Click here to switch to the map view.

The map label for this gene is mntH [H]

Identifier: 57651714

GI number: 57651714

Start: 1123744

End: 1125096

Strand: Reverse

Name: mntH [H]

Synonym: SACOL1114

Alternate gene names: 57651714

Gene position: 1125096-1123744 (Counterclockwise)

Preceding gene: 57651715

Following gene: 57651700

Centisome position: 40.05

GC content: 32.0

Gene sequence:

>1353_bases
ATGAATAATAAACGACATTCAACAAATGAACAATTAAGTTTAGACGAAATAAACAATACAATTAAATTCGATCATCGCAG
TTCAAATAAACAGAAATTTTTATCATTTCTTGGACCTGGGTTATTAGTCGCTGTTGGTTACATGGATCCCGGAAACTGGA
TAACATCAATGCAAGGTGGCGCCCAATATGGCTATACTTTGCTATTCGTAATTCTTATTTCAAGTTTATCAGCAATGTTA
CTTCAAAGCATGACAGTGAGATTAGGAATAGCAACAGGTATGGACTTAGCTCAAATGACACGACATTATTTATCAAGACC
TATTGCTATAATCTTTTGGATCATTGCAGAACTAGCAATTATCGCTACAGATATTGCTGAGGTTATTGGTAGTGCTATTG
CTCTTAATCTCCTATTTAACATACCTTTAATCGTCGGTGCACTAATAACTGTACTTGATGTATTTTTACTACTTTTTATA
ATGAAATATGGTTTTAGAAAAATTGAAGCTATTGTTGGTACATTAATTTTCACAGTGTTATTCATCTTTATATTTGAAGT
CTATATTTCATCACCACAGTTGAATGCTGTGTTAAATGGATTTATACCACATAGTGAAATCATTACAAATAACGGCATTC
TCTATATTGCATTAGGTATTATTGGCGCTACAATTATGCCTCATAATTTGTACTTACATTCATCAATTGTACAATCTAGA
ACATACTCAAGACATAACAATGAAGAAAAAGCGCAAGCGATTAAATTTGCTACGATAGATTCGAACATTCAGTTATCAAT
CGCATTTGTAGTCAATTGCTTATTATTAGTGTTAGGAGCATCACTATTTTTCAACTCAAATGCTGACGATTTAGGTGGTT
TCTATGATTTATATCACGCCTTAAAAACTGAACCTGTACTAGGTGCAACAATGGGTGCAATCATGAGTACATTATTTGCA
GTTGCATTATTAGCGTCAGGTCAAAATTCAACGATTACTGGTACTTTAGCAGGACAAATTGTAATGGAAGGATTTTTAAG
ATTACACATACCAAATTGGTTAAGACGTTTAATTACACGTTCTCTTGCTGTCATTCCTGTTATCGTATGCTTAATCATTT
TTAAAGGTAATGCAGCTAAAATTGAGCAACTACTTGTATTCTCTCAAGTATTTTTAAGTATTGCTCTGCCATTCTGTTTA
ATACCATTACAATTGGCTACTAGTAATAAAGACTTGATGGGACCTTTCTATAATAAAACATGGGTTAATATCATTTCATG
GACACTTATTATTATTCTAAGTATTTTAAATGTCTATTTAATCGTTCAAACATTCCAAGAACTACAAAGTTAA

Upstream 100 bases:

>100_bases
ATAATAATTCATACTTTTAAAAAAATTAAAATAAATTTAGGTTGACCTGAACATTTTATTAGGTTATTATATTGTCCATA
AGAAGTAGAGGTGAGTCAAA

Downstream 100 bases:

>100_bases
AAATAAAACCATTAAAATGTTGGTTGTATCTAATAATTAACAACTTAACATTTTAATGGTTTTTCTTTTGCTATGAACAT
ATTAATGATAAATATACTCA

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAML
LQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFI
MKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFA
VALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCL
IPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS

Sequences:

>Translated_450_residues
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAML
LQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFI
MKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFA
VALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCL
IPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
>Mature_450_residues
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAML
LQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFI
MKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFA
VALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCL
IPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=439, Percent_Identity=35.7630979498861, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI295293167, Length=463, Percent_Identity=37.5809935205184, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI295293175, Length=463, Percent_Identity=37.5809935205184, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI295293173, Length=463, Percent_Identity=37.5809935205184, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI10835169, Length=463, Percent_Identity=37.5809935205184, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI295293178, Length=463, Percent_Identity=37.1490280777538, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI295293171, Length=463, Percent_Identity=37.5809935205184, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI295293169, Length=463, Percent_Identity=37.5809935205184, Blast_Score=250, Evalue=2e-66,
Organism=Escherichia coli, GI1788736, Length=423, Percent_Identity=35.4609929078014, Blast_Score=261, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI17569473, Length=416, Percent_Identity=39.1826923076923, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI193210616, Length=461, Percent_Identity=36.0086767895879, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI71999499, Length=469, Percent_Identity=34.3283582089552, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71993856, Length=249, Percent_Identity=36.5461847389558, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324450, Length=425, Percent_Identity=38.3529411764706, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6323062, Length=404, Percent_Identity=42.3267326732673, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6321841, Length=420, Percent_Identity=36.9047619047619, Blast_Score=242, Evalue=8e-65,
Organism=Drosophila melanogaster, GI24648607, Length=471, Percent_Identity=36.5180467091295, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI281362176, Length=471, Percent_Identity=36.5180467091295, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24648609, Length=471, Percent_Identity=36.5180467091295, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI45553443, Length=440, Percent_Identity=37.5, Blast_Score=272, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 49725; Mature: 49725

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGG
CCCCCCCCCCCCCHHHHCCCEEECCCCCCHHHHHHHHCCCHHEEEECCCCCCHHHCCCCC
AQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHH
IATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTLIFTVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
HHHHHHHHHCCCHHHHHHHCCCCCHHHEECCCCCEEEHHHHHHHHCCCHHHHHHHHHHHH
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHA
HHHHCCCHHHHHHHEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITR
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
WVNIISWTLIIILSILNVYLIVQTFQELQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGG
CCCCCCCCCCCCCHHHHCCCEEECCCCCCHHHHHHHHCCCHHEEEECCCCCCHHHCCCCC
AQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHH
IATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTLIFTVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
HHHHHHHHHCCCHHHHHHHCCCCCHHHEECCCCCEEEHHHHHHHHCCCHHHHHHHHHHHH
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHA
HHHHCCCHHHHHHHEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITR
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
WVNIISWTLIIILSILNVYLIVQTFQELQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA