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The map label for this gene is aroE [H]

Identifier: 57651988

GI number: 57651988

Start: 1681391

End: 1682197

Strand: Reverse

Name: aroE [H]

Synonym: SACOL1652

Alternate gene names: 57651988

Gene position: 1682197-1681391 (Counterclockwise)

Preceding gene: 57651989

Following gene: 57651987

Centisome position: 59.88

GC content: 31.35

Gene sequence:

>807_bases
ATGAAATTTGCAGTTATAGGAAATCCTATTTCACATTCCTTGTCGCCCGTTATGCATAGAGCAAATTTTAATTCTTTAGG
ATTAGATGATACTTATGAAGCTTTAAATATTCCAATTGAAGATTTTCATTTAATTAAAGAAATTATTTCGAAAAAAGAAT
TAGAAGGCTTTAATATCACAATTCCTCATAAAGAACGTATCATACCGTATTTAGATTATGTTGATGAACAAGCGATTAAT
GCAGGTGCAGTTAACACTGTTTTGATAAAAGATGGCAAGTGGATAGGGTATAATACAGATGGTATTGGTTATGTTAAAGG
ATTGCACAGCGTTTATCCAGATTTAGAAAATGCATACATTTTAATTTTGGGCGCAGGTGGTGCAAGTAAAGGTATTGCTT
ATGAATTAGCAAAATTTGTAAAGCCCAAATTAACTGTTGCGAATAGAACGATGGCTCGTTTTGAATCTTGGAATTTAAAT
ATAAACCAAATTTCATTAGCAGATGCTGAAAAGTATTTAGCTGAATTCGATATCGTTATTAATACAACACCAGCGGGTAT
GGCTGGAAATAACGAAAGTATTATTAATTTAAAGCATCTTTCTCCCAATACTTTAATGAGTGATATTGTTTATATACCGT
ATAAAACACCTATTTTAGAGGAAGCAGAGCGCAAGGGAAACCATATTTATAATGGCTTAGATATGTTTGTTTACCAGGGT
GCGGAAAGCTTTAAAATTTGGACTAATAAAGATGCTGATATTAATTCTATGAAAACAGCAGTTTTACAACAATTAAAAGG
AGAATAA

Upstream 100 bases:

>100_bases
GGCTTTATAACTATAGGACCAGGGGCTAAAGTAATCGTTCGTGTTCCTAAAAATGTTGATGTTGTATTAAGAAATTCTAT
TTTATAAGGTGATTAAAAAA

Downstream 100 bases:

>100_bases
CATATGCTTACTGGCAAACAAAAAAGATACTTAAGAAGTTTAGCACACAATATTGATCCGATTTTTCAAATTGGAAAAGG
CGGTATCAACGAAAATATGA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELEGFNITIPHKERIIPYLDYVDEQAIN
AGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLN
INQISLADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
AESFKIWTNKDADINSMKTAVLQQLKGE

Sequences:

>Translated_268_residues
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELEGFNITIPHKERIIPYLDYVDEQAIN
AGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLN
INQISLADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
AESFKIWTNKDADINSMKTAVLQQLKGE
>Mature_268_residues
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELEGFNITIPHKERIIPYLDYVDEQAIN
AGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLN
INQISLADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
AESFKIWTNKDADINSMKTAVLQQLKGE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=279, Percent_Identity=31.8996415770609, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789675, Length=274, Percent_Identity=33.2116788321168, Blast_Score=135, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=280, Percent_Identity=28.2142857142857, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29880; Mature: 29880

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELEGFNIT
CEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEE
IPHKERIIPYLDYVDEQAINAGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYI
CCCHHCCCHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHCCCCCCCEE
LILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLNINQISLADAEKYLAEFDIVI
EEEECCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHEEEEEE
NTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
ECCCCCCCCCCCCEEEEECCCCCHHHHCEEEECCCCCHHHHHHHCCCEECCCCEEEEECC
AESFKIWTNKDADINSMKTAVLQQLKGE
CCCEEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELEGFNIT
CEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEE
IPHKERIIPYLDYVDEQAINAGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYI
CCCHHCCCHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHCCCCCCCEE
LILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLNINQISLADAEKYLAEFDIVI
EEEECCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHEEEEEE
NTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
ECCCCCCCCCCCCEEEEECCCCCHHHHCEEEECCCCCHHHHHHHCCCEECCCCEEEEECC
AESFKIWTNKDADINSMKTAVLQQLKGE
CCCEEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA