQNADTAMYEAKDRG
RNRLIKFHDQMNKEARMRLWLEIELQKALQNNGLEVWYQPKVSARDFRINGAEALVRWKHPVEGYISPARFIPVAERSGL
IETLGKVVMREVFQTVKEWKNQGILPGRIAINLSPEQFGNPQLIEYMERLLKTTQVDPNCITLELTESAVMSDGEHAIQM
LDAIKKLGFTLSIDDFGTGYSSLAYLARFPLDELKIDRGFINEIDTLPKQITIIENVINLGKNLNMDIVAEGVETRQQAM
LLSSLNCDSIQGFHFYKPQPKHEIEALLVQNKRAR

Sequences:

>Translated_675_residues
MSLSQIQHWLPLLTDNSPFLFAILDKDHKYITVNNRYCELSGLNRESLCGRSDSEILGKHFYSSLKAYYDRALNGEKIEA
EITLDDHRFDTSLHFSLFPIHEEDTTYIVFHAVDTSERQQLLNSLKESESKYHKLTELLSDSVFLIEGDIIVSANGASAK
MLGFNNPTEFIGESIEQLLHSPSRTQCLSELISSLPSEQQLTVRTTANCSLRAELILTVEETHILGSPAHLVILKENKKQ
IAMSNHIAASQVDLLTGIYNRHGFTHVIEKMIKEDIPFFMLYLDIDNFKNINDSLGHHIGDRVLKEISNRLQKLLPKHAV
VGHLGGDEFGILFPKPEHNQVLEQLSEKIISLINQPFDLVHFSKRLACSIGSVQYPADGSDARSLLQNADTAMYEAKDRG
RNRLIKFHDQMNKEARMRLWLEIELQKALQNNGLEVWYQPKVSARDFRINGAEALVRWKHPVEGYISPARFIPVAERSGL
IETLGKVVMREVFQTVKEWKNQGILPGRIAINLSPEQFGNPQLIEYMERLLKTTQVDPNCITLELTESAVMSDGEHAIQM
LDAIKKLGFTLSIDDFGTGYSSLAYLARFPLDELKIDRGFINEIDTLPKQITIIENVINLGKNLNMDIVAEGVETRQQAM
LLSSLNCDSIQGFHFYKPQPKHEIEALLVQNKRAR
>Mature_674_residues
SLSQIQHWLPLLTDNSPFLFAILDKDHKYITVNNRYCELSGLNRESLCGRSDSEILGKHFYSSLKAYYDRALNGEKIEAE
ITLDDHRFDTSLHFSLFPIHEEDTTYIVFHAVDTSERQQLLNSLKESESKYHKLTELLSDSVFLIEGDIIVSANGASAKM
LGFNNPTEFIGESIEQLLHSPSRTQCLSELISSLPSEQQLTVRTTANCSLRAELILTVEETHILGSPAHLVILKENKKQI
AMSNHIAASQVDLLTGIYNRHGFTHVIEKMIKEDIPFFMLYLDIDNFKNINDSLGHHIGDRVLKEISNRLQKLLPKHAVV
GHLGGDEFGILFPKPEHNQVLEQLSEKIISLINQPFDLVHFSKRLACSIGSVQYPADGSDARSLLQNADTAMYEAKDRGR
NRLIKFHDQMNKEARMRLWLEIELQKALQNNGLEVWYQPKVSARDFRINGAEALVRWKHPVEGYISPARFIPVAERSGLI
ETLGKVVMREVFQTVKEWKNQGILPGRIAINLSPEQFGNPQLIEYMERLLKTTQVDPNCITLELTESAVMSDGEHAIQML
DAIKKLGFTLSIDDFGTGYSSLAYLARFPLDELKIDRGFINEIDTLPKQITIIENVINLGKNLNMDIVAEGVETRQQAML
LSSLNCDSIQGFHFYKPQPKHEIEALLVQNKRAR

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=418, Percent_Identity=35.4066985645933, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI87081921, Length=418, Percent_Identity=30.8612440191388, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI226510982, Length=408, Percent_Identity=26.9607843137255, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=38.2352941176471, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788502, Length=237, Percent_Identity=36.7088607594937, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=35.4166666666667, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1786507, Length=235, Percent_Identity=34.0425531914894, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=33.7552742616034, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1787055, Length=313, Percent_Identity=28.7539936102236, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI87081980, Length=255, Percent_Identity=32.156862745098, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788849, Length=251, Percent_Identity=32.2709163346614, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87082096, Length=208, Percent_Identity=30.7692307692308, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1787802, Length=172, Percent_Identity=31.9767441860465, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693134, Length=333, Percent_Identity=26.4264264264264, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=29.375, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788381, Length=317, Percent_Identity=24.9211356466877, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=33.5443037974684, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788085, Length=160, Percent_Identity=30, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1786584, Length=183, Percent_Identity=30.6010928961749, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87081881, Length=279, Percent_Identity=27.9569892473118, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082007, Length=160, Percent_Identity=32.5, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1787410, Length=152, Percent_Identity=30.2631578947368, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789650, Length=425, Percent_Identity=18.8235294117647, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87081977, Length=156, Percent_Identity=34.6153846153846, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=217, Percent_Identity=28.110599078341, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 76642; Mature: 76511

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSQIQHWLPLLTDNSPFLFAILDKDHKYITVNNRYCELSGLNRESLCGRSDSEILGKH
CCHHHHHHHHHHEECCCCEEEEEEECCCCEEEECCCEEEECCCCHHHHCCCCCHHHHHHH
FYSSLKAYYDRALNGEKIEAEITLDDHRFDTSLHFSLFPIHEEDTTYIVFHAVDTSERQQ
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEEEEECCCCEEEEEEECCCHHHHH
LLNSLKESESKYHKLTELLSDSVFLIEGDIIVSANGASAKMLGFNNPTEFIGESIEQLLH
HHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCEEEECCCCCHHHHHHHHHHHHC
SPSRTQCLSELISSLPSEQQLTVRTTANCSLRAELILTVEETHILGSPAHLVILKENKKQ
CCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEEEHHEEECCCEEEEEEECCCCH
IAMSNHIAASQVDLLTGIYNRHGFTHVIEKMIKEDIPFFMLYLDIDNFKNINDSLGHHIG
HHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHH
DRVLKEISNRLQKLLPKHAVVGHLGGDEFGILFPKPEHNQVLEQLSEKIISLINQPFDLV
HHHHHHHHHHHHHHCCHHHEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHH
HFSKRLACSIGSVQYPADGSDARSLLQNADTAMYEAKDRGRNRLIKFHDQMNKEARMRLW
HHHHHHHHCCCCEECCCCCHHHHHHHHCCCHHHHHHHHCCCHHEEHHHHHCCCCCCEEEE
LEIELQKALQNNGLEVWYQPKVSARDFRINGAEALVRWKHPVEGYISPARFIPVAERSGL
EEEEHHHHHHCCCCEEEECCCCCCCEEEECCHHHHEEECCCCCCCCCCHHEEECHHCCCH
IETLGKVVMREVFQTVKEWKNQGILPGRIAINLSPEQFGNPQLIEYMERLLKTTQVDPNC
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCHHHHHHHHHHHHCCCCCCE
ITLELTESAVMSDGEHAIQMLDAIKKLGFTLSIDDFGTGYSSLAYLARFPLDELKIDRGF
EEEEEEHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHCCCHH
INEIDTLPKQITIIENVINLGKNLNMDIVAEGVETRQQAMLLSSLNCDSIQGFHFYKPQP
HHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCHHHHHHHHHHHCCCCCCCCCEECCCCCC
KHEIEALLVQNKRAR
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLSQIQHWLPLLTDNSPFLFAILDKDHKYITVNNRYCELSGLNRESLCGRSDSEILGKH
CHHHHHHHHHHEECCCCEEEEEEECCCCEEEECCCEEEECCCCHHHHCCCCCHHHHHHH
FYSSLKAYYDRALNGEKIEAEITLDDHRFDTSLHFSLFPIHEEDTTYIVFHAVDTSERQQ
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEEEEECCCCEEEEEEECCCHHHHH
LLNSLKESESKYHKLTELLSDSVFLIEGDIIVSANGASAKMLGFNNPTEFIGESIEQLLH
HHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCEEEECCCCCHHHHHHHHHHHHC
SPSRTQCLSELISSLPSEQQLTVRTTANCSLRAELILTVEETHILGSPAHLVILKENKKQ
CCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEEEHHEEECCCEEEEEEECCCCH
IAMSNHIAASQVDLLTGIYNRHGFTHVIEKMIKEDIPFFMLYLDIDNFKNINDSLGHHIG
HHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHH
DRVLKEISNRLQKLLPKHAVVGHLGGDEFGILFPKPEHNQVLEQLSEKIISLINQPFDLV
HHHHHHHHHHHHHHCCHHHEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHH
HFSKRLACSIGSVQYPADGSDARSLLQNADTAMYEAKDRGRNRLIKFHDQMNKEARMRLW
HHHHHHHHCCCCEECCCCCHHHHHHHHCCCHHHHHHHHCCCHHEEHHHHHCCCCCCEEEE
LEIELQKALQNNGLEVWYQPKVSARDFRINGAEALVRWKHPVEGYISPARFIPVAERSGL
EEEEHHHHHHCCCCEEEECCCCCCCEEEECCHHHHEEECCCCCCCCCCHHEEECHHCCCH
IETLGKVVMREVFQTVKEWKNQGILPGRIAINLSPEQFGNPQLIEYMERLLKTTQVDPNC
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCHHHHHHHHHHHHCCCCCCE
ITLELTESAVMSDGEHAIQMLDAIKKLGFTLSIDDFGTGYSSLAYLARFPLDELKIDRGF
EEEEEEHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHCCCHH
INEIDTLPKQITIIENVINLGKNLNMDIVAEGVETRQQAMLLSSLNCDSIQGFHFYKPQP
HHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCHHHHHHHHHHHCCCCCCCCCEECCCCCC
KHEIEALLVQNKRAR
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]