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The map label for this gene is atpA [H]

Identifier: 57652127

GI number: 57652127

Start: 2159470

End: 2160978

Strand: Reverse

Name: atpA [H]

Synonym: SACOL2097

Alternate gene names: 57652127

Gene position: 2160978-2159470 (Counterclockwise)

Preceding gene: 57652128

Following gene: 57652126

Centisome position: 76.92

GC content: 36.98

Gene sequence:

>1509_bases
ATGGCCATAAAAGCTGAAGAAATCAGTGCATTACTTCGCTCACAAATTGAAAATTATGAGTCAGAAATGTCCGTAACTGA
TGTAGGTACTGTATTACAAATTGGTGATGGTATTGCATTAATTCACGGATTAAATGACGTTATGGCTGGTGAGCTAGTAG
AATTCCATAACGGCGTACTTGGTTTAGCCCAAAACCTTGAAGAGTCAAACGTGGGTGTGGTTATTTTAGGACCATACACA
GGTATTACTGAAGGTGACGAAGTTAAACGTACTGGTCGTATCATGGAAGTACCAGTAGGTGAAGAACTAATCGGAAGAGT
TGTTAATCCATTAGGACAACCTATTGATGGACAAGGACCGATTAACACAACTAAAACACGTCCAGTAGAGAAAAAAGCTA
CTGGTGTAATGGATCGTAAATCAGTAGATGAGCCATTACAAACAGGTATCAAAGCAATTGATGCTTTAGTACCAATTGGT
AGAGGTCAACGTGAGTTAATCATCGGTGACCGTCAAACAGGTAAAACAACAATTGCAATTGACACAATTTTGAACCAAAA
AGATCAAGGTACGATTTGTATCTATGTTGCTATTGGTCAAAAAGATTCAACAGTAAGAGCAAATGTTGAAAAGTTAAGAC
AAGCAGGCGCTTTAGACTACACTATTGTTGTAGCAGCATCAGCTTCTGAACCTTCTCCATTATTATATATTGCACCATAT
TCAGGTGTAACAATGGGTGAAGAATTCATGTTTAACGGTAAACATGTTTTAATCGTTTATGATGATTTAACTAAACAAGC
AGCAGCTTATCGTGAGTTATCATTATTATTACGTAGACCTCCAGGTCGTGAAGCATACCCAGGTGACGTATTCTACTTAC
ATAGTAGATTATTAGAAAGAGCAGCAAAATTAAACGATGACTTAGGTGGCGGTTCAATTACTGCATTACCAATTATCGAA
ACACAAGCTGGTGATATTTCAGCTTATGTACCAACAAACGTTATTTCAATTACAGATGGACAAATCTTCTTACAATCTGA
TTTATTCTTCTCAGGTGTAAGACCAGCGATTAATGCCGGACAATCTGTATCTCGTGTTGGTGGATCTGCACAAATTAATG
CAATGAAGAAAGTTGCTGGTACGTTACGTCTTGACTTAGCGTCATACAGAGAACTTGAATCATTTGCACAATTCGGTTCA
GACCTTGATGAATTTACTGCAAGTAAATTAGAACGTGGTAAACGTACTGTTGAAGTCTTAAAACAAGATCAAAACAAACC
ATTACCAGTCGAACACCAAGTGTTGATTATTTATGCATTAACAAAAGGATATTTAGATGATATTCCAGTTGTAGATATCA
CACGTTTTGAAGACGAGTTAAACCACTGGGCAGAATCAAATGCTACTGAACTGTTAAATGAAATCAGAGAAACTGGTGGC
TTACCAGATGCTGAGAAGTTTGACACAGCAATTAACGAATTCAAAAAAAGCTTTAGCAAATCTGAATAA

Upstream 100 bases:

>100_bases
AGTCGGCACAACTGTATTAGATGGTAGTGTTAGAAATGATCTTGTCCAATTACAAAGAAAATTTAGAAGAGTTAATTAAT
TATAAAGAGGAGTGACATAG

Downstream 100 bases:

>100_bases
TAAACAAGTTTAGTATAAGGTGGTGAGATAGTGGCTTCTCTTAAAGAAATAGATACTCGAATAAAATCAACCAAAAAAAT
GAAGCAGATTACGAAAGCGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYT
GITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIG
RGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPY
SGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIE
TQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQINAMKKVAGTLRLDLASYRELESFAQFGS
DLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGG
LPDAEKFDTAINEFKKSFSKSE

Sequences:

>Translated_502_residues
MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYT
GITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIG
RGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPY
SGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIE
TQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQINAMKKVAGTLRLDLASYRELESFAQFGS
DLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGG
LPDAEKFDTAINEFKKSFSKSE
>Mature_501_residues
AIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYTG
ITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGR
GQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPYS
GVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIET
QAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQINAMKKVAGTLRLDLASYRELESFAQFGSD
LDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGGL
PDAEKFDTAINEFKKSFSKSE

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=500, Percent_Identity=59.8, Blast_Score=592, Evalue=1e-169,
Organism=Homo sapiens, GI4757810, Length=500, Percent_Identity=59.8, Blast_Score=592, Evalue=1e-169,
Organism=Homo sapiens, GI19913428, Length=300, Percent_Identity=29.3333333333333, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913426, Length=295, Percent_Identity=29.8305084745763, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI32189394, Length=416, Percent_Identity=25.7211538461538, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI19913424, Length=228, Percent_Identity=28.5087719298246, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1790172, Length=512, Percent_Identity=53.3203125, Blast_Score=546, Evalue=1e-157,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=31.6176470588235, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790170, Length=318, Percent_Identity=26.4150943396226, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=503, Percent_Identity=59.8409542743539, Blast_Score=591, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI71988080, Length=503, Percent_Identity=59.8409542743539, Blast_Score=590, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI71988074, Length=503, Percent_Identity=55.8648111332008, Blast_Score=540, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17510931, Length=371, Percent_Identity=28.8409703504043, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17570191, Length=291, Percent_Identity=28.5223367697594, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=414, Percent_Identity=24.8792270531401, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=60.7843137254902, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=71, Percent_Identity=45.0704225352113, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=483, Percent_Identity=58.7991718426501, Blast_Score=573, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6322581, Length=411, Percent_Identity=26.0340632603406, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319603, Length=307, Percent_Identity=28.9902280130293, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=56.8316831683168, Blast_Score=574, Evalue=1e-164,
Organism=Drosophila melanogaster, GI281361666, Length=294, Percent_Identity=28.9115646258503, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24646341, Length=294, Percent_Identity=28.9115646258503, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17136796, Length=294, Percent_Identity=28.9115646258503, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24638766, Length=418, Percent_Identity=26.7942583732057, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574560, Length=420, Percent_Identity=26.4285714285714, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129479, Length=259, Percent_Identity=28.1853281853282, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54571; Mature: 54440

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVL
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCHH
GLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGP
HHHHCCCCCCCCEEEECCCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
INTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAI
CCCCCCCCCHHHHHCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPY
EHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCC
SGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCCCHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAG
HHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEECCCHHCCCCHHHCCC
QSVSRVGGSAQINAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTASKLERGKRTVEVL
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGG
HHCCCCCCCCCCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LPDAEKFDTAINEFKKSFSKSE
CCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVL
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCHH
GLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGP
HHHHCCCCCCCCEEEECCCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
INTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAI
CCCCCCCCCHHHHHCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPY
EHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCC
SGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCCCHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAG
HHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEECCCHHCCCCHHHCCC
QSVSRVGGSAQINAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTASKLERGKRTVEVL
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGG
HHCCCCCCCCCCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LPDAEKFDTAINEFKKSFSKSE
CCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA