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The map label for this gene is manA2 [H]

Identifier: 57652382

GI number: 57652382

Start: 2728203

End: 2729141

Strand: Direct

Name: manA2 [H]

Synonym: SACOL2664

Alternate gene names: 57652382

Gene position: 2728203-2729141 (Clockwise)

Preceding gene: 57652381

Following gene: 57652384

Centisome position: 97.11

GC content: 35.57

Gene sequence:

>939_bases
ATGGCATTATTTTTACAACCCGTTTTTAAAGACAGAATTTGGGGCGGTCATGCATTAAAAGCATTTAACTATGATATCCC
TAATGAAACAACTGGTGAATGCTGGGCAATTTCTGCACATCCAAATGGTCCTAATACAATTATCAATGGTCCATACAAGG
ATATGACCCTAGATCAACTTTGGTCACAACATCGTGAATTATTCGATAATGATTCACGAGATAGTTTCCCTCTGCTAACT
AAAGTATTAGATGCCAATGATAAATTATCTGTTCAAGTTCACCCAGATGATGACTACGCTTTAAAACACGAAGGCGAACT
AGGTAAAACAGAATGTTGGTATATTTTAGATGCAGCCCCAGGTGCTGAAATTATATATGGCGTACATGCACATAATAAAC
AGACGTTAATAGACATGATTGATAATCATGAATTTGACAGTCTTTTCAAACGTATACCTGTTAAGCCCGGTGACTTTTAT
TATGTTCCTGCTGGCACTGTCCATGCCATTGGTTCGGGTATTTTAATTTTAGAGACACAACAATCCTCCGATACGACATA
CCGTATTTATGACTATGATAGACGAGATCAAAATGGTCAATTGCGTGATTTGCACTTAGAGCAAAGTAAAGATGTGATTG
AATTAGGCAATCATGAACCAAATACTACTCCTATAACAACTCACATCGACACACACACTGTAACTCAATTTGTAGATAAT
CAATATTTTGCAGTATATAAATGGGATATTCATGGAGATTTAAAATTCAATAAACCACATGCTTATTGCTTAGTTACAAT
TATCGATGGTACTGGTACTTTAACAGTAAACGATAAGCACTATGACATCCAAAAAGGTTCTAGCTTTATTTTAACTACGG
AAGACGAGGATATTCACTTTGTCGGTAATATTAGTGCTATAGTAAGTCATCCTGGATAA

Upstream 100 bases:

>100_bases
AAAGCGTTAATGAATGATGAGACACGCCAATCACTAATTAATGCAAACAGTACTACAGAAATTTATAACTTATTAATGAA
AATATAGAGGAGTTTTAACT

Downstream 100 bases:

>100_bases
TAGCAATGATAACAACCGTCCCATAAAAGACAGAAATTACTATCTCTTCTGTCTAAAAACATAAAAATCCACACATTAAG
GAGCTATAACCCTAATGTGT

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MALFLQPVFKDRIWGGHALKAFNYDIPNETTGECWAISAHPNGPNTIINGPYKDMTLDQLWSQHRELFDNDSRDSFPLLT
KVLDANDKLSVQVHPDDDYALKHEGELGKTECWYILDAAPGAEIIYGVHAHNKQTLIDMIDNHEFDSLFKRIPVKPGDFY
YVPAGTVHAIGSGILILETQQSSDTTYRIYDYDRRDQNGQLRDLHLEQSKDVIELGNHEPNTTPITTHIDTHTVTQFVDN
QYFAVYKWDIHGDLKFNKPHAYCLVTIIDGTGTLTVNDKHYDIQKGSSFILTTEDEDIHFVGNISAIVSHPG

Sequences:

>Translated_312_residues
MALFLQPVFKDRIWGGHALKAFNYDIPNETTGECWAISAHPNGPNTIINGPYKDMTLDQLWSQHRELFDNDSRDSFPLLT
KVLDANDKLSVQVHPDDDYALKHEGELGKTECWYILDAAPGAEIIYGVHAHNKQTLIDMIDNHEFDSLFKRIPVKPGDFY
YVPAGTVHAIGSGILILETQQSSDTTYRIYDYDRRDQNGQLRDLHLEQSKDVIELGNHEPNTTPITTHIDTHTVTQFVDN
QYFAVYKWDIHGDLKFNKPHAYCLVTIIDGTGTLTVNDKHYDIQKGSSFILTTEDEDIHFVGNISAIVSHPG
>Mature_311_residues
ALFLQPVFKDRIWGGHALKAFNYDIPNETTGECWAISAHPNGPNTIINGPYKDMTLDQLWSQHRELFDNDSRDSFPLLTK
VLDANDKLSVQVHPDDDYALKHEGELGKTECWYILDAAPGAEIIYGVHAHNKQTLIDMIDNHEFDSLFKRIPVKPGDFYY
VPAGTVHAIGSGILILETQQSSDTTYRIYDYDRRDQNGQLRDLHLEQSKDVIELGNHEPNTTPITTHIDTHTVTQFVDNQ
YFAVYKWDIHGDLKFNKPHAYCLVTIIDGTGTLTVNDKHYDIQKGSSFILTTEDEDIHFVGNISAIVSHPG

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 35396; Mature: 35265

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFLQPVFKDRIWGGHALKAFNYDIPNETTGECWAISAHPNGPNTIINGPYKDMTLDQL
CEEEECCHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEECCCCCCCCHHHH
WSQHRELFDNDSRDSFPLLTKVLDANDKLSVQVHPDDDYALKHEGELGKTECWYILDAAP
HHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCC
GAEIIYGVHAHNKQTLIDMIDNHEFDSLFKRIPVKPGDFYYVPAGTVHAIGSGILILETQ
CCEEEEEEECCCCCEEEHHHCCCCHHHHHHHCCCCCCCEEEECCCHHHHCCCCEEEEEEC
QSSDTTYRIYDYDRRDQNGQLRDLHLEQSKDVIELGNHEPNTTPITTHIDTHTVTQFVDN
CCCCCEEEEEEECCCCCCCCEEEEEECCCCCCEECCCCCCCCCCEEEECCHHHHHHHHCC
QYFAVYKWDIHGDLKFNKPHAYCLVTIIDGTGTLTVNDKHYDIQKGSSFILTTEDEDIHF
CEEEEEEEEEEEEEEECCCCEEEEEEEECCCEEEEECCCEEEECCCCEEEEEECCCCEEE
VGNISAIVSHPG
EEEEEEEEECCC
>Mature Secondary Structure 
ALFLQPVFKDRIWGGHALKAFNYDIPNETTGECWAISAHPNGPNTIINGPYKDMTLDQL
EEEECCHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEECCCCCCCCHHHH
WSQHRELFDNDSRDSFPLLTKVLDANDKLSVQVHPDDDYALKHEGELGKTECWYILDAAP
HHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCC
GAEIIYGVHAHNKQTLIDMIDNHEFDSLFKRIPVKPGDFYYVPAGTVHAIGSGILILETQ
CCEEEEEEECCCCCEEEHHHCCCCHHHHHHHCCCCCCCEEEECCCHHHHCCCCEEEEEEC
QSSDTTYRIYDYDRRDQNGQLRDLHLEQSKDVIELGNHEPNTTPITTHIDTHTVTQFVDN
CCCCCEEEEEEECCCCCCCCEEEEEECCCCCCEECCCCCCCCCCEEEECCHHHHHHHHCC
QYFAVYKWDIHGDLKFNKPHAYCLVTIIDGTGTLTVNDKHYDIQKGSSFILTTEDEDIHF
CEEEEEEEEEEEEEEECCCCEEEEEEEECCCEEEEECCCEEEECCCCEEEEEECCCCEEE
VGNISAIVSHPG
EEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8293960; 12397186 [H]