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The map label for this gene is manA1 [H]

Identifier: 57652165

GI number: 57652165

Start: 2196092

End: 2197030

Strand: Reverse

Name: manA1 [H]

Synonym: SACOL2135

Alternate gene names: 57652165

Gene position: 2197030-2196092 (Counterclockwise)

Preceding gene: 57652166

Following gene: 57652164

Centisome position: 78.2

GC content: 34.72

Gene sequence:

>939_bases
ATGCCATTATTTTTACAACCAATTTTAAAAACAAAATTATGGGGCGGTCAACGTCTAAGTGAGTTTGGATATCAATTAGA
CAATGATACAACTGGGGAATGTTGGTGTGTGTCAGCACATCCAAATGGTACGAGCGAGATTATTAATGGACCATATCAAG
GTCAAACATTAGACCGTATTTGGTCAGAACATCGTGAATTGTTTGGTGATTTCCCAAGCAAAGATTTTCCGCTTCTAACT
AAAATAGTGGATGCAAGAGAATCACTTTCTATTCATGTGCACCCTGATAATTCTTATGCTTATGAGCATGAAAACGGGCA
ATATGGCAAATCTGAATGTTGGTATATTATAGATGCAGAAGAAGATGCAGAAATAGTTATAGGGACATTAGCAGAGTCTA
GAGAAGAAGTTGCGAATCATGTTCAACACGGAACGATAGAGTCGATACTTAGATATATTAAAGTAAAACCTGGAGAATTC
TATTTTATTCCAGCAGGAACAGTACATACTATTTCTTCAGGAATATTAGCATACGAAACGATGCAATCGTCAGACATTAC
ATATAGACTTTATGATTTCAATCGTCAAGATAATCAATATAATGATAGACCGTTAAATATTGAAAAAGCTTTAGACGTTA
TTCAGTACAATGCACCATTACCTAATATTTTGCCTGAAAGCGAAATTATTGAAAACCATAAGTGTACACACATTGTATCG
AATGATTTCTTTACATTGGTTAAATGGGAAATTTCTGGCACGTTAAATTATATGAAGCCTAGAGAGTTCTGTTTAGTTAC
AGTGTTGGAAGGCGAAGGGCAAATGATTGTCGATGGTGAAATTTTCAAACTGACTACTGGTACAAACTTTATTTTGACTT
CTGAAGATTTGGATAGTGTCTTTGAAGGTGATTTCACATTGATGATTAGCTATGTGTAA

Upstream 100 bases:

>100_bases
GGAAGTTAATAATACGATGTAAATGAGAACAAAATCAAAATATAATGGAACAACAACATCAGAGTTCTATTGCTTACTTA
ATCACAATGGAGGTGCAACA

Downstream 100 bases:

>100_bases
TAGTGTAATAACAATTTAGGAGTGAATGATTTGAAGCAATTTCTATATATTGCGTTAGTATGTGGTGTGATAGCAGGTCT
TGGTGCTTTCTTACATATAC

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLT
KIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEF
YFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVS
NDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV

Sequences:

>Translated_312_residues
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLT
KIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEF
YFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVS
NDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>Mature_311_residues
PLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTK
IVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFY
FIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSN
DFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 35643; Mature: 35512

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRI
CCEEHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCHHHHH
WSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAE
HHHHHHHHCCCCCCCCHHHHHHHCCHHCCEEEEECCCCEEEECCCCCCCCCCEEEEEECC
EDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYET
CCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHCCEEEEEE
MQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVS
ECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEEEC
NDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSV
CCEEEEEEEEECCEEECCCCCCEEEEEEEECCCCEEECCEEEEEECCCEEEEECHHHHHH
FEGDFTLMISYV
HCCCEEEEEEEC
>Mature Secondary Structure 
PLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRI
CEEHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCHHHHH
WSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAE
HHHHHHHHCCCCCCCCHHHHHHHCCHHCCEEEEECCCCEEEECCCCCCCCCCEEEEEECC
EDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYET
CCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHCCEEEEEE
MQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVS
ECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEEEC
NDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSV
CCEEEEEEEEECCEEECCCCCCEEEEEEEECCCCEEECCEEEEEECCCEEEEECHHHHHH
FEGDFTLMISYV
HCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8293960; 12397186 [H]