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The map label for this gene is frr

Identifier: 57651829

GI number: 57651829

Start: 1287303

End: 1287857

Strand: Direct

Name: frr

Synonym: SACOL1278

Alternate gene names: 57651829

Gene position: 1287303-1287857 (Clockwise)

Preceding gene: 57651828

Following gene: 57651830

Centisome position: 45.82

GC content: 34.59

Gene sequence:

>555_bases
ATGAGTGACATTATTAATGAAACTAAATCAAGAATGCAAAAATCAATCGAAAGCTTATCACGTGAATTAGCTAACATCAG
TGCAGGAAGAGCTAATTCAAATTTATTAAACGGCGTAACAGTTGATTACTATGGTGCACCAACACCTGTACAACAATTAG
CAAGCATCAATGTTCCAGAAGCACGTTTACTTGTTATTTCTCCATACGACAAAACTTCTGTAGCTGACATCGAAAAAGCG
ATAATAGCAGCTAACTTAGGTGTTAACCCAACAAGTGATGGTGAAGTGATACGTATTGCTGTACCTGCCTTAACAGAAGA
ACGTAGAAAAGAGCGCGTTAAAGATGTTAAGAAAATTGGTGAAGAAGCTAAAGTATCTGTTCGAAATATTCGTCGTGATA
TGAATGATCAGTTGAAAAAAGATGAAAAAAATGGCGACATTACTGAAGATGAGTTGAGAAGTGGTACTGAAGATGTTCAG
AAAGCAACAGACAATTCAATAAAAGAAATTGATCAAATGATTGCTGATAAAGAAAAAGATATTATGTCAGTATAA

Upstream 100 bases:

>100_bases
AACTGTTTTCTCTATTATGGAAGAAGGAAATATTAAACGTGCTGTTATGGGTGAAAAGATAGGTACGTTAATTACAAAAT
AAATTTAGAGGTGTAAAATA

Downstream 100 bases:

>100_bases
AACTAATATACAATGACATATTAAAATGCCAGTATTAAACGATAATGTAACATTTAAAATGGGCATGTTTAATTAAATCA
AAGATGCATGTGATAATTTA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPEARLLVISPYDKTSVADIEKA
IIAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQ
KATDNSIKEIDQMIADKEKDIMSV

Sequences:

>Translated_184_residues
MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPEARLLVISPYDKTSVADIEKA
IIAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQ
KATDNSIKEIDQMIADKEKDIMSV
>Mature_183_residues
SDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPEARLLVISPYDKTSVADIEKAI
IAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQK
ATDNSIKEIDQMIADKEKDIMSV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=185, Percent_Identity=28.6486486486486, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=45.6521739130435, Blast_Score=170, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=23.4285714285714, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_STAA1 (A7X1N7)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441839.1
- ProteinModelPortal:   A7X1N7
- SMR:   A7X1N7
- STRING:   A7X1N7
- EnsemblBacteria:   EBSTAT00000003509
- GeneID:   5561294
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1249
- eggNOG:   COG0233
- GeneTree:   EBGT00050000025258
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   SAUR418127:SAHV_1249-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20353; Mature: 20222

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCEEECCCCCHHHHHHHHCCCCC
ARLLVISPYDKTSVADIEKAIIAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIG
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
EEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQKATDNSIKEIDQMIADKEKD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHCCHHH
IMSV
HHCC
>Mature Secondary Structure 
SDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCEEECCCCCHHHHHHHHCCCCC
ARLLVISPYDKTSVADIEKAIIAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIG
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
EEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQKATDNSIKEIDQMIADKEKD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHCCHHH
IMSV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA