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The map label for this gene is coaW

Identifier: 57652152

GI number: 57652152

Start: 2183207

End: 2184010

Strand: Direct

Name: coaW

Synonym: SACOL2122

Alternate gene names: 57652152

Gene position: 2183207-2184010 (Clockwise)

Preceding gene: 57652148

Following gene: 57652156

Centisome position: 77.71

GC content: 37.31

Gene sequence:

>804_bases
ATGAAAGTTGGCATTGACGCTGGCGGTACACTAATTAAAATCGTTCAAGAGCAAGATAACCAACGTACTTTTAAAACTGA
ATTAACTAAAAATATTGATCAAGTTGTGGAATGGTTAAACCAACAGCAAATTGAAAAATTATGCTTAACTGGAGGTAATG
CAGGTGTCATTGCTGAAAACATCAACATTCCTGCACAAATTTTTGTAGAGTTTGATGCTGCATCTCAAGGACTAGGTATT
TTGTTAAAAGAGCAAGGCCATGACTTAGCAGATTATATTTTTGCAAATGTTGGTACCGGTACGTCACTACATTATTTCGA
CGGCCAATCACAACGTCGTGTAGGCGGTATCGGTACAGGTGGAGGCATGATTCAAGGACTCGGTTATTTACTAAGTCAAA
TCACTGATTATAAACAGTTAACTGACATGGCACAACACGGTGATCGTAACACTATCGATTTAAAGGTTAGACATATTTAT
AAAGATACCGAACCACCCATTCCCGGTGATTTAACAGCAGCTAATTTTGGTCATGTACTACATCATTTAGATGCTGATTT
TACACCTAGCAATAAATTAGCAGCCGTTATTGGTGTCGTTGGCGAAGTTGTTACGACAATGGCCATTACTGTTGCACGTG
AATTTAAAACTGAAAATATCGTTTATATCGGTTCTTCATTTCATAATAACGCTTTATTACGCAAAGTTGTGGAAGATTAT
ACTGTGTTACGCGGTTGCAAACCGTACTATGTTGAAAACGGCGCATTTTCAGGTGCTATTGGTGCATTATATTTAGAAAA
ATAG

Upstream 100 bases:

>100_bases
TGGCATCAAATTTGTTAATAATTACTATTATTACTTGTTTTTTAGTCATTTTACTATACTATTATTTAAGGATAGACATT
AATAATGAGGTGGGAATCTT

Downstream 100 bases:

>100_bases
AAAAAGACCATTTATATGCGCGTTGTTTTAAATAAACGCTATATAAATGGCCTTTTATTTTATGGTCTAAGTGTTTTGAA
TACGTATTGTTCCATTTATT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-II; Pantothenic acid kinase

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGI
LLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIY
KDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
TVLRGCKPYYVENGAFSGAIGALYLEK

Sequences:

>Translated_267_residues
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGI
LLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIY
KDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
TVLRGCKPYYVENGAFSGAIGALYLEK
>Mature_267_residues
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGI
LLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIY
KDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
TVLRGCKPYYVENGAFSGAIGALYLEK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG5146

COG function: function code H; Pantothenate kinase, acetyl-CoA regulated

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type II pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAW_STAA3 (Q2FEZ8)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494730.1
- ProteinModelPortal:   Q2FEZ8
- SMR:   Q2FEZ8
- DIP:   DIP-29151N
- STRING:   Q2FEZ8
- EnsemblBacteria:   EBSTAT00000036337
- GeneID:   3914037
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_2084
- eggNOG:   COG5146
- GeneTree:   EBGT00050000023914
- HOGENOM:   HBG339744
- OMA:   LTASNFG
- ProtClustDB:   PRK13317
- GO:   GO:0005737
- HAMAP:   MF_01273
- InterPro:   IPR011602
- InterPro:   IPR014642
- InterPro:   IPR004567
- PANTHER:   PTHR12280:SF4
- TIGRFAMs:   TIGR00555

Pfam domain/function: PF03630 Fumble

EC number: =2.7.1.33

Molecular weight: Translated: 29097; Mature: 29097

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: ACT_SITE 70-70 BINDING 99-99 BINDING 137-137 BINDING 225-225

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAEN
CEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
INIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTG
CCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
GGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHH
HHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
TVLRGCKPYYVENGAFSGAIGALYLEK
HHHHCCCCEEEECCCCCCCEEEEEECC
>Mature Secondary Structure
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAEN
CEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
INIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTG
CCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
GGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHH
HHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
TVLRGCKPYYVENGAFSGAIGALYLEK
HHHHCCCCEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA