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The map label for this gene is queC

Identifier: 57651551

GI number: 57651551

Start: 792803

End: 793471

Strand: Reverse

Name: queC

Synonym: SACOL0772

Alternate gene names: 57651551

Gene position: 793471-792803 (Counterclockwise)

Preceding gene: 57651563

Following gene: 57651550

Centisome position: 28.24

GC content: 34.53

Gene sequence:

>669_bases
ATGGAAAGTGTATTAAATAATGAAAAAGCCATCGTTGTCTTTAGTGGTGGTCAAGACAGTACAACATGTCTCTTTTATGC
AAAAAAACATTTCAAAGAAGTTGAACTCGTAACGTTTAATTATGGCCAAAGACATGATACTGAAATTGAAGTCGCAAAAC
AAATTGCACAAGATCAAGGAATGAAACATCACGTTTTAGATATGTCATTATTATCACAACTTACTCCAAACGCATTAACA
CAACATGATATGGAAATTACTAATAATGAAGATGGTATACCTAATACATTTGTTCCAGCTAGAAATTTACTTTTCTTGTC
GTTTGCAGGCGCTCTAGCTTATCAAATTGGGGCTAAGCATATTATTACAGGCGTATGTGAAACAGACTTTTCAGGCTACC
CAGACTGTCGCGATAGTTTTATAAAATCAATGAACGTAACATTAAGCCTAGCTATGGACAAAGATTTTGTCATTCATACT
CCTTTAATGTGGTTAAACAAAGCAGAAACGTGGAAATTAAGTGATGAACTCGAAGTTTTAGATTATATTCGTACAAAAAC
ATTAACATGCTATAACGGTATCATTGGGGATGGCTGTGGTGAATGTCCAGCTTGTCATTTACGTCAACGTGGACTAAATC
AATATCTTGAAAGTAAAGGAGCGCTTTAA

Upstream 100 bases:

>100_bases
TTTATGGAGATAGGCTTTTTTTATTTTATAAATTAAAAACGGGCTTATCAATGCCATTAACCTCTTTATTAATATTATTA
ATGATAGGAGCAATTACAAA

Downstream 100 bases:

>100_bases
AATGTTACAACAAATCTATCCTAGTACAACGCATCCATATCAATTCGAATTAAATAAAGATTTTAATTTTTCGGCTGCAC
ATCACATTCCATGTGAAGAA

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALT
QHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHT
PLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL

Sequences:

>Translated_222_residues
MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALT
QHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHT
PLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
>Mature_222_residues
MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALT
QHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHT
PLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=216, Percent_Identity=56.9444444444444, Blast_Score=264, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_STAA1 (A7WZJ4)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441299.1
- ProteinModelPortal:   A7WZJ4
- SMR:   A7WZJ4
- STRING:   A7WZJ4
- EnsemblBacteria:   EBSTAT00000004980
- GeneID:   5559873
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0709
- eggNOG:   COG0603
- GeneTree:   EBGT00050000023659
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   CLSK884844
- BioCyc:   SAUR418127:SAHV_0709-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24888; Mature: 24888

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQG
CCCCCCCCCEEEEEECCCCCCEEEEEEHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHCC
MKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKH
CHHHHHHHHHHHHCCCCHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHH
IITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVL
HHHHHHCCCCCCCCHHHHHHHHHCCEEEEEEECCCEEEECCHHHHCCCCCEECCHHHHHH
DYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQG
CCCCCCCCCEEEEEECCCCCCEEEEEEHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHCC
MKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKH
CHHHHHHHHHHHHCCCCHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHH
IITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVL
HHHHHHCCCCCCCCHHHHHHHHHCCEEEEEEECCCEEEECCHHHHCCCCCEECCHHHHHH
DYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA