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The map label for this gene is pepQ [C]

Identifier: 57652005

GI number: 57652005

Start: 1796121

End: 1797176

Strand: Direct

Name: pepQ [C]

Synonym: SACOL1756

Alternate gene names: 57652005

Gene position: 1796121-1797176 (Clockwise)

Preceding gene: 57652004

Following gene: 57652008

Centisome position: 63.93

GC content: 33.14

Gene sequence:

>1056_bases
ATGACAAAAATATCAAAAATAATAGACGAATTGAACAATCAACAAGCTGATGCAGCATGGATTACAACACCGTTGAATGT
ATATTATTTTACTGGATACCGTAGCGAACCCCATGAAAGATTATTTGCATTATTGATTAAGAAAGATGGTAAACAAGTAC
TATTTTGTCCAAAAATGGAAGTCGAAGAAGTCAAAGCATCACCTTTCACAGGTGAAATCGTTGGATATTTAGACACTGAA
AACCCTTTTTCACTTTATCCTCAAACAATCAATAAATTACTAATTGAAAGCGAGCACTTAACAGTAGCACGCCAAAAACA
ATTAATCTCTGGTTTCAATGTCAATTCATTCGGAGATGTTGATTTAACAATCAAACAATTGAGAAATATTAAATCCGAAG
ATGAAATTAGCAAAATACGTAAAGCTGCTGAGTTAGCAGATAAGTGTATCGAAATAGGTGTTTCTTATTTAAAAGAAGGT
GTGACTGAATGTGAAGTAGTCAACCATATTGAGCAAACTATCAAACAATATGGCGTCAATGAAATGAGTTTTGATACGAT
GGTTTTATTTGGAGATCATGCCGCATCACCTCATGGCACACCAGGAGATCGCAGATTAAAAAGCAATGAATATGTACTAT
TTGATTTAGGTGTAATTTATGAGCATTATTGTAGCGATATGACACGTACTATTAAATTTGGTGAACCTAGCAAAGAAGCA
CAAGAAATTTATAATATTGTATTAGAAGCAGAAACATCTGCAATCCAAGCAATTAAACCTGGAATACCATTAAAAGATAT
CGATCATATCGCTAGAAATATTATTTCAGAAAAAGGTTATGGTGAATATTTCCCTCATCGCTTAGGTCATGGCCTAGGAT
TACAAGAACATGAATATCAAGATGTTTCAAGTACTAATTCTAATTTGTTAGAAGCTGGCATGGTTATTACAATCGAACCA
GGTATTTATGTACCTGGTGTTGCAGGTGTAAGAATTGAAGATGACATACTTGTCACTAATGAAGGATATGAAGTATTAAC
ACATTACGAAAAATAA

Upstream 100 bases:

>100_bases
TTAAAAATTGAAAATCTAGTTAATGTATTAGCTCGATTTTGAAATCTAATAATAATTGGCATAAAATGGAAGTAATATTA
TGTTGAGGAGTGTTTATAAA

Downstream 100 bases:

>100_bases
GGAGTGGGATAAAAATGAAAAGCTTGTTACAAGCGCATTCTCATTCAGTCAAACACTGCCAATATAACATTGTAGCGCCT
AAGACATAAATTTTTATCCA

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTE
NPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEG
VTECEVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEA
QEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEP
GIYVPGVAGVRIEDDILVTNEGYEVLTHYEK

Sequences:

>Translated_351_residues
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTE
NPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEG
VTECEVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEA
QEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEP
GIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
>Mature_350_residues
TKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTEN
PFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGV
TECEVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQ
EIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPG
IYVPGVAGVRIEDDILVTNEGYEVLTHYEK

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=262, Percent_Identity=29.7709923664122, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI264681563, Length=212, Percent_Identity=30.6603773584906, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI149589008, Length=358, Percent_Identity=24.5810055865922, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI260593665, Length=318, Percent_Identity=24.8427672955975, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260593663, Length=283, Percent_Identity=25.4416961130742, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI93141226, Length=162, Percent_Identity=33.9506172839506, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI264681565, Length=201, Percent_Identity=29.3532338308458, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=23.3870967741935, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788728, Length=362, Percent_Identity=33.4254143646409, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789275, Length=379, Percent_Identity=26.6490765171504, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790282, Length=306, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17508215, Length=422, Percent_Identity=24.4075829383886, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509539, Length=240, Percent_Identity=30.8333333333333, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321118, Length=284, Percent_Identity=29.2253521126761, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320922, Length=295, Percent_Identity=25.4237288135593, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322999, Length=274, Percent_Identity=26.2773722627737, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323273, Length=251, Percent_Identity=28.2868525896414, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920384, Length=262, Percent_Identity=26.7175572519084, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357079, Length=286, Percent_Identity=25.1748251748252, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39554; Mature: 39423

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKME
CCHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCC
VEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDV
HHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCH
DLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTECEVVNHIEQTIKQYGVN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
EMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEA
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHEECCCCCHHH
QEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQ
HHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCC
DVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
CHHCCCCCHHHCCEEEEECCCEECCCCCCEEEECCEEEECCCCHHHCCCCC
>Mature Secondary Structure 
TKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKME
CHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCC
VEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDV
HHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCH
DLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTECEVVNHIEQTIKQYGVN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
EMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEA
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHEECCCCCHHH
QEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQ
HHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCC
DVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
CHHCCCCCHHHCCEEEEECCCEECCCCCCEEEECCEEEECCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]