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The map label for this gene is acuC

Identifier: 57652033

GI number: 57652033

Start: 1829038

End: 1830207

Strand: Direct

Name: acuC

Synonym: SACOL1785

Alternate gene names: 57652033

Gene position: 1829038-1830207 (Clockwise)

Preceding gene: 57652032

Following gene: 57652044

Centisome position: 65.1

GC content: 34.62

Gene sequence:

>1170_bases
ATGCAACAACATTCATCAAAAACTGCATATGTTTATTCAGATAAGTTATTACAATATCGATTTCATGACCAACATCCCTT
CAATCAAATGCGTTTAAAATTAACAACAGAGCTACTTTTGAATGCAAATTTATTGTCTCCAGAACAAATAGTACAACCTA
GAATTGCAACAGATGACGAATTAATGTTAATTCATAAATATGATTACGTCGAAGCTATTAAGCATGCTTCACATGGCATT
ATCAGTGAAGATGAGGCTAAGAAATATGGATTAAATGATGAAGAGAATGGTCAATTTAAGCATATGCACCGCCATAGTGC
CACAATTGTTGGAGGCGCTTTAACTTTAGCAGATCTTATTATGTCAGGCAAAGTATTAAATGGTTGTCACTTAGGTGGTG
GTTTGCATCACGCTCAACCTGGTCGAGCAAGTGGTTTTTGTATATACAATGATATTGCAATTACCGCACAATACTTAGCT
AAAGAATACAATCAACGCGTTTTAATCATAGATACCGATGCACATCATGGAGATGGTACACAATGGAGTTTCTATGCCGA
TAACCATGTTACTACTTATTCTATCCATGAAACCGGAAAATTTCTTTTCCCAGGCTCTGGTCACTATACTGAGCGCGGTG
AAGATATCGGCTATGGACACACTGTAAATGTCCCACTTGAACCGTATACAGAAGATGCATCATTTTTGGAGTGTTTTAAA
TTAACAGTTGAGCCTGTCGTAAAGAGTTTTAAACCTGATATTATTCTAAGCGTAAATGGTGTCGATATACATTATCGTGA
TCCACTAACTCATCTAAATTGTACGTTACATTCATTATATGAAATTCCATATTTTGTAAAATATTTAGCTGATTCTTATA
CGAATGGAAAGGTAATTATGTTTGGTGGCGGAGGCTACAATATTTGGAGAGTCGTACCACGTGCATGGAGTCATGTATTC
TTAAGTTTAATTGATCAACCAATTCAAAGTGGTTATTTACCGTTAGAATGGATTAATAAATGGAAACATTATTCATCTGA
ATTATTACCTAAAAGATGGGAAGATCGTTTAAATGATTATACCTATGTCCCCCGCACAAAAGAAATTAGTGAAAAAAATA
AAAAATTAGCTTTACATATAGCGAGTTGGTACGAATCTACTCGTCAATAA

Upstream 100 bases:

>100_bases
AATTGGCAAAAACATTACATTAGAACAGCAACAAGCGTTTGATGATATTCGTTATATGAATCGGTTTTTCTTTTAATTTT
TGGAATATCGGAGGGATTAT

Downstream 100 bases:

>100_bases
GTAACCTAATCTGCAACGATTTTAAAAGATAAATAAAAGGCATTCTTCCAACACCCATATAATTTGGGTCGTTAGATGAA
TGCCTAATTTTGTGAATTTA

Product: acetoin utilization protein AcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ

Sequences:

>Translated_389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ
>Mature_389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ

Specific function: Role in growth on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family

Homologues:

Organism=Homo sapiens, GI13128860, Length=328, Percent_Identity=32.0121951219512, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI13128862, Length=388, Percent_Identity=28.3505154639175, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI30795204, Length=340, Percent_Identity=29.7058823529412, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI30795202, Length=340, Percent_Identity=29.7058823529412, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI17158039, Length=340, Percent_Identity=29.7058823529412, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI293336691, Length=323, Percent_Identity=31.2693498452012, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI13128864, Length=377, Percent_Identity=28.1167108753316, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI8923769, Length=310, Percent_Identity=26.4516129032258, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI62750349, Length=337, Percent_Identity=30.2670623145401, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI62750347, Length=337, Percent_Identity=30.2670623145401, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI20070354, Length=272, Percent_Identity=28.6764705882353, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI153085395, Length=213, Percent_Identity=31.924882629108, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI169234807, Length=134, Percent_Identity=40.2985074626866, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI148539870, Length=134, Percent_Identity=40.2985074626866, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI262073092, Length=208, Percent_Identity=28.3653846153846, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI262073088, Length=224, Percent_Identity=27.2321428571429, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226529806, Length=188, Percent_Identity=31.9148936170213, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI217272877, Length=290, Percent_Identity=25.1724137931034, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI209862883, Length=289, Percent_Identity=24.2214532871972, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561978, Length=385, Percent_Identity=30.1298701298701, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17508561, Length=337, Percent_Identity=29.080118694362, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17534739, Length=318, Percent_Identity=30.188679245283, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193209491, Length=241, Percent_Identity=33.6099585062241, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17540334, Length=312, Percent_Identity=29.8076923076923, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=30.0653594771242, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=30.0653594771242, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17537347, Length=316, Percent_Identity=28.1645569620253, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25154020, Length=356, Percent_Identity=24.7191011235955, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25154022, Length=368, Percent_Identity=24.1847826086957, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321244, Length=322, Percent_Identity=32.2981366459627, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6323999, Length=313, Percent_Identity=29.073482428115, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6324307, Length=335, Percent_Identity=28.0597014925373, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6325325, Length=227, Percent_Identity=29.5154185022026, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24657891, Length=321, Percent_Identity=33.6448598130841, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24644244, Length=336, Percent_Identity=30.952380952381, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24642144, Length=339, Percent_Identity=27.4336283185841, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24642142, Length=339, Percent_Identity=27.4336283185841, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24642146, Length=339, Percent_Identity=27.4336283185841, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI281360899, Length=346, Percent_Identity=27.1676300578035, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281360799, Length=356, Percent_Identity=28.9325842696629, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360801, Length=356, Percent_Identity=28.9325842696629, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641720, Length=339, Percent_Identity=29.2035398230088, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24649807, Length=288, Percent_Identity=27.4305555555556, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACUC_STAAC (Q5HF39)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186618.1
- ProteinModelPortal:   Q5HF39
- SMR:   Q5HF39
- STRING:   Q5HF39
- EnsemblBacteria:   EBSTAT00000010210
- GeneID:   3236752
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1785
- TIGR:   SACOL1785
- eggNOG:   COG0123
- GeneTree:   EBGT00050000025543
- HOGENOM:   HBG713516
- OMA:   QHGCDTH
- ProtClustDB:   CLSK885524
- BioCyc:   SAUR93062:SACOL1785-MONOMER
- InterPro:   IPR003085
- InterPro:   IPR000286
- Gene3D:   G3DSA:3.40.800.20
- PANTHER:   PTHR10625
- PRINTS:   PR01272
- PRINTS:   PR01270

Pfam domain/function: PF00850 Hist_deacetyl

EC number: NA

Molecular weight: Translated: 44630; Mature: 44630

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDE
CCCCCCCEEEEEECHHEEEEECCCCCHHHHHHHEEEHHHHCCCCCCHHHHHCCCCCCCCC
LMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLI
EEEEEECHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHCCCEEEHHHHHHHHHH
MSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLAKEYNQRVLIIDTDAHHGDGT
HCCCEECCEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
QWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
EEEEEECCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIM
HHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
FGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDY
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCC
TYVPRTKEISEKNKKLALHIASWYESTRQ
EECCCCHHHHCCCCEEEEEEEHHHHHHCC
>Mature Secondary Structure
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDE
CCCCCCCEEEEEECHHEEEEECCCCCHHHHHHHEEEHHHHCCCCCCHHHHHCCCCCCCCC
LMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLI
EEEEEECHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHCCCEEEHHHHHHHHHH
MSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLAKEYNQRVLIIDTDAHHGDGT
HCCCEECCEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
QWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
EEEEEECCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIM
HHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
FGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDY
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCC
TYVPRTKEISEKNKKLALHIASWYESTRQ
EECCCCHHHHCCCCEEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA