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The map label for this gene is fabD

Identifier: 57651798

GI number: 57651798

Start: 1253415

End: 1254341

Strand: Direct

Name: fabD

Synonym: SACOL1244

Alternate gene names: 57651798

Gene position: 1253415-1254341 (Clockwise)

Preceding gene: 57651797

Following gene: 57651799

Centisome position: 44.61

GC content: 33.76

Gene sequence:

>927_bases
ATGAGTAAAACAGCAATTATTTTTCCGGGACAAGGTGCCCAAAAAGTTGGTATGGCGCAAGATTTGTTTAACAACAATGA
TCAAGCAACTGAAATTTTAACTTCAGCAGCGAACACATTAGACTTTGATATTTTAGAGACAATGTTTACTGATGAAGAAG
GTAAATTGGGTGAAACTGAAAACACACAACCAGCTTTATTGACGCATAGTTCGGCATTATTAGCAGCGCTAAAAAATTTG
AATCCTGATTTTACTATGGGGCATAGTTTAGGTGAATATTCAAGTTTAGTTGCAGCTGACGTATTATCATTTGAAGATGC
AGTTAAAATTGTTAGAAAACGTGGTCAATTAATGGCGCAAGCATTTCCTACTGGTGTAGGAAGCATGGCTGCAGTATTGG
GATTAGATTTTGATAAAGTCGATGAAATTTGTAAGTCATTATCATCTGATGACAAAATAATTGAACCAGCAAACATTAAT
TGCCCAGGTCAAATTGTTGTTTCAGGTCACAAAGCTTTAATTGATGAGCTAGTAGAAAAAGGTAAATCATTAGGTGCAAA
ACGTGTCATGCCTTTAGCAGTATCTGGACCATTCCATTCATCGCTAATGAAAGTGATTGAAGAAGATTTTTCAAGTTACA
TTAATCAATTTGAATGGCGTGATGCTAAGTTTCCTGTAGTTCAAAATGTAAATGCGCAAGGTGAAACTGACAAAGAAGTA
ATTAAATCTAATATGGTCAAGCAATTATATTCACCAGTACAATTCATTAACTCAACAGAATGGCTAATAGACCAAGGTGT
TGATCATTTTATTGAAATTGGTCCTGGAAAAGTTTTATCTGGCTTAATTAAAAAAATAAATAGAGATGTTAAGTTAACAT
CAATTCAAACTTTAGAAGATGTGAAAGGATGGAATGAAAATGACTAA

Upstream 100 bases:

>100_bases
AGTTCAAATGCTAAAGCTTTTTATTCTGCAATTAGACAAGCGAAAATCGCAGGAGAACAAAATATTGTACAAACAATGAA
AGAGACTGTAGGTGAATCAA

Downstream 100 bases:

>100_bases
GAGTGCTTTAGTAACAGGTGCATCAAGAGGAATTGGACGTAGTATTGCGTTACAATTAGCAGAAGAAGGATATAATGTAG
CAGTAAACTATGCAGGCAGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAANTLDFDILETMFTDEEGKLGETENTQPALLTHSSALLAALKNL
NPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANIN
CPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEV
IKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND

Sequences:

>Translated_308_residues
MSKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAANTLDFDILETMFTDEEGKLGETENTQPALLTHSSALLAALKNL
NPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANIN
CPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEV
IKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND
>Mature_307_residues
SKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAANTLDFDILETMFTDEEGKLGETENTQPALLTHSSALLAALKNLN
PDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINC
PGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEVI
KSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family

Homologues:

Organism=Homo sapiens, GI51243059, Length=323, Percent_Identity=28.4829721362229, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1787334, Length=289, Percent_Identity=40.1384083044983, Blast_Score=221, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=29.2096219931272, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=311, Percent_Identity=25.4019292604502, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=31.5614617940199, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FABD_STAAC (Q5HGK3)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186104.1
- ProteinModelPortal:   Q5HGK3
- SMR:   Q5HGK3
- STRING:   Q5HGK3
- EnsemblBacteria:   EBSTAT00000008683
- GeneID:   3238625
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1244
- TIGR:   SACOL1244
- eggNOG:   COG0331
- GeneTree:   EBGT00050000023910
- HOGENOM:   HBG687898
- OMA:   FKDAVPL
- ProtClustDB:   CLSK885219
- BioCyc:   SAUR93062:SACOL1244-MONOMER
- GO:   GO:0005488
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036
- Gene3D:   G3DSA:3.40.366.10
- TIGRFAMs:   TIGR00128

Pfam domain/function: PF00698 Acyl_transf_1; SSF52151 Acyl_Trfase/lysoPlipase; SSF55048 Malonyl_transacylase_ACP-bd

EC number: =2.3.1.39

Molecular weight: Translated: 33636; Mature: 33504

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00157 RUBISCO_LARGE

Important sites: ACT_SITE 89-89 ACT_SITE 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAANTLDFDILETMFTDEEGKLGETE
CCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQ
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEK
HHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCHHHHHHHHHHH
GKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEV
HHHCCCHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHH
IKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLED
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHHHH
VKGWNEND
HCCCCCCC
>Mature Secondary Structure 
SKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAANTLDFDILETMFTDEEGKLGETE
CCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQ
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEK
HHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCHHHHHHHHHHH
GKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEV
HHHCCCHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHH
IKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLED
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHHHH
VKGWNEND
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA