Click here to switch to the map view.

The map label for this gene is rnhB [H]

Identifier: 57651813

GI number: 57651813

Start: 1269776

End: 1270543

Strand: Direct

Name: rnhB [H]

Synonym: SACOL1261

Alternate gene names: 57651813

Gene position: 1269776-1270543 (Clockwise)

Preceding gene: 57651812

Following gene: 57651814

Centisome position: 45.2

GC content: 35.16

Gene sequence:

>768_bases
ATGACGCTAACAATTAAAGAAGTTACGCAGTTGATTAATGCGGTTAATACAATAGAAGAATTAGAAAATCATGAATGCTT
TTTAGATGAGCGAAAAGGTGTTCAAAATGCCATAGCTAGGCGCAGAAAAGCGTTAGAAAAAGAACAAGCTTTAAAAGAAA
AGTATGTTGAAATGACTTACTTTGAAAATGAAATATTAAAAGAGCATCCTAATGCTATTATTTGTGGGATTGATGAAGTT
GGAAGAGGACCTTTAGCAGGTCCAGTCGTTGCATGCGCAACAATTTTAAATTCAAATCACAATTATTTGGGCCTTGATGA
CTCGAAAAAAGTACCTGTTACGAAACGTCTAGAATTAAATGAAGCACTAAAAAATGAAGTTACTGCTTTTGCATATGGGA
TCGCGACAGCTGAAGAAATAGATGAATTTAATATTTATAAAGCTACTCAAATCGCCATGCAGCGAGCTATTGATGGATTA
TCAGTACAACCAACGCATTTATTGATAGACGCGATGACGCTTGATAATGCACTGCCTCAAGTATCTTTAATCAAGGGTGA
TGCAAGAAGTGTGTCCATTGCAGCTGCAAGTATCATGGCAAAGGTTTTTCGTGATGATTATATGACACAGTTATCTAAAG
ATTATCCTGAATATGGTTTTGAAAAAAACGCGGGTTACGGTACCAAACAACATTTACTAGCAATCGATGATATTGGCATT
ATGAAAGAGCATAGAAAAAGCTTTGAACCTATAAAATCGTTACTGTAA

Upstream 100 bases:

>100_bases
TACGAAGCAGTCATTGAACTGATTATTTATGATATTCGAAATGCTAAAATAGGAAATTATTGTTTTGATATTTTTAAAGA
TATGACTGAGGAATTAGCAA

Downstream 100 bases:

>100_bases
ATCGTAAAATTCAATTAAATGATAAAAAAGTAGCATTTAAGTTTACAATAGCGCTTACATTTTTTATAATTGTAAGGGAA
CTTAACCTAAGTAACAGGAG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEV
GRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGL
SVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGI
MKEHRKSFEPIKSLL

Sequences:

>Translated_255_residues
MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEV
GRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGL
SVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGI
MKEHRKSFEPIKSLL
>Mature_254_residues
TLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVG
RGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLS
VQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIM
KEHRKSFEPIKSLL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=184, Percent_Identity=44.0217391304348, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 28513; Mature: 28382

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTY
CEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELN
HHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHH
EALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQ
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
VSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGI
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEHHHHH
MKEHRKSFEPIKSLL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTY
EEEHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELN
HHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHH
EALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQ
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
VSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGI
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEHHHHH
MKEHRKSFEPIKSLL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA