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The map label for this gene is glk [H]

Identifier: 57651940

GI number: 57651940

Start: 1635252

End: 1636238

Strand: Reverse

Name: glk [H]

Synonym: SACOL1604

Alternate gene names: 57651940

Gene position: 1636238-1635252 (Counterclockwise)

Preceding gene: 57651941

Following gene: 57651939

Centisome position: 58.24

GC content: 34.65

Gene sequence:

>987_bases
ATGACAAAAATTATTTTAGCAGCTGATGTAGGCGGGACGACTTGTAAATTAGGTATTTTCACACCTGAATTAGAACAATT
ACATAAATGGTCTATTCACACTGATACATCTGATAGTACAGGATATACACTTTTGAAAGGAATTTATGATTCGTTTGTTG
AAAAAGTAAATGAAAATAATTATAATTTTTCAAATGTACTTGGCGTAGGTATTGGTGTACCAGGTCCTGTTGACTTTGAA
AAAGGTACAGTAAATGGAGCAGTAAACTTATATTGGCCAGAAAAAGTTAATGTACGTGAGATTTTTGAACAATTCGTTGA
TTGTCCAGTGTATGTAGATAATGATGCTAACATAGCTGCTTTAGGGGAGAAACACAAAGGTGCTGGTGAAGGTGCCGATG
ATGTTGTTGCCATCACACTTGGTACAGGTCTAGGTGGAGGAATTATTTCAAATGGTGAAATCGTACATGGTCATAATGGC
TCTGGCGCAGAAATAGGTCATTTTAGAGCAGACTTCGATCAACGATTTAAATGTAATTGTGGTCGTTCTGGATGTATTGA
AACAGTTGCTTCAGCGACAGGCGTTGTTAACTTAGTTAACTTCTACTATCCGAAGTTGACGTTTAGATCTTCTATATTAG
AATTGATTAAAGAAAATAAGGTTACAGCAAAAGCTGTTTTTGATGCGGCAAAAGCTGGTGACCAATTCTGTATTTTCATT
ACTGAAAAGGTTGCAAACTATATTGGATATTTATGTAGTATTATTAGTGTTACAAGTAATCCGAAATATATCGTTCTAGG
TGGAGGAATGTCTACTGCAGGACCTATTTTAATTGAAAATATTAAAACAGAATATCATAATTTAACATTTGCACCTGCTC
AATTTGAAACTGAAATTGTACAAGCGAAATTAGGTAATGATGCAGGTATTACAGGAGCAGCAGGATTAATCAAGACCTAT
GTATTAGATAAAGAGGGGGTAAAATAA

Upstream 100 bases:

>100_bases
TTCAACAGGAGATTTCATCATTGTATCAATATGAACTGTTATCTAAGGAAGAATATTTGAAATGTACGTTGATAATTAAT
CAGAGAAGGAATGAACAGAA

Downstream 100 bases:

>100_bases
TGGCTATTGTTGATGTGGTTGTTATTCCAGTTGGAACGGAAGGTCCGAGTGTTAGTAAATATATTGCAGATATTCAGAAA
AAACTTCAAGAATATAAAGC

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTKIILAADVGGTTCKLGIFTPELEQLHKWSIHTDTSDSTGYTLLKGIYDSFVEKVNENNYNFSNVLGVGIGVPGPVDFE
KGTVNGAVNLYWPEKVNVREIFEQFVDCPVYVDNDANIAALGEKHKGAGEGADDVVAITLGTGLGGGIISNGEIVHGHNG
SGAEIGHFRADFDQRFKCNCGRSGCIETVASATGVVNLVNFYYPKLTFRSSILELIKENKVTAKAVFDAAKAGDQFCIFI
TEKVANYIGYLCSIISVTSNPKYIVLGGGMSTAGPILIENIKTEYHNLTFAPAQFETEIVQAKLGNDAGITGAAGLIKTY
VLDKEGVK

Sequences:

>Translated_328_residues
MTKIILAADVGGTTCKLGIFTPELEQLHKWSIHTDTSDSTGYTLLKGIYDSFVEKVNENNYNFSNVLGVGIGVPGPVDFE
KGTVNGAVNLYWPEKVNVREIFEQFVDCPVYVDNDANIAALGEKHKGAGEGADDVVAITLGTGLGGGIISNGEIVHGHNG
SGAEIGHFRADFDQRFKCNCGRSGCIETVASATGVVNLVNFYYPKLTFRSSILELIKENKVTAKAVFDAAKAGDQFCIFI
TEKVANYIGYLCSIISVTSNPKYIVLGGGMSTAGPILIENIKTEYHNLTFAPAQFETEIVQAKLGNDAGITGAAGLIKTY
VLDKEGVK
>Mature_327_residues
TKIILAADVGGTTCKLGIFTPELEQLHKWSIHTDTSDSTGYTLLKGIYDSFVEKVNENNYNFSNVLGVGIGVPGPVDFEK
GTVNGAVNLYWPEKVNVREIFEQFVDCPVYVDNDANIAALGEKHKGAGEGADDVVAITLGTGLGGGIISNGEIVHGHNGS
GAEIGHFRADFDQRFKCNCGRSGCIETVASATGVVNLVNFYYPKLTFRSSILELIKENKVTAKAVFDAAKAGDQFCIFIT
EKVANYIGYLCSIISVTSNPKYIVLGGGMSTAGPILIENIKTEYHNLTFAPAQFETEIVQAKLGNDAGITGAAGLIKTYV
LDKEGVK

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=270, Percent_Identity=30.3703703703704, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI298566325, Length=270, Percent_Identity=30.3703703703704, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4885285, Length=270, Percent_Identity=30.3703703703704, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI190014632, Length=270, Percent_Identity=30.3703703703704, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1787878, Length=276, Percent_Identity=25.7246376811594, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786891, Length=296, Percent_Identity=25.6756756756757, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787363, Length=318, Percent_Identity=29.2452830188679, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081733, Length=326, Percent_Identity=27.6073619631902, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082127, Length=185, Percent_Identity=25.9459459459459, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 35078; Mature: 34947

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIILAADVGGTTCKLGIFTPELEQLHKWSIHTDTSDSTGYTLLKGIYDSFVEKVNENN
CCEEEEEECCCCCEEEEEECCCCHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCC
YNFSNVLGVGIGVPGPVDFEKGTVNGAVNLYWPEKVNVREIFEQFVDCPVYVDNDANIAA
CCHHHEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEECCCCCEEE
LGEKHKGAGEGADDVVAITLGTGLGGGIISNGEIVHGHNGSGAEIGHFRADFDQRFKCNC
ECCCCCCCCCCCCCEEEEEECCCCCCCEECCCEEEECCCCCCCCCCCCCCCCCCCEECCC
GRSGCIETVASATGVVNLVNFYYPKLTFRSSILELIKENKVTAKAVFDAAKAGDQFCIFI
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEE
TEKVANYIGYLCSIISVTSNPKYIVLGGGMSTAGPILIENIKTEYHNLTFAPAQFETEIV
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEHHHHHHCCEEECCCHHHHHHH
QAKLGNDAGITGAAGLIKTYVLDKEGVK
HHHCCCCCCCCHHHHHHHHHEECCCCCC
>Mature Secondary Structure 
TKIILAADVGGTTCKLGIFTPELEQLHKWSIHTDTSDSTGYTLLKGIYDSFVEKVNENN
CEEEEEECCCCCEEEEEECCCCHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCC
YNFSNVLGVGIGVPGPVDFEKGTVNGAVNLYWPEKVNVREIFEQFVDCPVYVDNDANIAA
CCHHHEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEECCCCCEEE
LGEKHKGAGEGADDVVAITLGTGLGGGIISNGEIVHGHNGSGAEIGHFRADFDQRFKCNC
ECCCCCCCCCCCCCEEEEEECCCCCCCEECCCEEEECCCCCCCCCCCCCCCCCCCEECCC
GRSGCIETVASATGVVNLVNFYYPKLTFRSSILELIKENKVTAKAVFDAAKAGDQFCIFI
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEE
TEKVANYIGYLCSIISVTSNPKYIVLGGGMSTAGPILIENIKTEYHNLTFAPAQFETEIV
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEHHHHHHCCEEECCCHHHHHHH
QAKLGNDAGITGAAGLIKTYVLDKEGVK
HHHCCCCCCCCHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592379 [H]