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The map label for this gene is atpB

Identifier: 57652131

GI number: 57652131

Start: 2162513

End: 2163241

Strand: Reverse

Name: atpB

Synonym: SACOL2101

Alternate gene names: 57652131

Gene position: 2163241-2162513 (Counterclockwise)

Preceding gene: 57652132

Following gene: 57652130

Centisome position: 77.0

GC content: 35.53

Gene sequence:

>729_bases
ATGGATCACAAATCCCCGCTCGTGAGTTGGAATTTATTCGGTTTTGATATCGTTTTCAATTTATCAAGTATATTGATGAT
ACTTGTTACGGCGTTTCTTGTTTTTCTACTTGCTATCATTTGTACGCGTAATTTGAAAAAAAGACCAACTGGCAAACAAA
ATTTCGTTGAATGGATTTTTGATTTCGTGAGGGGAATCATTGAAGGTAACATGGCTTGGAAAAAAGGTGGTCAATTCCAC
TTCTTAGCAGTAACGCTGATTCTGTACATTTTTATAGCTAATATGTTAGGTCTTCCGTTTTCTATAGTAACGAAAGATCA
CACATTGTGGTGGAAATCACCGACAGCTGATGCAACAGTGACTTTAACGTTGTCTACAACGATAATACTGTTAACTCACT
TTTATGGAATTAAAATGCGTGGTACGAAACAATATCTTAAAGGTTATGTACAGCCGTTTTGGCCATTGGCAATTATTAAT
GTTTTTGAAGAGTTCACTTCAACATTAACGCTTGGTCTGCGTTTGTACGGTAACATATTTGCAGGTGAGATACTATTAAC
ATTACTTGCTGGCTTATTCTTTAACGAACCAGCATGGGGTTGGATTATTAGTATCCCAGGATTAATTGTTTGGCAAGCAT
TTTCAATATTTGTAGGAACAATCCAAGCATATATCTTTATTATGCTTTCGATGGTTTATATGTCACATAAAGTGGCAGAT
GAACACTAA

Upstream 100 bases:

>100_bases
GTATCATCGGTATAATTATTGGTTTAATGATTTCATATGTTGTAGTTATCATACGTCCTTTACTAAAGGTGAGCAAATAA
ATTAAGAAAGAGGTGAGATT

Downstream 100 bases:

>100_bases
AAATTTCAATAATTATATACAATCACAGGAGGAAATTAAATTATGAATTTAATCGCAGCAGCAATCGCAATTGGTTTATC
AGCATTAGGAGCAGGTATCG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFH
FLAVTLILYIFIANMLGLPFSIVTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIIN
VFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVAD
EH

Sequences:

>Translated_242_residues
MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFH
FLAVTLILYIFIANMLGLPFSIVTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIIN
VFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVAD
EH
>Mature_242_residues
MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFH
FLAVTLILYIFIANMLGLPFSIVTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIIN
VFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVAD
EH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=220, Percent_Identity=34.5454545454545, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_STAA1 (A7X4V1)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442683.1
- ProteinModelPortal:   A7X4V1
- SMR:   A7X4V1
- STRING:   A7X4V1
- EnsemblBacteria:   EBSTAT00000004217
- GeneID:   5559737
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2093
- eggNOG:   COG0356
- GeneTree:   EBGT00050000025099
- HOGENOM:   HBG734175
- OMA:   LHGQVFL
- ProtClustDB:   PRK05815
- BioCyc:   SAUR418127:SAHV_2093-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 27630; Mature: 27630

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf9166b0)-; HASH(0xbac74a4)-; HASH(0xbb19b7c)-; HASH(0xfe1fa74)-; HASH(0xf8e6f74)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIF
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
DFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSIVTKDHTLWWKSPTADATV
HHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCEEE
TLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIINVFEEFTSTLTLGLRLYGNIF
EEEHHHHHHHHHHHHCCEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVAD
HHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EH
CH
>Mature Secondary Structure
MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIF
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
DFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSIVTKDHTLWWKSPTADATV
HHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCEEE
TLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIINVFEEFTSTLTLGLRLYGNIF
EEEHHHHHHHHHHHHCCEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVAD
HHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EH
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA