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The map label for this gene is ptpB

Identifier: 57652137

GI number: 57652137

Start: 2167486

End: 2167905

Strand: Reverse

Name: ptpB

Synonym: SACOL2107

Alternate gene names: 57652137

Gene position: 2167905-2167486 (Counterclockwise)

Preceding gene: 57652138

Following gene: 57652136

Centisome position: 77.17

GC content: 32.86

Gene sequence:

>420_bases
ATGAAGATTTTATTCGTTTGTACAGGTAACACATGTCGTAGCCCATTAGCGGAAAGTATTGCAAAAGAGGTTATGCCAAA
TCATCAATTTGAATCAAGAGGTATATTCGCTGTGAACAATCAAGGTGTTTCGAATTATGTTGAAGACTTAGTTGAAGAAC
ATCATTTAGCTGAAACGACCTTATCGCAACAATTTACTGAAGCAGATTTGAAAGCAGATATTATTTTGACGATGTCGTAT
TCGCACAAAGAATTAATAGAGGCACACTTTGGTTTGCAAAATCATGTTTTCACATTGCATGAATATGTAAAAGAAGCAGG
AGAAGTTATAGATCCATACGGTGGAACAAAAGAAATGTATGTACATACCTATGAAGAACTTGTAAGTTTAATTTTAAAAT
TAAAAGATATTATTTGCTAG

Upstream 100 bases:

>100_bases
CGGCGTATATATACGGCTTTGAGCTGAATGATAATACAGAAGCAATTATGAATCGCATGTTAAAAGCTGCAGGTAATCAC
ATTATTAAAGGATGTGAACT

Downstream 100 bases:

>100_bases
TAGGAATTCTGTATAATTAGTATATGTTAACAGTTAAATAAGTTATAATAGAGGAGTGTAGCACTTTGCTATATTCCTTT
TTTATTTTTAGGAAGGGTGG

Product: phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: Phosphotyrosine phosphatase B; PTPase B

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSY
SHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC

Sequences:

>Translated_139_residues
MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSY
SHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC
>Mature_139_residues
MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSY
SHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC

Specific function: Dephosphorylates the phosphotyrosine-containing proteins

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTPB_STAA3 (Q2FF13)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494715.1
- HSSP:   P39155
- ProteinModelPortal:   Q2FF13
- STRING:   Q2FF13
- EnsemblBacteria:   EBSTAT00000038497
- GeneID:   3914055
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_2069
- eggNOG:   COG0394
- GeneTree:   EBGT00050000025092
- HOGENOM:   HBG730979
- OMA:   KSAYLEI
- ProtClustDB:   CLSK885771
- InterPro:   IPR000106
- InterPro:   IPR017867
- PANTHER:   PTHR11717
- PRINTS:   PR00719
- SMART:   SM00226

Pfam domain/function: PF01451 LMWPc; SSF52788 Tyr_Pase_low_mol_wt

EC number: =3.1.3.48

Molecular weight: Translated: 15788; Mature: 15788

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: ACT_SITE 7-7 ACT_SITE 13-13 ACT_SITE 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETT
CEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
LSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMY
HHHHHHHHCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VHTYEELVSLILKLKDIIC
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETT
CEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
LSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMY
HHHHHHHHCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VHTYEELVSLILKLKDIIC
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA